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FRISC: The Faculty Research Interests Science Comparator |
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Associate Professor of Cell Biology
Cell Regulation
Genetics and
Development
Office: (214) 648-9226
FAX: (214) 648-8694
Building K, Room 2.216
Email: john.abrams@utsouthwestern.edu
Dredd, a novel effector of the apoptosis activators reaper, grim, and hid in Drosophila.
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Score: 0.829 | |
Dark is a Drosophila homologue of Apaf-1/CED-4 and functions in an evolutionarily conserved death pathway.
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Score: 0.688 | |
Mechanisms of steroid-triggered programmed cell death in Drosophila.
|
Score: 0.638 | |
An emerging blueprint for apoptosis in Drosophila.
|
Score: 0.564 | |
grim, a novel cell death gene in Drosophila.
|
Score: 0.564 | |
Down-regulation of DIAP1 triggers a novel Drosophila cell death pathway mediated by Dark and DRONC.
|
Score: 0.545 | |
HAC-1, a Drosophila homolog of APAF-1 and CED-4 functions in developmental and radiation-induced apoptosis.
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Score: 0.537 | |
DCP-1, a Drosophila cell death protease essential for development.
|
Score: 0.527 | |
An essential role for the caspase dronc in developmentally programmed cell death in Drosophila.
|
Score: 0.520 | |
Unrestrained caspase-dependent cell death caused by loss of Diap1 function requires the Drosophila Apaf-1 homolog, Dark.
|
Score: 0.516 | |
The fly caspases.
|
Score: 0.509 | |
The proapoptotic function of Drosophila Hid is conserved in mammalian cells.
|
Score: 0.498 | |
Facing death in the fly: genetic analysis of apoptosis in Drosophila.
|
Score: 0.496 | |
Genetic regulation of programmed cell death in Drosophila.
|
Score: 0.495 | |
Autophagic programmed cell death in Drosophila.
|
Score: 0.493 | |
Mitochondria and apoptosis.
|
Score: 0.492 | |
Programmed cell death in Drosophila.
|
Score: 0.491 | |
Cell death regulation by the mammalian IAP antagonist Diablo/Smac.
|
Score: 0.487 | |
Drosophila grim induces apoptosis in mammalian cells.
|
Score: 0.482 | |
Programmed cell death in invertebrates.
|
Score: 0.478 | |
Cell death: drosophila Apaf-1 - no longer in the (d)Ark.
|
Score: 0.477 | |
Dissecting the regulation of the Drosophila cell death activator reaper.
|
Score: 0.475 | |
Caspases in developmental cell death.
|
Score: 0.470 | |
Altered cytochrome c display precedes apoptotic cell death in Drosophila.
|
Score: 0.466 | |
The Drosophila caspase DRONC cleaves following glutamate or aspartate and is regulated by DIAP1, HID, and GRIM.
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Score: 0.464 | |
A steroid-triggered transcriptional hierarchy controls salivary gland cell death during Drosophila metamorphosis.
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Score: 0.463 | |
The damage-responsive Drosophila gene sickle encodes a novel IAP binding protein similar to but distinct from reaper, grim, and hid.
|
Score: 0.460 | |
The head involution defective gene of Drosophila melanogaster functions in programmed cell death.
|
Score: 0.457 | |
Programmed cell death and its clinical implications.
|
Score: 0.457 | |
Genetic control of programmed cell death in Drosophila.
|
Score: 0.454 | |
Targeted expression of ced-3 and Ice induces programmed cell death in Drosophila.
|
Score: 0.453 | |
sickle, a novel Drosophila death gene in the reaper/hid/grim region, encodes an IAP-inhibitory protein.
|
Score: 0.453 | |
dFADD, a novel death domain-containing adapter protein for the Drosophila caspase DREDD.
|
Score: 0.451 | |
Inactivation of Drosophila Apaf-1 related killer suppresses formation of polyglutamine aggregates and blocks polyglutamine pathogenesis.
|
Score: 0.451 | |
Execution mechanisms of programmed cell death by caspase (ICE/CED-3) family proteases.
|
Score: 0.450 | |
Multiple apoptotic caspase cascades are required in nonapoptotic roles for Drosophila spermatid individualization.
