FRISC: The Faculty Research Interests Science Comparator

Richard Auchus, Ph.D., M.D.
Assistant Professor of Internal Medicine, Division of Endocrinology and
Metabolism
Biological
Chemistry
Molecular Biophysics
Office: 214-648-6751
FAX: 214-648-8917
Email: richard.auchus@utsouthwestern.edu
Homepage: http://www.swmed.edu/home_pages/endocrine/auchusindex.htm

New This Month | New This Year | Abstract | Selected Publications | FRISC Statistics Results - FULL MEDLINE:

Chimerogenesis in estimation of specificity and pathway directions for cytochrome p45017alpha catalyzed reactions.
A A Gilep ... S A Usanov
Biochemistry (Mosc) 2004 Apr; 69(4)364-75.
Score: 0.484
Cytochrome b5 augments the 17,20-lyase activity of human P450c17 without direct electron transfer.
R J Auchus ... W L Miller
J Biol Chem 1998 Feb; 273(6)3158-65.
Score: 0.460
Xenopus laevis CYP17 regulates androgen biosynthesis independent of the cofactor cytochrome b5.
Wei-Hsiung Yang ... Stephen R Hammes
J Biol Chem 2005 Mar; 280(11)10196-201.
Score: 0.455
Genetic diseases of steroid metabolism.
P C White
Vitam Horm 1994 ; 49()131-95.
Score: 0.439
[The regulation of steroidogenesis by 17 alpha-hydroxylase/17,20-lyase (P450c17)]
M Katagiri ... N Kagawa
Nippon Yakurigaku Zasshi 1998 Jul; 112(1)43-50.
Score: 0.436
The human steroid hydroxylases CYP1B1 and CYP11B2.
Matthias Bureik ... Rita Bernhardt
Biol Chem 2002 Oct; 383(10)1537-51.
Score: 0.434
Assessment of porcine and human 16-ene-synthase, a third activity of P450c17, in the formation of an androstenol precursor. Role of recombinant cytochrome b5 and P450 reductase.
Penny Soucy ... Van Luu-The
Eur J Biochem 2003 Mar; 270(6)1349-55.
Score: 0.429
The genetic and functional basis of isolated 17,20-lyase deficiency.
D H Geller ... W L Miller
Nat Genet 1997 Oct; 17(2)201-5.
Score: 0.403
Towards a unifying mechanism for CYP17 mutations that cause isolated 17,20-lyase deficiency.
Richard J Auchus ... Manisha K Gupta
Endocr Res 2002 Nov; 28(4)443-7.
Score: 0.400
The enantiomer of progesterone (ent-progesterone) is a competitive inhibitor of human cytochromes P450c17 and P450c21.
Richard J Auchus ... Douglas F Covey
Arch Biochem Biophys 2003 Jan; 409(1)134-44.
Score: 0.399
Effects of C19 steroids on adrenal steroidogenic enzyme activities and their mRNA levels in guinea-pig fasciculata-glomerulosa cells in primary culture.
P H Provencher ... A Bélanger
J Endocrinol 1992 Feb; 132(2)269-76.
Score: 0.394
Molecular modeling of human P450c17 (17alpha-hydroxylase/17,20-lyase): insights into reaction mechanisms and effects of mutations.
R J Auchus ... W L Miller
Mol Endocrinol 1999 Jul; 13(7)1169-82.
Score: 0.393
Effect of ACTH on steroidogenic enzymes in guinea pig fasciculata-glomerulosa cells: changes in activity and mRNA levels.
P H Provencher ... A Belanger
J Steroid Biochem Mol Biol 1992 Jan; 41(1)59-67.
Score: 0.388
Effect of leptin on CYP17 enzymatic activities in human adrenal cells: new insight in the onset of adrenarche.
A Biason-Lauber ... E J Schoenle
Endocrinology 2000 Apr; 141(4)1446-54.
Score: 0.379
Molecular cloning and expression of guinea pig cytochrome P450c17 cDNA (steroid 17 alpha-hydroxylase/17,20 lyase): tissue distribution, regulation, and substrate specificity of the expressed enzyme.
