FRISC: The Faculty Research Interests Science Comparator

Preet Chaudhary, M.D., Ph.D.
Assistant Professor of Internal Medicine
Cell
Regulation
Office: 214-648-1837
FAX: 214-648-4940
Email: preet.chaudhary@utsouthwestern.edu

New This Month | New This Year | Abstract | Selected Publications | FRISC Statistics Results - FULL MEDLINE:

TRAIL-R2: a novel apoptosis-mediating receptor for TRAIL.
H Walczak ... C T Rauch
EMBO J 1997 Sep; 16(17)5386-97.

Score: 0.558
TAJ, a novel member of the tumor necrosis factor receptor family, activates the c-Jun N-terminal kinase pathway and mediates caspase-independent cell death.
M T Eby ... P M Chaudhary
J Biol Chem 2000 May; 275(20)15336-42.

Score: 0.530
Regulatory roles and molecular signaling of TNF family members in osteoclasts.
Xu Feng
Gene 2005 Apr; 350(1)1-13.

Score: 0.522
Death receptor 5, a new member of the TNFR family, and DR4 induce FADD-dependent apoptosis and activate the NF-kappaB pathway.
P M Chaudhary ... L Hood
Immunity 1997 Dec; 7(6)821-30.

Score: 0.519
Modulation of life and death by the TNF receptor superfamily.
S J Baker ... E P Reddy
Oncogene 1998 Dec; 17(25)3261-70.

Score: 0.515
Activation of the NF-kappaB pathway by caspase 8 and its homologs.
P M Chaudhary ... L Hood
Oncogene 2000 Sep; 19(39)4451-60.

Score: 0.508
TRAIL receptors 1 (DR4) and 2 (DR5) signal FADD-dependent apoptosis and activate NF-kappaB.
P Schneider ... J Tschopp
Immunity 1997 Dec; 7(6)831-6.

Score: 0.498
The signaling adaptors and pathways activated by TNF superfamily.
Paul W Dempsey ... Genhong Cheng
Cytokine Growth Factor Rev 2003 Jun-Aug; 14(3-4)193-209.

Score: 0.495
TNF receptor (TNFR)-associated factor (TRAF) 3 serves as an inhibitor of TRAF2/5-mediated activation of the noncanonical NF-kappaB pathway by TRAF-binding TNFRs.
Julia Hauer ... Hartmut Engelmann
Proc Natl Acad Sci U S A 2005 Feb; 102(8)2874-9.

Score: 0.495
Tumor necrosis factor receptor-associated factor (TRAF) 2 and its role in TNF signaling.
H Wajant ... P Scheurich
Int J Biochem Cell Biol 2001 Jan; 33(1)19-32.

Score: 0.484
TRAIL-induced signalling and apoptosis.
Marion MacFarlane
Toxicol Lett 2003 Apr; 139(2-3)89-97.

Score: 0.481
Tumor necrosis factor receptor (TNFR)-associated factor 5 is a critical intermediate of costimulatory signaling pathways triggered by glucocorticoid-induced TNFR in T cells.
Edward M Esparza ... Robert H Arch
J Biol Chem 2006 Mar; 281(13)8559-64.

Score: 0.458
Molecular piracy of Kaposi's sarcoma associated herpesvirus.
J Choi ... J U Jung
Cytokine Growth Factor Rev 2001 Jun-Sep; 12(2-3)245-57.

Score: 0.457
[TNF-related apoptosis-inducing ligand signaling pathway and hematopoietic malignancies]
Jun Qian ... Zi-Xing Chen
Zhongguo Shi Yan Xue Ye Xue Za Zhi 2002 Oct; 10(5)472-7.

Score: 0.456
Activation of the c-Jun N-terminal kinase/stress-activated protein kinase pathway by overexpression of caspase-8 and its homologs.
P M Chaudhary ... L Hood
J Biol Chem 1999 Jul; 274(27)19211-9.

Score: 0.453
Cytotoxic signal transduction pathways via TNF family receptors.
I P Beletsky ... O V Proussakova
Biochemistry (Mosc) 2002 Mar; 67(3)312-28.

Score: 0.453
On the TRAIL to apoptosis.
Tudor M Baetu ... John Hiscott
Cytokine Growth Factor Rev 2002 Jun; 13(3)199-207.

Score: 0.452
Pathways leading to cell death in T cells.
B Wong ... Y Choi
Curr Opin Immunol 1997 Jun; 9(3)358-64.

Score: 0.452
Identification and molecular cloning of two novel receptors for the cytotoxic ligand TRAIL.
M MacFarlane ... E S Alnemri
J Biol Chem 1997 Oct; 272(41)25417-20.

Score: 0.450
Modulation of cell signaling pathways by Kaposi's sarcoma-associated herpesvirus (KSHVHHV-8).
Blossom Damania
Cell Biochem Biophys 2004 ; 40(3)305-22.

