FRISC: The Faculty Research Interests Science Comparator

Robert J. Alpern, M.D.
Professor of Internal Medicine
Integrative
Biology
Office: 214-648- 2509
FAX: 214-648- 8955
Email: robert.alpern@email.swmed.edu

New This Month | New This Year | Abstract | Selected Publications | FRISC Statistics Results - FULL MEDLINE:

Acute regulation of proximal tubule apical membrane Na/H exchanger NHE-3: role of phosphorylation, protein trafficking, and regulatory factors.
O W Moe
J Am Soc Nephrol 1999 Nov; 10(11)2412-25.

Score: 0.710
Physiology and molecular biology of the renal Na/H antiporter.
R Krapf
Klin Wochenschr 1989 Sep; 67(17)847-51.

Score: 0.703
Effects of subchronic exposures to concentrated ambient particles (CAPs) in mice. III. Acute and chronic effects of CAPs on heart rate, heart-rate fluctuation, and body temperature.
Jing-Shiang Hwang ... Lung Chi Chen
Inhal Toxicol 2005 Apr; 17(4-5)199-207.

Score: 0.662
The Na+/H+ exchanger gene family.
Gerhard Burckhardt ... Corinna Helmle-Kolb
J Nephrol 2002 Mar-Apr; 15 Suppl 5()S3-21.

Score: 0.644
Acute inhibition of Na/H exchanger NHE-3 by cAMP. Role of protein kinase a and NHE-3 phosphoserines 552 and 605.
H Zhao ... O W Moe
J Biol Chem 1999 Feb; 274(7)3978-87.

Score: 0.627
Effects of subchronic exposures to concentrated ambient particles (CAPs) in mice. IV. Characterization of acute and chronic effects of ambient air fine particulate matter exposures on heart-rate variability.
Lung Chi Chen ... Jing-Shiang Hwang
Inhal Toxicol 2005 Apr; 17(4-5)209-16.

Score: 0.617
Effect of glucocorticoids on renal cortical NHE-3 and NHE-1 mRNA.
M Baum ... R J Alpern
Am J Physiol 1994 Sep; 267(3 Pt 2)F437-42.

Score: 0.601
Activation of protein kinase A acutely inhibits and phosphorylates Na/H exchanger NHE-3.
O W Moe ... Y Yamaji
J Clin Invest 1995 Nov; 96(5)2187-94.

Score: 0.600
Dual mechanisms of regulation of Na/H exchanger NHE-3 by parathyroid hormone in rat kidney.
L Fan ... O W Moe
J Biol Chem 1999 Apr; 274(16)11289-95.

Score: 0.594
Coordinated down-regulation of NBC-1 and NHE-3 in sodium and bicarbonate loading.
H Amlal ... M Soleimani
Kidney Int 2001 Nov; 60(5)1824-36.

Score: 0.574
Expression of NHE-3 in the apical membrane of rat renal proximal tubule and thick ascending limb.
M Amemiya ... O W Moe
Kidney Int 1995 Oct; 48(4)1206-15.

Score: 0.550
Inhibition of glycosylation decreases Na+/H+ exchange activity, blocks NHE-3 transport to the membrane, and increases NHE-3 mRNA expression in LLC-PK1 cells.
M Soleimani ... J H Dominguez
J Lab Clin Med 1996 Jun; 127(6)565-73.

Score: 0.539
Characterization of acute inhibition of Na/H exchanger NHE-3 by dopamine in opossum kidney cells.
M R Wiederkehr ... O W Moe
Kidney Int 2001 Jan; 59(1)197-209.

Score: 0.530
Na+/H+ exchange activity and NHE-3 expression in renal tubules from the spontaneously hypertensive rat.
Michael S LaPointe ... Daniel Batlle
Kidney Int 2002 Jul; 62(1)157-65.

Score: 0.529
Na+/H+ antiport: modulation by ATP and role in cell volume regulation.
N Demaurex ... S Grinstein
J Exp Biol 1994 Nov; 196()389-404.

Score: 0.522
Regulation of proximal tubule transport by angiotensin II.
A Quan ... M Baum
Semin Nephrol 1997 Sep; 17(5)423-30.