Y Tremblay ... A Bélanger
DNA Cell Biol 1994 Dec; 13(12)1199-212.
Score: 0.376
Genomics of steroid hormones: in silico analysis of nucleotide sequence variants (polymorphisms) of the enzymes involved in the biosynthesis and metabolism of steroid hormones.
Peter Igaz ... Károly Rácz
J Steroid Biochem Mol Biol 2002 Nov; 82(4-5)359-67.
Score: 0.372
Differential inhibition of 17alpha-hydroxylase and 17,20-lyase activities by three novel missense CYP17 mutations identified in patients with P450c17 deficiency.
Erica L T Van Den Akker ... Frank H De Jong
J Clin Endocrinol Metab 2002 Dec; 87(12)5714-21.
Score: 0.369
Pitfalls in characterizing P450c17 mutations associated with isolated 17,20-lyase deficiency.
M K Gupta ... R J Auchus
J Clin Endocrinol Metab 2001 Sep; 86(9)4416-23.
Score: 0.369
The 17, 20-lyase activity of cytochrome p450c17 from human fetal testis favors the delta5 steroidogenic pathway.
Christa E Flück ... Richard J Auchus
J Clin Endocrinol Metab 2003 Aug; 88(8)3762-6.
Score: 0.364
CYP17 mutation E305G causes isolated 17,20-lyase deficiency by selectively altering substrate binding.
Daniel P Sherbet ... Richard J Auchus
J Biol Chem 2003 Dec; 278(49)48563-9.
Score: 0.362
Physiological and pathological effects of steroids on the function of the adrenal cortex.
P J Hornsby
J Steroid Biochem 1987 ; 27(4-6)1161-71.
Score: 0.362
Subcellular targeting analysis of SDR-type hydroxysteroid dehydrogenases.
C Filling ... U C Oppermann
Mol Cell Endocrinol 2001 Jan; 171(1-2)99-101.
Score: 0.361
Clinical inquiries. Should liver enzymes be checked in a patient taking niacin?
Gloria S Rizakallah ... Louis Sanner
J Fam Pract 2005 Mar; 54(3)265-8.
Score: 0.361
The use of computational chemistry in the study of sex steroid biosynthesis.
R J Auchus
Endocr Res 1998 Aug-Nov; 24(3-4)541-7.
Score: 0.360
Purification of multiple forms of the soluble 17alpha-hydroxy steroid dehydrogenase or rabbit liver.
S Hasnain ... D G Williamson
Biochem J 1975 Jun; 147(3)457-61.
Score: 0.360
Serum activity of lysosomal enzymes in relationship to contraceptive steroid dose.
M H Briggs ... M Briggs
Curr Med Res Opin 1975 ; 3(4)203-5.
Score: 0.359
Subcellular distribution of delta 5-3 beta-hydroxy steroid dehydrogenase in the granulosa cells of the domestic fowl (Gallus domesticus).
D G Armstrong
Biochem J 1979 Sep; 181(3)685-9.
Score: 0.358
[Proteolytic enzymes: subcellular localization, properties and participation in neuropeptide metabolism]
A N Vernigora ... M T Gengin
Biokhimiia 1996 May; 61(5)771-85.
Score: 0.358
A 17 beta-hydroxysteroid dehydrogenase of female rabbit liver cytosol. Purification and characterization of multiple forms of the enzyme.
G R Antoun ... D G Williamson
Biochem J 1985 Jan; 225(2)383-90.
Score: 0.357
Regulation of steroid-transforming enzymes by endogenous steroids.
D B Gower ... G M Cooke
J Steroid Biochem 1983 Oct; 19(4)1527-56.
Score: 0.356
5alpha-reduced C21 steroids are substrates for human cytochrome P450c17.
Manisha K Gupta ... Richard J Auchus
Arch Biochem Biophys 2003 Oct; 418(2)151-60.