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Score: 0.446 | |
Evolution of TNF signaling mechanisms: JNK-dependent apoptosis triggered by Eiger, the Drosophila homolog of the TNF superfamily.
|
Score: 0.441 | |
Caspase-dependent inactivation of proteasome function during programmed cell death in Drosophila and man.
|
Score: 0.440 | |
Caspases: potential targets for regulating cell death.
|
Score: 0.439 | |
A balance between the diap1 death inhibitor and reaper and hid death inducers controls steroid-triggered cell death in Drosophila.
|
Score: 0.439 | |
The RHG motifs of Drosophila Reaper and Grim are important for their distinct cell death-inducing abilities.
|
Score: 0.438 | |
GH3, a novel proapoptotic domain in Drosophila Grim, promotes a mitochondrial death pathway.
|
Score: 0.436 | |
Drosophila p53 preserves genomic stability by regulating cell death.
|
Score: 0.431 | |
Mitochondrial apoptotic pathways induced by Drosophila programmed cell death regulators.
|
Score: 0.430 | |
Molecular mechanisms of cell death and phagocytosis in Drosophila.
|
Score: 0.427 | |
Analysis of programmed cell death and apoptosis in Drosophila.
|
Score: 0.424 | |
Proapoptotic activity of Caenorhabditis elegans CED-4 protein in Drosophila: implicated mechanisms for caspase activation.
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Score: 0.424 | |
Distinct cell killing properties of the Drosophila reaper, head involution defective, and grim genes.
|
Score: 0.423 | |
Control of the cell death pathway by Dapaf-1, a Drosophila Apaf-1/CED-4-related caspase activator.
|
Score: 0.422 | |
Cooperative functions of the reaper and head involution defective genes in the programmed cell death of Drosophila central nervous system midline cells.
|
Score: 0.422 | |
Migrate, differentiate, proliferate, or die: pleiotropic functions of an apical "apoptotic caspase".
|
Score: 0.421 | |
Drosophila sickle is a novel grim-reaper cell death activator.
|
Score: 0.420 | |
Programmed cell death in Drosophila.
|
Score: 0.420 | |
DECAY, a novel Drosophila caspase related to mammalian caspase-3 and caspase-7.
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Score: 0.420 | |
Distinct pathways mediate UV-induced apoptosis in Drosophila embryos.
|
Score: 0.419 | |
Viral modulators of cell death provide new links to old pathways.
|
Score: 0.419 | |
Apoptosis of ventricular myocytes: a means to an end.
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Score: 0.419 | |
Eggs over easy: cell death in the Drosophila ovary.
|
Score: 0.418 | |
Steroid regulation of programmed cell death during Drosophila development.
|
Score: 0.417 | |
Caspase inhibitors.
|
Score: 0.417 | |
The apical caspase dronc governs programmed and unprogrammed cell death in Drosophila.
|
Score: 0.417 | |
Aven, a novel inhibitor of caspase activation, binds Bcl-xL and Apaf-1.
|
Score: 0.416 | |
Genes that induce apoptosis: transcriptional regulation in identified, doomed neurons of the Drosophila CNS.
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Score: 0.416 | |
The control of apoptosis in Drosophila.
|
Score: 0.416 | |
Targeted disruption of caspase genes in mice: what they tell us about the functions of individual caspases in apoptosis.
|
Score: 0.414 | |
Genome-wide analyses of steroid- and radiation-triggered programmed cell death in Drosophila.
|
Score: 0.414 | |
Guardian ancestry: fly p53 and damage-inducible apoptosis.
|
Score: 0.413 | |
Understanding IAP function and regulation: a view from Drosophila.
|
Score: 0.413 | |
Mutational analysis of the Caenorhabditis elegans cell-death gene ced-3.
|
Score: 0.413 | |
STRICA, a novel Drosophila melanogaster caspase with an unusual serine/threonine-rich prodomain, interacts with DIAP1 and DIAP2.
|
Score: 0.411 | |
Identification of a Drosophila melanogaster ICE/CED-3-related protease, drICE.
|
Score: 0.411 | |
Roles of caspases in the programmed cell death of motoneurons in vivo.