Score: 0.521
Effects of subchronic exposures to concentrated ambient particles (CAPs) in mice. VI. Gene expression in heart and lung tissue.
Albert Gunnison ... Lung Chi Chen
Inhal Toxicol 2005 Apr; 17(4-5)225-33.

Score: 0.515
Glucocorticoids regulate NHE-3 transcription in OKP cells.
M Baum ... O W Moe
Am J Physiol 1996 Jan; 270(1 Pt 2)F164-9.

Score: 0.514
Renal transplantation modulates expression and function of receptors and transporters of rat proximal tubules.
Ana Velic ... Gert Gabriëls
J Am Soc Nephrol 2004 Apr; 15(4)967-77.

Score: 0.511
H+ and HCO3- transporters in the medullary thick ascending limb of the kidney: molecular mechanisms, function and regulation.
M Paillard
Kidney Int Suppl 1998 Apr; 65()S36-41.

Score: 0.510
Use of transgenic animals to study renal acid-base transport.
Tong Wang ... Peter S Aronson
J Nephrol 2002 Mar-Apr; 15 Suppl 5()S151-60.

Score: 0.508
Adaptation of NHE-3 in the rat thick ascending limb: effects of high sodium intake and metabolic alkalosis.
K Laghmani ... P Borensztein
Am J Physiol 1999 Jan; 276(1 Pt 2)F18-26.

Score: 0.507
An apical membrane Na+/H+ exchanger isoform, NHE-3, is present in the rat epididymal epithelium.
K Kaunisto ... H Rajaniemi
Pflugers Arch 2001 May; 442(2)230-6.

Score: 0.503
Overexpression of csk inhibits acid-induced activation of NHE-3.
Y Yamaji ... R J Alpern
Proc Natl Acad Sci U S A 1995 Jul; 92(14)6274-8.

Score: 0.495
Targeted proteomic profiling of renal Na(+) transporter and channel abundances in angiotensin II type 1a receptor knockout mice.
Heddwen L Brooks ... Mark A Knepper
Hypertension 2002 Feb; 39(2 Pt 2)470-3.

Score: 0.494
Effect of long-term hyperosmolality on the Na+/H+ exchanger isoform NHE-3 in LLC-PK1 cells.
M Soleimani ... D W Good
Kidney Int 1998 Feb; 53(2)423-31.

Score: 0.493
The cytochrome P-450 inhibitor cobalt chloride prevents inhibition of renal Na,K-ATPase and redistribution of apical NHE-3 during acute hypertension.
Y B Zhang ... A A McDonough
J Am Soc Nephrol 1998 Apr; 9(4)531-7.

Score: 0.492
Expression and cell-specific and membrane-specific localization of NHE-3 in the human and guinea pig upper gastrointestinal tract.
H Kulaksiz ... Y Cetin
Cell Tissue Res 2001 Mar; 303(3)337-43.

Score: 0.487
Renal Na/H exchanger NHE-3 and Na-PO4 cotransporter NaPi-2 protein expression in glucocorticoid excess and deficient states.
J Loffing ... O W Moe
J Am Soc Nephrol 1998 Sep; 9(9)1560-7.

Score: 0.485
NHE-3 isoform of the Na+/H+ exchanger in human gallbladder. Localization of specific mRNA by in situ hybridization.
V Silviani ... A Gerolami
J Hepatol 1997 Jun; 26(6)1281-6.

Score: 0.484
Effect of high osmolality on Na+/H+ exchange in renal proximal tubule cells.
M Soleimani ... E B Chang
J Biol Chem 1994 Jun; 269(22)15613-8.

Score: 0.483
Functional characterization of three isoforms of the Na+/H+ exchanger stably expressed in Chinese hamster ovary cells. ATP dependence, osmotic sensitivity, and role in cell proliferation.
A Kapus ... J Orlowski
J Biol Chem 1994 Sep; 269(38)23544-52.

Score: 0.483
Angiotensin II and renal tubular ion transport.
Patricia Valles ... Daniel Batlle
ScientificWorldJournal 2005 Aug; 5()680-90.

Score: 0.482
Red cell Na+/Li+ countertransport and Na+/H+ exchanger isoforms in human proximal tubules.
L L Ng ... S J Carr
Kidney Int 2000 Jul; 58(1)229-35.