Score: 0.356
Cytochrome P450 17alpha hydroxylase/17,20 lyase (CYP17) function in cholesterol biosynthesis: identification of squalene monooxygenase (epoxidase) activity associated with CYP17 in Leydig cells.
Ying Liu ... Vassilios Papadopoulos
Mol Endocrinol 2005 Jul; 19(7)1918-31.
Score: 0.356
Effect of chronic ACTH treatment on guinea-pig adrenal steroidogenesis: steroid plasma levels, steroid adrenal levels, activity of steroidogenic enzymes and their steady-state mRNA levels.
P H Provencher ... A Belanger
J Steroid Biochem Mol Biol 1992 Jan; 41(1)69-78.
Score: 0.356
Expression of bovine 17 alpha-hydroxylase cytochrome P-450 cDNA in nonsteroidogenic (COS 1) cells.
M X Zuber ... M R Waterman
Science 1986 Dec; 234(4781)1258-61.
Score: 0.356
P450c17 mutations R347H and R358Q selectively disrupt 17,20-lyase activity by disrupting interactions with P450 oxidoreductase and cytochrome b5.
D H Geller ... W L Miller
Mol Endocrinol 1999 Jan; 13(1)167-75.
Score: 0.355
Mechanism based inhibition of hydroxysteroid dehydrogenases.
T M Penning ... J W Ricigliano
J Enzyme Inhib 1991 ; 5(3)165-98.
Score: 0.355
Isolation of multiple forms of indanol dehydrogenase associated with 17 beta-hydroxysteroid dehydrogenase activity from male rabbit liver.
A Hara ... H Sawada
Arch Biochem Biophys 1986 Aug; 249(1)225-36.
Score: 0.354
The hypophysis in the regulation of androgen and oestrogen dependent enzyme activities of steroid hormone metabolism in rat liver cytosol.
R Ghraf ... H Schriefers
Hoppe Seylers Z Physiol Chem 1975 Feb; 356(2)127-34.
Score: 0.354
Radiation effects on rat testes. IX. Studies on oxidative enzymes after partial body gamma irradiation.
G S Gupta ... S R Bawa
Strahlentherapie 1975 Aug; 150(2)158-61.
Score: 0.354
Steroid 17,20-lyase from testis microsomes: participation of NADPH cytochrome c reductase.
G Betz ... P Tsai
Arch Biochem Biophys 1974 Jul; 163(1)318-23.
Score: 0.353
The function and roles of P450c17 in androgen excess states.
R J Auchus ... K M Worthy
J Pediatr Endocrinol Metab 2000 ; 13 Suppl 5()1271-5.
Score: 0.352
17alpha-hydroxylase/17,20-lyase deficiency caused by a novel homozygous mutation (Y27Stop) in the cytochrome CYP17 gene.
Karsten Müssig ... Baptist Gallwitz
J Clin Endocrinol Metab 2005 Jul; 90(7)4362-5.
Score: 0.351
Modeling study of some inhibitors of 17,20-lyase, a component of the enzyme 17 alpha-hydroxylase/17,20-lyase: a novel approach.
S Ahmed ... J Keane
Biochem Biophys Res Commun 1998 Dec; 253(2)273-6.
Score: 0.350
The in vitro and in vivo effect of estradiol upon the 17 alpha-hydroxylase and C17,20-lyase activity in the ovaries of immature hypophysectomized rats.
D C Johnson ... C H Tsai-Morris
Mol Cell Endocrinol 1984 May; 35(2-3)199-204.
Score: 0.350
Combined 17alpha-Hydroxylase/17,20-lyase deficiency caused by Phe93Cys mutation in the CYP17 gene.
Alfredo Di Cerbo ... Anna Savoia
J Clin Endocrinol Metab 2002 Feb; 87(2)898-905.
Score: 0.349
Cellular and subcellular compartmentalization of steroid metabolism in the rat testis.
H J Van Der Molen ... F H De Jong
J Reprod Fertil 1975 Aug; 44(2)351-62.
Score: 0.347
Co-evolution of steroidogenic and steroid-inactivating enzymes and adrenal and sex steroid receptors.