|
Score: 0.411 | |
The Drosophila melanogaster Apaf-1 homologue ARK is required for most, but not all, programmed cell death.
|
Score: 0.410 | |
Cell migration and programmed cell death of Drosophila germ cells.
|
Score: 0.409 | |
The role of Apaf-1 in programmed cell death: from worm to tumor.
|
Score: 0.405 | |
Apoptosis: checkpoint at the mitochondrial frontier.
|
Score: 0.405 | |
Cell ablation by ectopic expression of cell death genes, ced-3 and Ice, in Drosophila.
|
Score: 0.404 | |
Apoptosis induced by Drosophila reaper and grim in a human system. Attenuation by inhibitor of apoptosis proteins (cIAPs).
|
Score: 0.404 | |
Regulation and execution of apoptosis during Drosophila development.
|
Score: 0.404 | |
Apoptosis in Drosophila: neither fish nor fowl (nor man, nor worm).
|
Score: 0.402 | |
Induction of apoptosis by Drosophila reaper, hid and grim through inhibition of IAP function.
|
Score: 0.402 | |
Apoptosomes: engines for caspase activation.
|
Score: 0.401 | |
Caspases: the proteases of the apoptotic pathway.
|
Score: 0.397 | |
Mechanisms and genes of cellular suicide.
|
Score: 0.397 | |
Drosophila p53 binds a damage response element at the reaper locus.
|
Score: 0.396 | |
Programmed cell death in the nematode C. elegans.
|
Score: 0.396 | |
A pathway of signals regulating effector and initiator caspases in the developing Drosophila eye.
|
Score: 0.395 | |
Caspase activation finds fertile ground.
|
Score: 0.395 | |
Three-dimensional structure of a double apoptosome formed by the Drosophila Apaf-1 related killer.
|
Score: 0.395 | |
Programmed cell death and the caspases.
|
Score: 0.395 | |
Drosophila Bruce can potently suppress Rpr- and Grim-dependent but not Hid-dependent cell death.
|
Score: 0.395 | |
Genetic and hormonal regulation of the death of peptidergic neurons in the Drosophila central nervous system.
|
Score: 0.394 | |
Programmed cell death and aging in Drosophila melanogaster.
|
Score: 0.393 | |
Genetic control of programmed cell death in the nematode Caenorhabditis elegans.
|
Score: 0.393 | |
[Regulation of caspase activity in apoptosis]
|
Score: 0.392 | |
The role of caspases in apoptosis.
|
Score: 0.392 | |
Ecdysone-mediated up-regulation of the effector caspase DRICE is required for hormone-dependent apoptosis in Drosophila cells.
|
Score: 0.392 | |
Controlling apoptosis by inhibition of caspases.
|
Score: 0.390 | |
Caspases: the executioners of apoptosis.
|
Score: 0.388 | |
Morgue mediates apoptosis in the Drosophila melanogaster retina by promoting degradation of DIAP1.
|
Score: 0.388 | |
Biochemical and genetic interactions between Drosophila caspases and the proapoptotic genes rpr, hid, and grim.
|
Score: 0.387 | |
Characterization of the Drosophila caspase, DAMM.
|
Score: 0.385 | |
Programmed cell death. A rich harvest.
|
Score: 0.385 | |
Eggs to die for: cell death during Drosophila oogenesis.
|
Score: 0.384 | |
Death receptors and caspases: role in lymphocyte proliferation, cell death, and autoimmunity.
|
Score: 0.383 | |
Genetic control of programmed cell death in the nematode C. elegans.
|
Score: 0.382 | |
More than cell death: caspases and caspase inhibitors on the move.
|
Score: 0.381 | |
The Drosophila inhibitor of apoptosis D-IAP1 suppresses cell death induced by the caspase drICE.
|
Score: 0.381 | |
Programmed cell deaths. Apoptosis and alternative deathstyles.
|
Score: 0.380 | |
Regulators of IAP function: coming to grips with the grim reaper.
|
Score: 0.380 | |
Regulatory roles of JNK in programmed cell death.
|
Score: 0.380 | |
Cell killing by the Drosophila gene reaper.
|
Score: 0.380 | |
Serial killers: ordering caspase activation events in apoptosis.