Score: 0.478
Regulation of renal bicarbonate reabsorption by extracellular volume.
N A Kurtzman
J Clin Invest 1970 Mar; 49(3)586-95.

Score: 0.473
Increased proximal tubule NHE-3 and H+-ATPase activities in spontaneously hypertensive rats.
K L Aldred ... E Eitle
J Hypertens 2000 May; 18(5)623-8.

Score: 0.472
HCO-3 reabsorption in renal collecting duct of NHE-3-deficient mouse: a compensatory response.
S Nakamura ... M Soleimani
Am J Physiol 1999 Jun; 276(6 Pt 2)F914-21.

Score: 0.469
Acid incubation increases NHE-3 mRNA abundance in OKP cells.
M Amemiya ... R J Alpern
Am J Physiol 1995 Jul; 269(1 Pt 1)C126-33.

Score: 0.469
Chronic metabolic acidosis enhances NHE-3 protein abundance and transport activity in the rat thick ascending limb by increasing NHE-3 mRNA.
K Laghmani ... M Paillard
J Clin Invest 1997 Jan; 99(1)24-30.

Score: 0.468
Cloning and sequencing of a rabbit cDNA encoding an intestinal and kidney-specific Na+/H+ exchanger isoform (NHE-3).
C M Tse ... M Donowitz
J Biol Chem 1992 May; 267(13)9340-6.

Score: 0.466
Formate-stimulated NaCl absorption in the proximal tubule is independent of the pendrin protein.
Lawrence P Karniski ... Peter S Aronson
Am J Physiol Renal Physiol 2002 Nov; 283(5)F952-6.

Score: 0.465
Kidney cortex cells derived from SV40 transgenic mice retain intrinsic properties of polarized proximal tubule cells.
C Chalumeau ... J Poggioli
Kidney Int 1999 Aug; 56(2)559-70.

Score: 0.464
Endothelins: renal tubule synthesis and actions.
D E Kohan
Clin Exp Pharmacol Physiol 1996 Apr; 23(4)337-44.

Score: 0.464
Renal regulation of extracellular fluid volume and osmolality.
C Yucha ... M Keen
ANNA J 1996 Oct; 23(5)487-95; quiz 496-7.

Score: 0.464
Comparative roles of the renal apical sodium transport systems in blood pressure control.
P Meneton
J Am Soc Nephrol 2000 Nov; 11 Suppl 16()S135-9.

Score: 0.464
Renal regulation of extracellular fluid volume and osmolality.
Lori Candela ... Carolyn Yucha
Nephrol Nurs J 2004 Jul-Aug; 31(4)397-404, 444; quiz 405-6.

Score: 0.464
Phenotype resembling Gitelman's syndrome in mice lacking the apical Na+-Cl- cotransporter of the distal convoluted tubule.
P J Schultheis ... G E Shull
J Biol Chem 1998 Oct; 273(44)29150-5.

Score: 0.461
Regulation of proximal reabsorption by effective arterial blood volume.
D W Seldin ... R J Alpern
Semin Nephrol 1991 Mar; 11(2)212-9.

Score: 0.461
Glucocorticoids enhance the expression of the basolateral Na+:HCO3- cotransporter in renal proximal tubules.
R Ali ... M Soleimani
Kidney Int 2000 Mar; 57(3)1063-71.

Score: 0.460
Na+/H+ exchanger subtypes in the renal tubule: function and regulation in physiology and disease.
M Paillard
Exp Nephrol 1997 Jul-Aug; 5(4)277-84.

Score: 0.456
Regulation of extracellular fluid volume and osmolality.
P H Abbrecht
Ann Biomed Eng 1980 ; 8(4-6)461-72.

Score: 0.456
Endothelin-1 chronically inhibits Na/H exchanger-3 in ET(B)-overexpressing OKP cells.
T S Chu ... B S Hsieh
Biochem Biophys Res Commun 2000 May; 271(3)807-11.

Score: 0.453
Transient expression of Na+/H+ exchanger isoform NHE-2 in LLC-PK1 cells: inhibition of endogenous NHE-3 and regulation by hypertonicity.
G Singh ... M Soleimani
J Membr Biol 1996 Jun; 151(3)261-8.