Michael E Baker
Mol Cell Endocrinol 2004 Feb; 215(1-2)55-62.
Score: 0.346
The effect of cytochrome b5 on progesterone metabolism in the ovine adrenal.
P Swart ... C Dreesbeimdieke
Endocr Res 1995 Feb-May; 21(1-2)297-306.
Score: 0.346
Steroidogenesis in human adrenocortical carcinoma: biochemical activities, immunohistochemistry, and in situ hybridization of steroidogenic enzymes and histopathologic study in nine cases.
H Sasano ... T Nishikawa
Hum Pathol 1993 Apr; 24(4)397-404.
Score: 0.345
Heterogeneity of cytochrome P-450 in rat testis microsomes.
G Betz ... R Weakley
J Biol Chem 1976 May; 251(9)2839-41.
Score: 0.344
Biotransformation of steroids by the fission yeast Schizosaccharomyces pombe.
T Pajic ... R Komel
Yeast 1999 Jun; 15(8)639-45.
Score: 0.343
Steroid transformation enzymes as critical regulators of steroid action in vivo.
W C Song ... M H Melner
Endocrinology 2000 May; 141(5)1587-9.
Score: 0.341
Properties of the multiple forms of the soluble 17alpha-hydroxy steroid dehydrogenase of rabbit liver.
S Hasnain ... D G Williamson
Biochem J 1977 Feb; 161(2)279-83.
Score: 0.340
Ovine steroid 17alpha-hydroxylase cytochrome P450: characteristics of the hydroxylase and lyase activities of the adrenal cortex enzyme.
Pieter Swart ... J Ian Mason
Arch Biochem Biophys 2003 Jan; 409(1)145-52.
Score: 0.339
Structural characterization of normal and mutant human steroid 17 alpha-hydroxylase genes: molecular basis of one example of combined 17 alpha-hydroxylase/17,20 lyase deficiency.
M Kagimoto ... M R Waterman
Mol Endocrinol 1988 Jun; 2(6)564-70.
Score: 0.338
Seasonal changes in testicular steroidogenesis in the toad Bufo arenarum H.
L F Canosa ... N R Ceballos
Gen Comp Endocrinol 2002 Feb; 125(3)426-34.
Score: 0.338
Effect of chronic ethanol feeding on testicular content of enzymes required for testosteronogenesis.
Y B Chiao ... D H Van Thiel
Alcohol Clin Exp Res 1981 ; 5(2)230-6.
Score: 0.337
Steroid 17 alpha-hydroxylase and 17,20-lyase activities of P450c17: contributions of serine106 and P450 reductase.
D Lin ... W L Miller
Endocrinology 1993 Jun; 132(6)2498-506.
Score: 0.336
Steroid metabolism in the mammalian brain: 5alpha-reduction and aromatization.
F Celotti ... A Poletti
Brain Res Bull 1997 ; 44(4)365-75.
Score: 0.335
Influence of steroid distribution between microsomes and soluble fraction on steroid metabolism by microsomal enzymes.
K Matsumoto ... L T Samuels
Endocrinology 1969 Sep; 85(3)402-9.
Score: 0.335
Immunoelectron microscopic localization of 3beta-hydroxysteroid dehydrogenase and type 5 17beta-hydroxysteroid dehydrogenase in the human prostate and mammary gland.
G Pelletier ... F Labrie
J Mol Endocrinol 2001 Feb; 26(1)11-9.
Score: 0.334
What's new in the localization of sex steroids in the human ovary and its tumors?
H Sasano ... N Sasano
Pathol Res Pract 1989 Dec; 185(6)942-8.
Score: 0.334
[pH-dependence of hormone-binding and enzymatic activity of estrophilic hydroxysteroid dehydrogenase from the rabbit liver]
A N Smirnov
Biokhimiia 1990 Jun; 55(6)1073-80.
Score: 0.334
Minireview: cellular redox state regulates hydroxysteroid dehydrogenase activity and intracellular hormone potency.