|
Score: 0.379 | |
Modulation of cell death by Bcl-XL through caspase interaction.
|
Score: 0.379 | |
Mammalian caspases: structure, activation, substrates, and functions during apoptosis.
|
Score: 0.379 | |
Pathways of apoptosis and importance in development.
|
Score: 0.379 | |
Death to flies: Drosophila as a model system to study programmed cell death.
|
Score: 0.378 | |
Rpr- and hid-driven cell death in Drosophila photoreceptors.
|
Score: 0.378 | |
Activation of the reaper gene during ectopic cell killing in Drosophila.
|
Score: 0.378 | |
Activators, deactivators and deactivated activators.
|
Score: 0.377 | |
Induction of apoptosis in fibroblasts by IL-1 beta-converting enzyme, a mammalian homolog of the C. elegans cell death gene ced-3.
|
Score: 0.377 | |
Caspases function in autophagic programmed cell death in Drosophila.
|
Score: 0.377 | |
Programmed cell death takes flight: genetic and genomic approaches to gene discovery in Drosophila.
|
Score: 0.376 | |
Steroid-triggered death by autophagy.
|
Score: 0.376 | |
CDK inhibitors suppress apoptosis induced by chemicals and by excessive expression of a cell death gene, reaper, in Drosophila cells.
|
Score: 0.376 | |
Mechanisms mediating caspase activation in cell death.
|
Score: 0.376 | |
Looking beneath the surface: the cell death pathway of Fas/APO-1 (CD95).
|
Score: 0.375 | |
Detection of apoptosis in Drosophila.
|
Score: 0.375 | |
The kinder side of killer proteases: caspase activation contributes to neuroprotection and CNS remodeling.
|
Score: 0.375 | |
Death without caspases, caspases without death.
|
Score: 0.374 | |
The Drosophila caspase inhibitor DIAP1 is essential for cell survival and is negatively regulated by HID.
|
Score: 0.373 | |
Buffy, a Drosophila Bcl-2 protein, has anti-apoptotic and cell cycle inhibitory functions.
|
Score: 0.373 | |
Role of programmed cell death in development.
|
Score: 0.373 | |
Regulation of apoptosis by Bcl-2 family proteins.
|
Score: 0.372 | |
Apoptosis and autoimmune disease.
|
Score: 0.372 | |
[Ice/ced-3 family gene and apoptosis]
|
Score: 0.372 | |
Caspase inhibitors in prevention of apoptosis.
|
Score: 0.371 | |
Baculovirus p35 prevents developmentally programmed cell death and rescues a ced-9 mutant in the nematode Caenorhabditis elegans.
|
Score: 0.370 | |
Caspase activation, inhibition, and reactivation: a mechanistic view.
|
Score: 0.370 | |
Caspases, the enemy within, and their role in oxidative stress-induced apoptosis of inner ear sensory cells.
|
Score: 0.370 | |
The ins and outs of programmed cell death during C. elegans development.
|
Score: 0.369 | |
The mitochondrial ARTS protein promotes apoptosis through targeting XIAP.
|
Score: 0.368 | |
Autophagy occurs upstream or parallel to the apoptosome during histolytic cell death.
|
Score: 0.368 | |
Pathways to caspase activation.
|
Score: 0.367 | |
Caspase-9, Bcl-XL, and Apaf-1 form a ternary complex.
|
Score: 0.367 | |
Caspase pathways, neuronal apoptosis, and CNS injury.
|
Score: 0.366 | |
drICE is an essential caspase required for apoptotic activity in Drosophila cells.
|
Score: 0.366 | |
Molecular genetics of cell death in the nematode Caenorhabditis elegans.
|
Score: 0.365 | |
Mechanisms of apoptosis in the heart.
|
Score: 0.365 | |
Debcl, a proapoptotic Bcl-2 homologue, is a component of the Drosophila melanogaster cell death machinery.
|
Score: 0.364 | |
Biochemical pathways of caspase activation during apoptosis.
|
Score: 0.364 | |
ICE, neuronal apoptosis and neurodegeneration.
|
Score: 0.364 | |
Non-apoptotic functions of caspases in cellular proliferation and differentiation.