Score: 0.451
Bicarbonate reabsorption and NHE-3 expression: abundance and activity are increased in Henle's loop of remnant rats.
Giovambattista Capasso ... Natale G De Santo
Kidney Int 2002 Dec; 62(6)2126-35.

Score: 0.446
Ischemic-reperfusion injury in the kidney: overexpression of colonic H+-K+-ATPase and suppression of NHE-3.
Z Wang ... M Soleimani
Kidney Int 1997 Apr; 51(4)1106-15.

Score: 0.444
Altered expression of the Na+/H+ exchanger isoform-3 in experimental colitis: effect of garlic.
I Khan ... M Ali
Mol Cell Biochem 1999 Oct; 200(1-2)77-84.

Score: 0.444
Renal salt wasting in mice lacking NHE3 Na+/H+ exchanger but not in mice lacking NHE2.
C Ledoussal ... G E Shull
Am J Physiol Renal Physiol 2001 Oct; 281(4)F718-27.

Score: 0.443
Altered expression of Na transporters NHE-3, NaPi-II, Na-K-ATPase, BSC-1, and TSC in CRF rat kidneys.
T H Kwon ... S Nielsen
Am J Physiol 1999 Aug; 277(2 Pt 2)F257-70.

Score: 0.443
Update on renal acidification: a physiological view.
G Capasso ... N G De Santo
Miner Electrolyte Metab 1997 ; 23(3-6)243-8.

Score: 0.441
Profiling of renal tubule Na+ transporter abundances in NHE3 and NCC null mice using targeted proteomics.
H L Brooks ... M A Knepper
J Physiol 2001 Feb; 530(Pt 3)359-66.

Score: 0.441
Dietary NaCl modulates Na(+)-H+ antiporter activity in renal cortical apical membrane vesicles.
O W Moe ... R J Alpern
Am J Physiol 1991 Jan; 260(1 Pt 2)F130-7.

Score: 0.441
Activation/deactivation of renal Na+,K(+)-ATPase: a final common pathway for regulation of natriuresis.
A Aperia ... P Greengard
FASEB J 1994 Apr; 8(6)436-9.

Score: 0.440
Demonstration of a functional apical sodium hydrogen exchanger in isolated rat gastric glands.
Philipp Kirchhoff ... John P Geibel
Am J Physiol Gastrointest Liver Physiol 2003 Dec; 285(6)G1242-8.

Score: 0.438
Role of ion exchangers in mediating NaCl transport in the proximal tubule.
P S Aronson
Kidney Int 1996 Jun; 49(6)1665-70.

Score: 0.437
Na+/H+ exchangers, NHE-1 and NHE-3, of rat intestine. Expression and localization.
C Bookstein ... E B Chang
J Clin Invest 1994 Jan; 93(1)106-13.

Score: 0.437
Dominant negative c-Src inhibits angiotensin II induced activation of NHE3 in OKP cells.
H Tsuganezawa ... R J Alpern
Kidney Int 1998 Aug; 54(2)394-8.

Score: 0.436
Angiotensin II: a powerful controller of sodium transport in the early proximal tubule.
M G Cogan
Hypertension 1990 May; 15(5)451-8.

Score: 0.436
Role of renal tissue angiotensin II in proximal tubule function.
William J Welch
Am J Physiol Renal Physiol 2005 Mar; 288(3)F443-4.

Score: 0.436
Regulatory and functional interaction of vasoactive factors in the kidney and extracellular pH.
Sharma S Prabhakar
Kidney Int 2004 Nov; 66(5)1742-54.

Score: 0.434
A possible molecular basis of natriuresis during ischemic-reperfusion injury in the kidney.
Z Wang ... M Soleimani
J Am Soc Nephrol 1998 Apr; 9(4)605-13.

Score: 0.433
Angiotensinogen gene null-mutant mice lack homeostatic regulation of glomerular filtration and tubular reabsorption.
S Okubo ... I Ichikawa
Kidney Int 1998 Mar; 53(3)617-25.

Score: 0.429
The plasma membrane sodium-hydrogen exchanger and its role in physiological and pathophysiological processes.
R L Mahnensmith ... P S Aronson
Circ Res 1985 Jun; 56(6)773-88.