Anil K Agarwal ... Richard J Auchus
Endocrinology 2005 Jun; 146(6)2531-8.
Score: 0.332
Steroid hormone biotransformation and xenobiotic induction of hepatic steroid metabolizing enzymes.
Li You
Chem Biol Interact 2004 Apr; 147(3)233-46.
Score: 0.332
Studies on enzyme reactions related to steroid biosynthesis. 3. Distribution of the testicular enzymes related to androgen production between the seminiferous tubules and interstitial tissue.
H Inano
J Steroid Biochem 1974 Apr; 5(2)145-9.
Score: 0.332
ENZYMES and their activities.
Br Med J 1953 Oct; 2(4842)927-8.
Score: 0.331
Sex steroid metabolism in the tibial growth plate of the rat.
B C J Van Der Eerden ... M Karperien
Endocrinology 2002 Oct; 143(10)4048-55.
Score: 0.330
[Biosynthesis of steroids in the adrenal gland]
V Plavsić
Lijec Vjesn 1996 Mar; 118 Suppl 1()9-10.
Score: 0.329
Characterization and modulation of sex steroid metabolizing activity in normal human keratinocytes in primary culture and HaCaT cells.
Sébastien Gingras ... Jacques Simard
J Steroid Biochem Mol Biol 2003 Nov; 87(2-3)167-79.
Score: 0.329
Biochemical markers of aging.
E R Stadtman
Exp Gerontol 1988 ; 23(4-5)327-47.
Score: 0.328
Steroid 17,20-lyase: the effect of detergents on enzymic activity and microsomal composition.
G Betz ... D Michels
Steroids 1973 Jun; 21(6)785-800.
Score: 0.328
Where is the glycolytic complex? A critical evaluation of present data from muscle tissue.
S P Brooks ... K B Storey
FEBS Lett 1991 Jan; 278(2)135-8.
Score: 0.327
A complex heterozygous mutation of His373Leu and Asp487-Ser488-Phe489 deletion in human cytochrome P450c17 causes 17alpha-hydroxylase/17,20-lyase deficiency in three Chinese sisters.
Jie Qiao ... Jia-Lun Chen
Mol Cell Endocrinol 2003 Mar; 201(1-2)189-95.
Score: 0.327
Identification of 7(8) and 8(9) unsaturated adrenal steroid metabolites produced by patients with 7-dehydrosterol-delta7-reductase deficiency (Smith-Lemli-Opitz syndrome).
Cedric Shackleton ... Forbes D Porter
J Steroid Biochem Mol Biol 2002 Oct; 82(2-3)225-32.
Score: 0.327
The role of the hypophysis in the regulation of sex differences in the activities of enzymes involved in hepatic steroid hormone metabolism.
E R Lax ... H Schriefers
Hoppe Seylers Z Physiol Chem 1974 Oct; 355(10)1325-31.
Score: 0.326
GONADOTROPIN REGULATION OF THE ACTIVITIES OF DEHYDROGENASE ENZYMES OF THE OVARY.
K W MCKERNS
Biochim Biophys Acta 1965 Mar; 97()542-50.
Score: 0.326
Dual regulation of 21-hydroxylase activity by sex steroid hormones in rat hepatocytes.
A Endoh ... Y Igarashi
J Steroid Biochem Mol Biol 1995 Aug; 54(3-4)163-5.
Score: 0.326
Human cytochrome b5 requires residues E48 and E49 to stimulate the 17,20-lyase activity of cytochrome P450c17.
Jacqueline L Naffin-Olivos ... Richard J Auchus
Biochemistry 2006 Jan; 45(3)755-62.
Score: 0.326
Immunoelectron microscopic localization of three key steroidogenic enzymes (cytochrome P450(scc), 3 beta-hydroxysteroid dehydrogenase and cytochrome P450(c17)) in rat adrenal cortex and gonads.
G Pelletier ... F Labrie
J Endocrinol 2001 Nov; 171(2)373-83.