|
Score: 0.364 | |
Programmed cell death: many ways for cells to die decently.
|
Score: 0.363 | |
DIAP1 suppresses ROS-induced apoptosis caused by impairment of the selD/sps1 homolog in Drosophila.
|
Score: 0.363 | |
Genetic approaches for the identification of apoptotic components.
|
Score: 0.363 | |
Activation of distinct caspase-like proteases by Fas and reaper in Drosophila cells.
|
Score: 0.361 | |
E93 directs steroid-triggered programmed cell death in Drosophila.
|
Score: 0.361 | |
Identification of a caspase-9 substrate and detection of its cleavage in programmed cell death during mouse development.
|
Score: 0.361 | |
Proteases for cell suicide: functions and regulation of caspases.
|
Score: 0.361 | |
2001 Warkany lecture: to die or not to die, the role of apoptosis in normal and abnormal mammalian development.
|
Score: 0.361 | |
Apoptosis in the heart: about programmed cell death and survival.
|
Score: 0.361 | |
The molecular mechanisms of neuronal apoptosis.
|
Score: 0.360 | |
Mechanisms of programmed cell death in the developing brain.
|
Score: 0.359 | |
Caspase-activation pathways in apoptosis and immunity.
|
Score: 0.359 | |
The Drosophila bcl-2 family member dBorg-1 functions in the apoptotic response to UV-irradiation.
|
Score: 0.359 | |
Programmed cell death in plant disease: the purpose and promise of cellular suicide.
|
Score: 0.359 | |
Drosophila caspase DRONC is required for specific developmental cell death pathways and stress-induced apoptosis.
|
Score: 0.359 | |
Argos induces programmed cell death in the developing Drosophila eye by inhibition of the Ras pathway.
|
Score: 0.358 | |
Caenorhabditis elegans anti-apoptotic gene ced-9 prevents ced-3-induced cell death in Drosophila cells.
|
Score: 0.358 | |
Ras promotes cell survival in Drosophila by downregulating hid expression.
|
Score: 0.357 | |
Advances and controversies in the study of programmed cell death/apoptosis in the development of and therapy for cancer.
|
Score: 0.357 | |
Identification and characterization of a novel mammalian caspase with proapoptotic activity.
|
Score: 0.356 | |
Activation of caspases by death receptors.
|
Score: 0.356 | |
Steroid regulation of autophagic programmed cell death during development.
|
Score: 0.355 | |
ICE-like proteases execute the neuronal death program.
|
Score: 0.355 | |
Ionizing radiation-induced, Bax-mediated cell death is dependent on activation of cysteine and serine proteases.
|
Score: 0.355 | |
Prevention of programmed cell death in Caenorhabditis elegans by human bcl-2.
|
Score: 0.355 | |
Apoptosis and its relevance in cancer therapy.
|
Score: 0.354 | |
Mechanisms of apoptosis.
|
Score: 0.354 | |
Distinct promoter regions regulate spatial and temporal expression of the Drosophila caspase dronc.
|
Score: 0.354 | |
Nitric oxide donors inhibit formation of the Apaf-1/caspase-9 apoptosome and activation of caspases.
|
Score: 0.354 | |
Caspase-dependent apoptotic pathways in CNS injury.
|
Score: 0.354 | |
Apoptosis in the central nervous system: Mechanisms and protective strategies.
|
Score: 0.354 | |
AP-1, but not NF-kappa B, is required for efficient steroid-triggered cell death in Drosophila.
|
Score: 0.354 | |
Yeast as a model to study apoptosis?
|
Score: 0.354 | |
Does the plant mitochondrion integrate cellular stress and regulate programmed cell death?
|
Score: 0.354 | |
The Drosophila caspase DRONC is regulated by DIAP1.
|
Score: 0.354 | |
Binary cell death decision regulated by unequal partitioning of Numb at mitosis.
|
Score: 0.354 | |
A Bax/Bak-independent mitochondrial death pathway triggered by Drosophila Grim GH3 domain in mammalian cells.
|
Score: 0.354 | |
Mechanisms of apoptosis: integration of genetic, biochemical, and cellular indicators.
|
Score: 0.353 | |
Bcl-2 and Bax mammalian regulators of apoptosis are functional in Drosophila.