Score: 0.428
Uroguanylin knockout mice have increased blood pressure and impaired natriuretic response to enteral NaCl load.
John N Lorenz ... Mitchell B Cohen
J Clin Invest 2003 Oct; 112(8)1244-54.

Score: 0.427
Localization of the Na+/H+ exchanger isoform NHE-3 in rabbit and canine kidney.
M Soleimani ... E B Chang
Biochim Biophys Acta 1994 Oct; 1195(1)89-95.

Score: 0.426
Selective suppression of renal Na+/H+ exchanger isoform-3 by prolonged stimulation of rats with adrenocorticotropic hormone.
I Khan ... B Cheng
Endocrine 2001 Dec; 16(3)189-94.

Score: 0.424
Control of blood and extracellular volume.
A W Cowley ... R J Roman
Baillieres Clin Endocrinol Metab 1989 Aug; 3(2)331-69.

Score: 0.423
Albumin and glucose effects on cell growth parameters, albumin uptake and Na(+)/H(+)-exchanger Isoform 3 in OK cells.
Karina Drumm ... Carol Pollock
Cell Physiol Biochem 2003 ; 13(4)199-206.

Score: 0.422
Activity and expression of Na(+)-H+ exchanger isoforms 1 and 3 in kidney proximal tubules of hypertensive rats.
M P Kelly ... L L Ng
Circ Res 1997 Jun; 80(6)853-60.

Score: 0.422
Role of monocarboxylate transport in the regulation of intracellular pH of renal proximal tubule cells.
W F Boron ... N L Nakhoul
Ciba Found Symp 1988 ; 139()91-105.

Score: 0.421
Regulation of the renal proximal tubule second sodium pump by angiotensins.
C Caruso-Neves ... A G Lopes
Braz J Med Biol Res 2001 Aug; 34(8)1079-84.

Score: 0.421
Defective fluid and HCO(3)(-) absorption in proximal tubule of neuronal nitric oxide synthase-knockout mice.
T Wang ... R G Kalb
Am J Physiol Renal Physiol 2000 Sep; 279(3)F518-24.

Score: 0.420
[The regulation of proximal tubule function]
P J Harris
Fiziol Zh Im I M Sechenova 1994 Jul; 80(7)28-34.

Score: 0.418
Hormonal and osmotic regulation of NaCl transport in renal distal nephron epithelium.
Y Marunaka
Jpn J Physiol 1997 Dec; 47(6)499-511.

Score: 0.418
The renal medullary endothelin system in control of sodium and water excretion and systemic blood pressure.
Donald E Kohan
Curr Opin Nephrol Hypertens 2006 Jan; 15(1)34-40.

Score: 0.417
Angiotensin II stimulation of hydrogen ion secretion in the rat early proximal tubule. Modes of action, mechanism, and kinetics.
F Y Liu ... M G Cogan
J Clin Invest 1988 Aug; 82(2)601-7.

Score: 0.417
Physiologic and pathophysiologic roles of endothelin in the kidney.
A L Clavell ... J C Burnett
Curr Opin Nephrol Hypertens 1994 Jan; 3(1)66-72.

Score: 0.415
[Effect of angiotensin ii on Na+/H+ exchangers of the renal tubule]
J Poggioli ... M Paillard
Nephrologie 1998 ; 19(7)421-5.

Score: 0.415
Mineralocorticoid receptor knockout mice: pathophysiology of Na+ metabolism.
S Berger ... G Schütz
Proc Natl Acad Sci U S A 1998 Aug; 95(16)9424-9.

Score: 0.415
Cell volume regulation in renal cortical cells.
H Völkl ... F Lang
Ren Physiol Biochem 1988 May-Oct; 11(3-5)158-73.

Score: 0.414
Systemic and renal response to salt loading in endothelin-1 knockout mice.
H Morita ... Y Yazaki
J Cardiovasc Pharmacol 1998 ; 31 Suppl 1()S557-60.

Score: 0.414
Renal and intestinal absorptive defects in mice lacking the NHE3 Na+/H+ exchanger.
P J Schultheis ... G E Shull
Nat Genet 1998 Jul; 19(3)282-5.