Score: 0.326
Steroidogenesis in rat leydig cells: changes in activity of 5-ane and 5-ene 3beta-hydroxysteroid dehydrogenases during sexual maturation.
J P Wiebe
Endocrinology 1976 Feb; 98(2)505-13.
Score: 0.326
17 alpha-Hydroxylase/17,20-lyase defects.
T Yanase
J Steroid Biochem Mol Biol 1995 Jun; 53(1-6)153-7.
Score: 0.325
Mutation R96W in cytochrome P450c17 gene causes combined 17 alpha-hydroxylase/17-20-lyase deficiency in two French Canadian patients.
N Laflamme ... J Simard
J Clin Endocrinol Metab 1996 Jan; 81(1)264-8.
Score: 0.325
Steroidogenic enzyme expression in the rat cochlea.
Eric Lecain ... Patrice Tran Ba Huy
Acta Otolaryngol 2003 Jan; 123(2)187-91.
Score: 0.324
17alpha-hydroxylase/17,20-lyase deficiency as a model to study enzymatic activity regulation: role of phosphorylation.
A Biason-Lauber ... M Zachmann
J Clin Endocrinol Metab 2000 Mar; 85(3)1226-31.
Score: 0.323
Identification of a single nucleotide polymorphism in porcine testis cytochrome P450-c17 (CYP17) and its effect on steroidogenesis.
Zhihong Lin ... E James Squires
Biochem Genet 2005 Oct; 43(9-10)531-42.
Score: 0.323
3-Hydroxy steroid dehydrogenase activities of cortisone reductase.
W Gibb ... J Jeffery
Biochem J 1973 Dec; 135(4)881-8.
Score: 0.322
Synthesis and trafficking of alkaloid biosynthetic enzymes.
Peter J Facchini ... Benoit St-Pierre
Curr Opin Plant Biol 2005 Dec; 8(6)657-66.
Score: 0.322
Danazol inhibition of steroidogenesis in the human corpus luteum.
R L Barbieri ... K J Ryan
Obstet Gynecol 1981 Jun; 57(6)722-4.
Score: 0.322
Quantitative assessment of endogenous testicular and adrenal sex steroids and of steroid metabolizing enzymes in untreated human prostatic cancerous tissue.
H Klein ... K D Voigt
J Steroid Biochem 1988 ; 30(1-6)119-30.
Score: 0.321
Differential estrogen substrate specificities for transiently expressed human placental 17 beta-hydroxysteroid dehydrogenase and an endogenous enzyme expressed in cultured COS-m6 cells.
M Poutanen ... R Vihko
Endocrinology 1993 Dec; 133(6)2639-44.
Score: 0.321
Hepatic, testicular aldehyde dehydrogenase and sex steroids.
F S Messiha
Proc West Pharmacol Soc 1988 ; 31()75-6.
Score: 0.321
Activities of 21-hydroxylase, 17alpha-hydroxylase and 17,20-lyase.
B Ambrosi ... R Libé
Eur J Endocrinol 2000 Apr; 142(4)411-2.
Score: 0.321
[Cellular and subcellular distribution of enzymes involved in steroid biosynthesis (author's transl)]
B Szukalski
Postepy Biochem 1977 ; 23(1)95-111.
Score: 0.320
Serine phosphorylation of human P450c17 increases 17,20-lyase activity: implications for adrenarche and the polycystic ovary syndrome.
L H Zhang ... W L Miller
Proc Natl Acad Sci U S A 1995 Nov; 92(23)10619-23.
Score: 0.320
Multiplicity of mammalian reductases for xenobiotic carbonyl compounds.
Toshiyuki Matsunaga ... Akira Hara
Drug Metab Pharmacokinet 2006 Feb; 21(1)1-18.
Score: 0.318
Proceedings: The role of the hypophysis in the regulation of sex differences in the activities of enzymes involved in hepatic steroid hormone metabolism.
E R Lax ... H Schriefers
Hoppe Seylers Z Physiol Chem 1974 Oct; 355(10)1223.