Score: 0.448
Shared pathways: death receptors and cytotoxic drugs in cancer therapy.
I Peták ... J A Houghton
Pathol Oncol Res 2001 ; 7(2)95-106.

Score: 0.446
The ectodermal dysplasia receptor activates the nuclear factor-kappaB, JNK, and cell death pathways and binds to ectodysplasin A.
A Kumar ... P M Chaudhary
J Biol Chem 2001 Jan; 276(4)2668-77.

Score: 0.446
The K1 protein of Kaposi's sarcoma-associated herpesvirus activates the Akt signaling pathway.
Christine C Tomlinson ... Blossom Damania
J Virol 2004 Feb; 78(4)1918-27.

Score: 0.445
Pleiotropic signal transduction mediated by human CD30: a member of the tumor necrosis factor receptor (TNFR) family.
Christof Schneider ... Gabriele Hübinger
Leuk Lymphoma 2002 Jul; 43(7)1355-66.

Score: 0.436
The machinery of programmed cell death.
K C Zimmermann ... D R Green
Pharmacol Ther 2001 Oct; 92(1)57-70.

Score: 0.435
Interleukin-1/Toll receptor family members: receptor structure and signal transduction pathways.
J M Daun ... M J Fenton
J Interferon Cytokine Res 2000 Oct; 20(10)843-55.

Score: 0.435
CD40 induces apoptosis in carcinoma cells through activation of cytotoxic ligands of the tumor necrosis factor superfamily.
A G Eliopoulos ... L S Young
Mol Cell Biol 2000 Aug; 20(15)5503-15.

Score: 0.435
To die or not to die--the quest of the TRAIL receptors.
M Degli-Esposti
J Leukoc Biol 1999 May; 65(5)535-42.

Score: 0.434
Assembly of post-receptor signaling complexes for the tumor necrosis factor receptor superfamily.
Hao Wu
Adv Protein Chem 2004 ; 68()225-79.

Score: 0.434
Role of tumor necrosis factor (TNF) receptor-associated factor 2 (TRAF2) in distinct and overlapping CD40 and TNF receptor 2/CD120b-mediated B lymphocyte activation.
Melissa E Munroe ... Gail A Bishop
J Biol Chem 2004 Dec; 279(51)53222-31.

Score: 0.434
The DAP kinase family of pro-apoptotic proteins: novel players in the apoptotic game.
D Kögel ... K H Scheidtmann
Bioessays 2001 Apr; 23(4)352-8.

Score: 0.434
Apoptosis signaling by death receptors.
K Schulze-Osthoff ... M E Peter
Eur J Biochem 1998 Jun; 254(3)439-59.

Score: 0.433
RIP2 is a novel NF-kappaB-activating and cell death-inducing kinase.
J V McCarthy ... V M Dixit
J Biol Chem 1998 Jul; 273(27)16968-75.

Score: 0.433
TRAF-interacting protein (TRIP): a novel component of the tumor necrosis factor receptor (TNFR)- and CD30-TRAF signaling complexes that inhibits TRAF2-mediated NF-kappaB activation.
S Y Lee ... Y Choi
J Exp Med 1997 Apr; 185(7)1275-85.

Score: 0.432
Targeting death receptors in bladder, prostate and renal cancer.
Hugh F O'Kane ... Kate E Williamson
J Urol 2006 Feb; 175(2)432-8.

Score: 0.431
TRAIL and apoptosis induction by TNF-family death receptors.
Shulin Wang ... Wafik S El-Deiry
Oncogene 2003 Nov; 22(53)8628-33.

Score: 0.431
The receptor for the cytotoxic ligand TRAIL.
G Pan ... V M Dixit
Science 1997 Apr; 276(5309)111-3.

Score: 0.429
TRAIL and NFkappaB signaling--a complex relationship.
Harald Wajant
Vitam Horm 2004 ; 67()101-32.

Score: 0.428
Biochemical pathways of caspase activation during apoptosis.
I Budihardjo ... X Wang
Annu Rev Cell Dev Biol 1999 ; 15()269-90.

Score: 0.428
FADD/MORT1 and caspase-8 are recruited to TRAIL receptors 1 and 2 and are essential for apoptosis mediated by TRAIL receptor 2.
M R Sprick ... H Walczak
Immunity 2000 Jun; 12(6)599-609.

Score: 0.426
KILLER/DR5, a novel DNA-damage inducible death receptor gene, links the p53-tumor suppressor to caspase activation and apoptotic death.
G S Wu ... W S el-Deiry
Adv Exp Med Biol 2000 ; 465()143-51.

Score: 0.421
Apoptosis and its relevance in cancer therapy.
J E Ehlert ... M H Kubbutat
Onkologie 2001 Oct; 24(5)433-40.