|
Score: 0.353 | |
Drosophila morgue and the intersection between protein ubiquitination and programmed cell death.
|
Score: 0.353 | |
Caspase activity is not sufficient to execute cell death.
|
Score: 0.353 | |
The Drosophila gene hid is a direct molecular target of Ras-dependent survival signaling.
|
Score: 0.353 | |
Genetics of programmed cell death in C. elegans: past, present and future.
|
Score: 0.352 | |
Characterization of reaper- and FADD-induced apoptosis in a lepidopteran cell line.
|
Score: 0.352 | |
Caspase-independent programmed cell death with necrotic morphology.
|
Score: 0.352 | |
Programmed cell death in Caenorhabditis elegans.
|
Score: 0.352 | |
Steroid regulated programmed cell death during Drosophila metamorphosis.
|
Score: 0.351 | |
The two cytochrome c species, DC3 and DC4, are not required for caspase activation and apoptosis in Drosophila cells.
|
Score: 0.351 | |
Structure, expression, and function of the Xenopus laevis caspase family.
|
Score: 0.351 | |
Direct regulation of egl-1 and of programmed cell death by the Hox protein MAB-5 and by CEH-20, a C. elegans homolog of Pbx1.
|
Score: 0.350 | |
Life's smile, death's grin: vital functions of apoptosis-executing proteins.
|
Score: 0.350 | |
Drosophila MyD88 is an adapter in the Toll signaling pathway.
|
Score: 0.350 | |
Cell death in C. elegans: molecular insights into mechanisms conserved between nematodes and mammals.
|
Score: 0.350 | |
Genetic control of programmed cell death in Drosophila melanogaster.
|
Score: 0.350 | |
Caspases: key players in programmed cell death.
|
Score: 0.349 | |
Caspase-14 is a novel developmentally regulated protease.
|
Score: 0.349 | |
The DIAP1 RING finger mediates ubiquitination of Dronc and is indispensable for regulating apoptosis.
|
Score: 0.349 | |
Evolutionary conservation of a genetic pathway of programmed cell death.
|
Score: 0.348 | |
Bcl-2 family members do not inhibit apoptosis by binding the caspase activator Apaf-1.
|
Score: 0.348 | |
Identification of X-linked genes required for migration and programmed cell death of Drosophila melanogaster germ cells.
|
Score: 0.348 | |
Caspases: an ancient cellular sword of Damocles.
|
Score: 0.348 | |
Apoptosis and caspases.
|
Score: 0.347 | |
RNA expression bcl-w, a new related protein Bcl-2 family, and caspase-3 in isolated sertoli cells from pre-pubertal rat testes.
|
Score: 0.347 | |
Mechanism of action of Drosophila Reaper in mammalian cells: Reaper globally inhibits protein synthesis and induces apoptosis independent of mitochondrial permeability.
|
Score: 0.347 | |
Progress in understanding the Drosophila dnc locus.
|
Score: 0.347 | |
Role of programmed cell death in patterning the Drosophila antennal arista.
|
Score: 0.346 | |
Identification of rTid-1, the rat homologue of the drosophila tumor suppressor l(2)tid gene.
|
Score: 0.346 | |
A cloning method to identify caspases and their regulators in yeast: identification of Drosophila IAP1 as an inhibitor of the Drosophila caspase DCP-1.
|
Score: 0.345 | |
The Drosophila caspase DRONC is required for metamorphosis and cell death in response to irradiation and developmental signals.
|
Score: 0.345 | |
Reaper-induced dissociation of a Scythe-sequestered cytochrome c-releasing activity.
|
Score: 0.345 | |
Apoptosis in neuronal cells: role of caspases.
|
Score: 0.345 | |
Caenorhabditis elegans gene ced-9 protects cells from programmed cell death.
|
Score: 0.344 | |
Prevention of apoptosis by a baculovirus gene during infection of insect cells.
|
Score: 0.344 | |
[Molecular mechanisms of apoptosis in the immune system]
|
Score: 0.344 | |
Genetic analysis of protein kinase B (AKT) in Drosophila.
|
Score: 0.344 | |
Liver toxicity and apoptosis: role of TGF-beta1, cytochrome c and the apoptosome.