Score: 0.318
Molecular cloning and heterologous expression in E. coli of cytochrome P45017alpha. Comparison of structural and functional properties of substrate-specific cytochromes P450 from different species.
A A Gilep ... S A Usanov
Biochemistry (Mosc) 2003 Jan; 68(1)86-98.
Score: 0.317
Structure of genes encoding steroidogenic enzymes.
W L Miller
J Steroid Biochem 1987 ; 27(4-6)759-66.
Score: 0.317
A novel compound heterozygous mutation in the CYP17 (P450 17alpha-hydroxylase) gene leading to 17alpha-hydroxylase/17,20-lyase deficiency.
Jong Ryeal Hahm ... Moon-Kyu Lee
Metabolism 2003 Apr; 52(4)488-92.
Score: 0.317
[Cellular biology of sex steroid and clinical implication]
T Tamaya
Nippon Naibunpi Gakkai Zasshi 1993 Oct; 69(9)963-72.
Score: 0.317
Role of enzymes and tissue-specific actions of steroids.
M J Reed
Maturitas 2004 Aug; 48 Suppl 1()S18-23.
Score: 0.317
Reconstitution of steroid 17,20-lyase activity after separation and purification of cytochrome P-450 and its reductase from rat testis microsomes.
G Betz ... D Hales
Endocrinology 1980 Oct; 107(4)1055-60.
Score: 0.316
Overview of steroidogenic enzymes in the pathway from cholesterol to active steroid hormones.
Anita H Payne ... Dale B Hales
Endocr Rev 2004 Dec; 25(6)947-70.
Score: 0.316
Rat liver 3 alpha-hydroxysteroid dehydrogenase.
T M Penning ... R B Sharp
Steroids 1986 Apr-May; 47(4-5)221-47.
Score: 0.316
Androgen synthesis in a songbird: a study of cyp17 (17alpha-hydroxylase/C17,20-lyase) activity in the zebra finch.
B A Schlinger ... L Thompson
Gen Comp Endocrinol 1999 Jan; 113(1)46-58.
Score: 0.315
Use of enzyme activities as indices of maximum rates of fuel utilization.
E A Newsholme ... V A Zammit
Ciba Found Symp 1979 ; (73)245-58.
Score: 0.314
Testicular enzymes related to steroid metabolism.
B i Tamaoki ... K Suzuki
Curr Top Mol Endocrinol 1975 ; 2()123-32.
Score: 0.314
Failed to fetch article title! Article may not be available.
Score: 0.314
Xenopus laevis ovarian CYP17 is a highly potent enzyme expressed exclusively in oocytes. Evidence that oocytes play a critical role in Xenopus ovarian androgen production.
Wei-Hsiung Yang ... Stephen R Hammes
J Biol Chem 2003 Mar; 278(11)9552-9.
Score: 0.313
Regulation of 21-hydroxylase activity by steroids.
A Bélanger ... S Perron
Endocr Res 1995 Feb-May; 21(1-2)329-41.
Score: 0.313
Diagnosis and management of congenital adrenal hyperplasia.
M I New
Annu Rev Med 1998 ; 49()311-28.
Score: 0.312
3alpha-, 7alpha- and 12alpha-hydroxysteroid dehydrogenase activities from Clostridium perfringens.
I A Macdonald ... G A Costain
Biochim Biophys Acta 1976 Nov; 450(2)142-53.
Score: 0.311
Human 17beta-hydroxysteroid dehydrogenases types 1, 2, and 3 catalyze bi-directional equilibrium reactions, rather than unidirectional metabolism, in HEK-293 cells.
Naveed Khan ... Richard J Auchus
Arch Biochem Biophys 2004 Sep; 429(1)50-9.
Score: 0.311
Enzymes of glucose catabolism in hydra. I. Relative activities of enzymes and absence of 6-phosphogluconate dehydrogenase.
C L Rutherford ... H M Lenhoff
Arch Biochem Biophys 1969 Aug; 133(1)119-27.
Score: 0.311
Sex steroids and memory.
Ciba Found Symp 1995 ; 191()113-21.