Score: 0.419
Tumor necrosis factor (TNF)-alpha and TNF receptors in viral pathogenesis.
G Herbein ... W A O'Brien
Proc Soc Exp Biol Med 2000 Mar; 223(3)241-57.

Score: 0.419
Fas triggers an alternative, caspase-8-independent cell death pathway using the kinase RIP as effector molecule.
N Holler ... J Tschopp
Nat Immunol 2000 Dec; 1(6)489-95.

Score: 0.419
TNF receptor associated factors in cytokine signaling.
H Wajant ... P Scheurich
Cytokine Growth Factor Rev 1999 Mar; 10(1)15-26.

Score: 0.416
Death receptor-induced cell killing.
Andrew Thorburn
Cell Signal 2004 Feb; 16(2)139-44.

Score: 0.416
Apoptosis induced by death receptors.
P Schneider ... J Tschopp
Pharm Acta Helv 2000 Mar; 74(2-3)281-6.

Score: 0.415
Pathways to caspase activation.
Zi-Bing Wang ... Yu-Fang Cui
Cell Biol Int 2005 Jul; 29(7)489-96.

Score: 0.413
Enhanced proliferation and increased IFN-gamma production in T cells by signal transduced through TNF-related apoptosis-inducing ligand.
A H Chou ... P N Hsu
J Immunol 2001 Aug; 167(3)1347-52.

Score: 0.413
G-protein-coupled receptor of Kaposi's sarcoma-associated herpesvirus is a viral oncogene and angiogenesis activator.
C Bais ... M C Gerhengorn
Nature 1998 Jan; 391(6662)86-9.

Score: 0.412
The TNF-TNF receptor system.
Thomas Hehlgans ... Daniela N Männel
Biol Chem 2002 Oct; 383(10)1581-5.

Score: 0.412
Fas-associated death domain protein and caspase-8 are not recruited to the tumor necrosis factor receptor 1 signaling complex during tumor necrosis factor-induced apoptosis.
Nicholas Harper ... Gerald M Cohen
J Biol Chem 2003 Jul; 278(28)25534-41.

Score: 0.410
Messengers of cell death: apoptotic signaling in health and disease.
Davide Rossi ... Gianluca Gaidano
Haematologica 2003 Feb; 88(2)212-8.

Score: 0.409
A novel family of viral death effector domain-containing molecules that inhibit both CD-95- and tumor necrosis factor receptor-1-induced apoptosis.
S Hu ... V M Dixit
J Biol Chem 1997 Apr; 272(15)9621-4.

Score: 0.408
The human herpes virus 8-encoded viral FLICE-inhibitory protein induces cellular transformation via NF-kappaB activation.
Qinmiao Sun ... Preet M Chaudhary
J Biol Chem 2003 Dec; 278(52)52437-45.

Score: 0.408
Apo-3, a new member of the tumor necrosis factor receptor family, contains a death domain and activates apoptosis and NF-kappa B.
S A Marsters ... A Ashkenazi
Curr Biol 1996 Dec; 6(12)1669-76.

Score: 0.408
Functional diversity and regulation of different interleukin-1 receptor-associated kinase (IRAK) family members.
Sophie Janssens ... Rudi Beyaert
Mol Cell 2003 Feb; 11(2)293-302.

Score: 0.406
Systematic mutational analysis of the death domain of the tumor necrosis factor receptor 1-associated protein TRADD.
A Park ... V R Baichwal
J Biol Chem 1996 Apr; 271(16)9858-62.

Score: 0.404
Constitutive NF-kappaB activation, normal Fas-induced apoptosis, and increased incidence of lymphoma in human herpes virus 8 K13 transgenic mice.
Priti Chugh ... Preet M Chaudhary
Proc Natl Acad Sci U S A 2005 Sep; 102(36)12885-90.

Score: 0.403
Kaposi's sarcoma-associated herpesvirus encoded vFLIP induces cellular IL-6 expression: the role of the NF-kappaB and JNK/AP1 pathways.
Jiabin An ... Matthew B Rettig
Oncogene 2003 May; 22(22)3371-85.

Score: 0.403
The CD95 type I/type II model.
Bryan C Barnhart ... Marcus E Peter
Semin Immunol 2003 Jun; 15(3)185-93.

Score: 0.403
Effects of antisense oligonucleotide-mediated depletion of tumor necrosis factor (TNF) receptor 1-associated death domain protein on TNF-induced gene expression.
Andrew M Siwkowski ... Brenda F Baker
Mol Pharmacol 2004 Sep; 66(3)572-9.

Score: 0.402
Tumor necrosis factor-related apoptosis-inducing ligand receptors signal NF-kappaB and JNK activation and apoptosis through distinct pathways.
W H Hu ... H B Shu
J Biol Chem 1999 Oct; 274(43)30603-10.