Score: 0.413
The role of NHERF-1 in the regulation of renal proximal tubule sodium-hydrogen exchanger 3 and sodium-dependent phosphate cotransporter 2a.
Edward J Weinman ... Shirish Shenolikar
J Physiol 2005 Aug; 567(Pt 1)27-32.

Score: 0.411
Nephron function in transgenic mice with selective vascular or tubular expression of Angiotensin-converting enzyme.
Sean P Kessler ... Jurgen Schnermann
J Am Soc Nephrol 2005 Dec; 16(12)3535-42.

Score: 0.411
Chronic regulation of the Na/H antiporter.
R J Alpern ... P A Preisig
J Lab Clin Med 1993 Aug; 122(2)137-40.

Score: 0.411
Aldosterone stimulates surface expression of NHE3 in renal proximal brush borders.
Alexander W Krug ... Michael Gekle
Pflugers Arch 2003 Jul; 446(4)492-6.

Score: 0.409
A gammaGT-AT1A receptor transgene protects renal cortical structure in AT1 receptor-deficient mice.
Thu H Le ... Thomas M Coffman
Physiol Genomics 2004 Aug; 18(3)290-8.

Score: 0.409
Preincubation in acid medium increases Na/H antiporter activity in cultured renal proximal tubule cells.
S Horie ... R J Alpern
Proc Natl Acad Sci U S A 1990 Jun; 87(12)4742-5.

Score: 0.408
Volume regulation is defective in renal proximal tubule cells isolated from KCNE1 knockout mice.
I D Millar ... L Robson
Exp Physiol 2004 Mar; 89(2)173-80.

Score: 0.406
Rat proximal NHE3 adapts to chronic acid-base disorders but not to chronic changes in dietary NaCl intake.
Dominique Eladari ... Régine Chambrey
Am J Physiol Renal Physiol 2002 May; 282(5)F835-43.

Score: 0.405
Regulation of S6 kinase activity in renal proximal tubule.
R C Harris
Am J Physiol 1992 Jul; 263(1 Pt 2)F127-34.

Score: 0.405
Glycosylation of the Na+/H+ exchanger isoform NHE-3 is species specific.
G L Bizal ... M Soleimani
J Lab Clin Med 1996 Sep; 128(3)304-12.

Score: 0.405
Mechanisms of pressure natriuresis: how blood pressure regulates renal sodium transport.
Alicia A McDonough ... Li E Yang
Ann N Y Acad Sci 2003 Apr; 986()669-77.

Score: 0.405
Role of bradykinin in angiotensin-converting enzyme knockout mice.
Hong D Xiao ... Kenneth E Bernstein
Am J Physiol Heart Circ Physiol 2003 Jun; 284(6)H1969-77.

Score: 0.404
Regulation of glomerular filtration and proximal tubule reabsorption.
F G Knox ... G Marchand
Circ Res 1975 Jun; 36(6 Suppl 1)107-18.

Score: 0.404
Renal nerve stimulation augments effect of intraluminal angiotensin II on proximal tubule transport.
Albert Quan ... Michel Baum
Am J Physiol Renal Physiol 2002 Jun; 282(6)F1043-8.

Score: 0.404
The renal proximal tubule renin-angiotensin system.
O W Moe ... W L Henrich
Semin Nephrol 1993 Nov; 13(6)552-7.

Score: 0.403
Differential expression of ileal Na(+)/H(+) exchanger isoforms after enterectomy.
R A Falcone ... B W Warner
J Surg Res 1999 Oct; 86(2)192-7.

Score: 0.403
Volume regulation in renal epithelial cells.
S C Hebert
Semin Nephrol 1987 Mar; 7(1)48-60.

Score: 0.402
The renal nerve is required for regulation of proximal tubule transport by intraluminally produced ANG II.
A Quan ... M Baum
Am J Physiol Renal Physiol 2001 Mar; 280(3)F524-9.

Score: 0.401
Renal and small intestinal sodium-dependent symporters of phosphate and sulphate.
H Murer ... J Biber
J Exp Biol 1994 Nov; 196()167-81.

Score: 0.401
Proximal renal tubular acidosis in TASK2 K+ channel-deficient mice reveals a mechanism for stabilizing bicarbonate transport.
Richard Warth ... Jacques Barhanin
Proc Natl Acad Sci U S A 2004 May; 101(21)8215-20.