|
Score: 0.344 | |
Signals and susceptibility to programmed death in b cells.
|
Score: 0.344 | |
Programmed cell death during Drosophila embryogenesis.
|
Score: 0.344 | |
Caspases: cellular demolition experts.
|
Score: 0.344 | |
Lozenge directly activates argos and klumpfuss to regulate programmed cell death.
|
Score: 0.343 | |
Inhibition of myocardial apoptosis as a therapeutic target in cardiovascular disease prevention: focus on caspase inhibition.
|
Score: 0.343 | |
Apoptosis or programmed cell death.
|
Score: 0.343 | |
The role of androgen in the regulation of programmed cell death/apoptosis in normal and malignant prostatic tissue.
|
Score: 0.342 | |
The C. elegans cell death gene ced-3 encodes a protein similar to mammalian interleukin-1 beta-converting enzyme.
|
Score: 0.342 | |
DRONC, an ecdysone-inducible Drosophila caspase.
|
Score: 0.342 | |
Ecdysone-induced expression of the caspase DRONC during hormone-dependent programmed cell death in Drosophila is regulated by Broad-Complex.
|
Score: 0.342 | |
Characterization of a mammalian cell death gene Nedd2.
|
Score: 0.341 | |
A SAGE approach to discovery of genes involved in autophagic cell death.
|
Score: 0.341 | |
Role of caspases in renal tubular epithelial cell injury.
|
Score: 0.341 | |
Cell death independent of caspases: a review.
|
Score: 0.340 | |
Eukaryotic transcription activation: right on target.
|
Score: 0.340 | |
Caspases: pharmacological manipulation of cell death.
|
Score: 0.340 | |
[Inhibition of apoptosis by a baculovirus p35 gene]
|
Score: 0.340 | |
The Drosophila sterile-20 kinase slik controls cell proliferation and apoptosis during imaginal disc development.
|
Score: 0.340 | |
DRP-1-mediated mitochondrial fragmentation during EGL-1-induced cell death in C. elegans.
|
Score: 0.340 | |
The role of programmed cell death in Plasmodium-mosquito interactions.
|
Score: 0.339 | |
Programmed cell death in fission yeast.
|
Score: 0.339 | |
Induction of apoptosis by the mouse Nedd2 gene, which encodes a protein similar to the product of the Caenorhabditis elegans cell death gene ced-3 and the mammalian IL-1 beta-converting enzyme.
|
Score: 0.339 | |
Reaper is regulated by IAP-mediated ubiquitination.
|
Score: 0.338 | |
Properties of the caspases.
|
Score: 0.338 | |
Hid, Rpr and Grim negatively regulate DIAP1 levels through distinct mechanisms.
|
Score: 0.338 | |
Programmed cell death.
|
Score: 0.338 | |
A screen for mutations that suppress the phenotype of Drosophila armadillo, the beta-catenin homolog.
|
Score: 0.338 | |
Compensatory proliferation induced by cell death in the Drosophila wing disc requires activity of the apical cell death caspase Dronc in a nonapoptotic role.
|
Score: 0.337 | |
Death receptor-induced activation of initiator caspase 8 is antagonized by serine/threonine kinase PAK4.
|
Score: 0.337 | |
Caspase-independent cell death.
|
Score: 0.337 | |
Apoptosis without caspases: an inefficient molecular guillotine?
|
Score: 0.337 | |
Localization, regulation and possible consequences of apoptotic protease-activating factor-1 (Apaf-1) expression in granulosa cells of the mouse ovary.
|
Score: 0.336 | |
The central executioners of apoptosis: caspases or mitochondria?
|
Score: 0.336 | |
Apoptin-induced cell death is modulated by Bcl-2 family members and is Apaf-1 dependent.
|
Score: 0.336 | |
Cellular inhibitor of apoptosis 1 and 2 are ubiquitin ligases for the apoptosis inducer Smac/DIABLO.
|
Score: 0.336 | |
Apoptosis: a process with a (beta)NAC for complexity.
|
Score: 0.336 | |
Caspase-9 and APAF-1 form an active holoenzyme.
|
Score: 0.336 | |