Score: 0.309
Structural basis for flip-flop action of thiamin pyrophosphate-dependent enzymes revealed by human pyruvate dehydrogenase.
Ewa M Ciszak ... Mulchand S Patel
J Biol Chem 2003 Jun; 278(23)21240-6.
Score: 0.308
[The effect of cofactors on the binding of steroid substrates with extrophilic hydroxysteroid dehydrogenase in the rabbit liver]
A N Smirnov
Biull Eksp Biol Med 1990 Mar; 109(3)250-2.
Score: 0.308
Endocrine end-points in rheumatoid arthritis.
L Castagnetta ... G Carruba
Ann N Y Acad Sci 1999 Jun; 876()180-91; discussion 191-2.
Score: 0.308
Inhibition of glucose-6-phosphate dehydrogenase by synthetic steroids and steroid conjugates.
G W Oertel ... P Benes
Acta Endocrinol Suppl (Copenh) 1973 ; 173()114.
Score: 0.308
Subcellular localization of cytochrome P450, and activities of several enzymes responsible for drug metabolism in the human brain.
J F Ghersi-Egea ... A Minn
Biochem Pharmacol 1993 Feb; 45(3)647-58.
Score: 0.308
Sex steroids regulate intermediary metabolism in Oreochromis mossambicus.
Francis Sunny ... Oommen V Oommen
Endocr Res 2002 Aug; 28(3)175-88.
Score: 0.308
Modulation of 17alpha-hydroxylase/17,20-lyase activity of guinea pig cytochrome P450c17 by site-directed mutagenesis.
C Beaudoin ... A Bélanger
DNA Cell Biol 1998 Aug; 17(8)707-15.
Score: 0.308
THE STEROIDS 4. STEROID PREPARATIONS.
C A BIRCH
Nurs Times 1965 Apr; 61()525.
Score: 0.307
Assessment of the ability of type 2 cytochrome b5 to modulate 17,20-lyase activity of human P450c17.
Penny Soucy ... Van Luu-The
J Steroid Biochem Mol Biol 2002 Jan; 80(1)71-5.
Score: 0.307
Overview of dehydroepiandrosterone biosynthesis.
Richard J Auchus
Semin Reprod Med 2004 Nov; 22(4)281-8.
Score: 0.307
Characterization of UDP-glucuronosyltransferases active on steroid hormones.
D W Hum ... S Dubois
J Steroid Biochem Mol Biol 1999 Apr-Jun; 69(1-6)413-23.
Score: 0.307
Combined 17 alpha-hydroxylase/17,20-lyase deficiency due to a 7-basepair duplication in the N-terminal region of the cytochrome P45017 alpha (CYP17) gene.
T Yanase ... M R Waterman
J Clin Endocrinol Metab 1990 May; 70(5)1325-9.
Score: 0.306
Hydroxysteroid dehydrogenase activity associated with sexual differentiation in embryos of the turtle Trachemys scripta.
E O Thomas ... D Crews
Biol Reprod 1992 Jan; 46(1)140-5.
Score: 0.306
Changes in erythrocyte enzyme activities during erythrocyte aging in alcoholism.
E Mezey ... D L Rhodes
Alcohol Clin Exp Res 1988 Jun; 12(3)422-6.
Score: 0.306
Activities of enzymes responsible for steroid biosynthesis and cholesterol ester metabolism in rabbit ovarian interstitial tissue and corpora lutea. A comparison of enzyme activities with flow rates.
A P Flint ... D T Armstrong
Biochem J 1973 Feb; 132(2)301-11.
Score: 0.306
Biotransformations of steroids.
L Sedlaczek
Crit Rev Biotechnol 1988 ; 7(3)187-236.
Score: 0.306
Human cytochrome P-450 enzymes.
F P Guengerich
Life Sci 1992 ; 50(20)1471-8.
Score: 0.306
Enzymes of triacylglycerol synthesis and their regulation.
Rosalind A Coleman ... Douglas P Lee
Prog Lipid Res 2004 Mar; 43(2)134-76.
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