Score: 0.401
Na+/H+ antiporters.
T A Krulwich
Biochim Biophys Acta 1983 Dec; 726(4)245-64.

Score: 0.401
Cell volume regulatory mechanisms in progression of renal disease.
S Wärntges ... F Lang
J Nephrol 2001 Sep-Oct; 14(5)319-26.

Score: 0.401
Inhibition of the formation of EETs and 20-HETE with 1-aminobenzotriazole attenuates pressure natriuresis.
Elisabete A Dos Santos ... Richard J Roman
Am J Physiol Regul Integr Comp Physiol 2004 Jul; 287(1)R58-68.

Score: 0.400
Potential role for local luminal angiotensin II in proximal tubule sodium transport.
N Yanagawa
Kidney Int Suppl 1991 Jun; 32()S33-6.

Score: 0.400
Intestinal distribution of human Na+/H+ exchanger isoforms NHE-1, NHE-2, and NHE-3 mRNA.
P K Dudeja ... K Ramaswamy
Am J Physiol 1996 Sep; 271(3 Pt 1)G483-93.

Score: 0.400
Cyclic adenosine monophosphate acutely inhibits and chronically stimulates Na/H antiporter in OKP cells.
A Cano ... R J Alpern
J Clin Invest 1993 Oct; 92(4)1632-8.

Score: 0.399
Antisense inhibition of cyclooxygenase-2 causes a selective suppression of the Na+-H+ exchanger isoform 3 in rat kidney in experimental colitis.
Islam Khan
Nephron 2002 May; 91(1)120-8.

Score: 0.399
Functional and cellular regulation of the myocardial Na+/H+ exchanger.
L Fliegel
J Thromb Thrombolysis 1999 Jul; 8(1)9-14.

Score: 0.399
Renal nervous and spinal pathways and the reflex regulation of extracellular fluid volume.
J W Pearce
Fed Proc 1968 Sep-Oct; 27(5)1142-8.

Score: 0.399
The role of angiotensin II-stimulated renal tubular transport in hypertension.
Kevin D Burns ... Ningjun Li
Curr Hypertens Rep 2003 Apr; 5(2)165-71.

Score: 0.399
Mechanisms and regulation of H+ transport in distal tubule epithelial cells.
G Malnic ... M de M Aires
Wien Klin Wochenschr 1997 Jun; 109(12-13)429-34.

Score: 0.398
Symposium on acid-base homeostasis. The regulation of cerebrospinal fluid pH.
B K Siesjö
Kidney Int 1972 May; 1(5)360-74.

Score: 0.398
Action of glucocorticoids on proximal tubule transport systems.
J L Kinsella
Semin Nephrol 1990 Jul; 10(4)330-8.

Score: 0.398
Towards a molecular view of renal proximal tubular reabsorption of phosphate.
J Biber ... H Murer
Ren Physiol Biochem 1993 Jan-Apr; 16(1-2)37-47.

Score: 0.398
Expression of endothelial nitric oxide synthase is suppressed in the renal vasculature of angiotensinogen-gene knockout mice.
Minoru Kihara ... Satoshi Umemura
Cell Tissue Res 2006 Feb; 323(2)313-20.

Score: 0.397
Role of Sgk1 in salt and potassium homeostasis.
Volker Vallon ... Florian Lang
Am J Physiol Regul Integr Comp Physiol 2005 Jan; 288(1)R4-10.

Score: 0.397
Angiotensin II signal transduction in vascular smooth muscle cells: role of tyrosine kinases.
M Ishida ... B C Berk
Keio J Med 1997 Jun; 46(2)61-8.

Score: 0.397
NaCl restriction upregulates renal Slc26a4 through subcellular redistribution: role in Cl- conservation.
Susan M Wall ... Jill W Verlander
Hypertension 2004 Dec; 44(6)982-7.

Score: 0.397
Tubule function in transgenic mice.
T Wang ... G Giebisch
Exp Nephrol 1998 Sep-Oct; 6(5)447-53.

Score: 0.395
ADH in regulation of blood osmolality and extracellular fluid volume.
B Andersson ... M Rundgren
JPEN J Parenter Enteral Nutr 1980 Mar-Apr; 4(2)88-96.

Score: 0.393
Renal function in the AT1A receptor knockout mouse during normal and volume-expanded conditions.
L Cervenka ... L G Navar
Kidney Int 1999 Nov; 56(5)1855-62.

Score: 0.393
Regulation of sodium balance and blood pressure by the AT(1A) receptor for angiotensin II.
M I Oliverio ... T M Coffman
Hypertension 2000 Feb; 35(2)550-4.

Score: 0.393
Mitogen-activated protein kinase phosphorylation in kidneys of beta(s) sickle cell mice.
M Kiroycheva ... N Bank
J Am Soc Nephrol 2000 Jun; 11(6)1026-32.

Score: 0.392
[Molecular aspects of Na+/H+ exchange in the renal tubule: localization and adaptation to the acid-base state]
P Borensztein ... M Paillard
Nephrologie 1996 ; 17(7)377-81.

Score: 0.392
Recent aspects in the genetic renal mechanisms involved in hypertension.
T Satoh ... M Ishida
Intern Med 1999 Dec; 38(12)919-26.

Score: 0.392
Cytosolic pH regulation in osteoblasts.
J Green
Miner Electrolyte Metab 1994 ; 20(1-2)16-30.

Score: 0.391
Role of angiotensin: insight from gene targeting studies.
S Okubo ... I Ichikawa
Kidney Int Suppl 1997 Dec; 63()S7-9.

Score: 0.391
Bicarbonate transport along the loop of Henle: molecular mechanisms and regulation.
Giovambattista Capasso ... Gerhard Giebisch
J Nephrol 2002 Mar-Apr; 15 Suppl 5()S88-96.

Score: 0.391
Luminal regulation of Na(+)/H(+) exchanger gene expression in rat ileal mucosa.
Marc A Doble ... David I Soybel
J Gastrointest Surg 2002 May-Jun; 6(3)387-95.

Score: 0.391
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Ann N Y Acad Sci 2003 Apr; 986()562-9.

Score: 0.390
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Score: 0.384
Essential role of NHE3 in facilitating formate-dependent NaCl absorption in the proximal tubule.
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Score: 0.384
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Increased blood pressure in transgenic mice expressing both human renin and angiotensinogen in the renal proximal tubule.
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Am J Physiol Renal Physiol 2004 May; 286(5)F965-71.

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J Am Soc Nephrol 2001 Oct; 12(10)2003-11.

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Sodium reabsorption in aldosterone-sensitive distal nephron: news and contributions from genetically engineered animals.
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Curr Opin Nephrol Hypertens 2001 Jan; 10(1)39-47.

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Disorders of the epithelial sodium channel: insights into the regulation of extracellular volume and blood pressure.
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Am J Physiol Regul Integr Comp Physiol 2005 Mar; 288(3)R685-91.

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Am J Physiol 1998 Jul; 275(1 Pt 2)F74-8.

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A novel model of polyhydramnios: amniotic fluid volume is increased in aquaporin 1 knockout mice.
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Molecular cloning, functional expression, tissue distribution, and in situ hybridization of the renal sodium phosphate (Na+/P(i)) transporter in the control and hypophosphatemic mouse.
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Glucocorticoid stimulation of ileal Na+ absorptive cell brush border Na+/H+ exchange and association with an increase in message for NHE-3, an epithelial Na+/H+ exchanger isoform.
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Hypervitaminosis D mediates compensatory Ca2+ hyperabsorption in TRPV5 knockout mice.
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Immunological detection of Na(+)/H(+) exchangers in the gills of a hagfish, Myxine glutinosa, an elasmobranch, Raja erinacea, and a teleost, Fundulus heteroclitus.
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[Vasoactive peptides and the development of renal sclerosis: contribution of transgenes]
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NHERF: targeting and trafficking membrane proteins.
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Modification of the internal pH sensitivity of the Na+/H+ antiporter by parathyroid hormone in a cultured renal cell line.
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Prevention of acute ischemic renal failure by targeted delivery of growth factors to the proximal tubule in transgenic mice: the efficacy of parathyroid hormone-related protein and hepatocyte growth factor.
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