Score: 0.402
ATAR, a novel tumor necrosis factor receptor family member, signals through TRAF2 and TRAF5.
H Hsu ... W J Boyle
J Biol Chem 1997 May; 272(21)13471-4.

Score: 0.402
Expression and function of death receptors and their natural ligands in the intestine.
J Sträter ... P Möller
Ann N Y Acad Sci 2000 ; 915()162-70.

Score: 0.402
Infrequent mutation of TRAIL receptor 2 (TRAIL-R2/DR5) in transitional cell carcinoma of the bladder with 8p21 loss of heterozygosity.
Jacqui Adams ... Margaret A Knowles
Cancer Lett 2005 Apr; 220(2)137-44.

Score: 0.398
Apoptotic signaling pathways: caspases and stress-activated protein kinases.
Ssang-Goo Cho ... Eui-Ju Choi
J Biochem Mol Biol 2002 Jan; 35(1)24-7.

Score: 0.398
Herpesvirus entry mediator, a member of the tumor necrosis factor receptor (TNFR) family, interacts with members of the TNFR-associated factor family and activates the transcription factors NF-kappaB and AP-1.
S A Marsters ... A Ashkenazi
J Biol Chem 1997 May; 272(22)14029-32.

Score: 0.396
[Intracellular signal transduction pathway and its relation to lymphomagenesis]
S Ohtake
Nippon Rinsho 2000 Mar; 58(3)529-34.

Score: 0.395
Virocrine transformation: the intersection between viral transforming proteins and cellular signal transduction pathways.
D DiMaio ... O Klein
Annu Rev Microbiol 1998 ; 52()397-421.

Score: 0.394
Signal transduction by DR3, a death domain-containing receptor related to TNFR-1 and CD95.
A M Chinnaiyan ... V M Dixit
Science 1996 Nov; 274(5289)990-2.

Score: 0.394
TNF/TNFR family members in costimulation of T cell responses.
Tania H Watts
Annu Rev Immunol 2005 ; 23()23-68.

Score: 0.394
Receptor activator of NF-kappaB recruits multiple TRAF family adaptors and activates c-Jun N-terminal kinase.
H H Kim ... Z H Lee
FEBS Lett 1999 Jan; 443(3)297-302.

Score: 0.393
The kiss of death: promises and failures of death receptors and ligands in cancer therapy.
P T Daniel ... K Schulze-Osthoff
Leukemia 2001 Jul; 15(7)1022-32.

Score: 0.392
[Animal ontogenetic cell signaling pathways by the example of Notch cascade of Drosophila melanogaster]
N Ia Vaĭsman
Zh Obshch Biol 2004 Jul-Aug; 65(4)322-33.

Score: 0.390
Receptor-mediated choreography of life and death.
Anjana Bhardwaj ... Bharat B Aggarwal
J Clin Immunol 2003 Sep; 23(5)317-32.

Score: 0.390
Signaling pathways mediated by tumor necrosis factor alpha.
K G Leong ... A Karsan
Histol Histopathol 2000 Oct; 15(4)1303-25.

Score: 0.390
Kaposi's sarcoma-associated herpesvirus-encoded oncogenes and oncogenesis.
P S Moore ... Y Chang
J Natl Cancer Inst Monogr 1998 ; (23)65-71.

Score: 0.389
The tumor necrosis factor signaling complex: choosing a path toward cell death or cell proliferation.
K Warzocha ... G Salles
Leuk Lymphoma 1998 Mar; 29(1-2)81-92.

Score: 0.389
LMP1 signal transduction differs substantially from TNF receptor 1 signaling in the molecular functions of TRADD and TRAF2.
A Kieser ... W Hammerschmidt
EMBO J 1999 May; 18(9)2511-21.

Score: 0.388
Human normal hepatocytes are susceptible to apoptosis signal mediated by both TRAIL-R1 and TRAIL-R2.
E Mori ... S Kataoka
Cell Death Differ 2004 Feb; 11(2)203-7.

Score: 0.388
Exploring cell death mechanisms by analyzing signaling cascades of the TNF/NGF receptor family.
D Wallach ... E Varfolomeev
Behring Inst Mitt 1996 Oct; (97)144-55.

Score: 0.388
Induction of cell death by tumour necrosis factor (TNF) receptor 2, CD40 and CD30: a role for TNF-R1 activation by endogenous membrane-anchored TNF.
M Grell ... A Strasser
EMBO J 1999 Jun; 18(11)3034-43.

Score: 0.388
p53-dependent impairment of T-cell proliferation in FADD dominant-negative transgenic mice.
M Zörnig ... G Evan
Curr Biol 1998 Apr; 8(8)467-70.

Score: 0.388
Deciphering the pathways of life and death.
H Li ... J Yuan
Curr Opin Cell Biol 1999 Apr; 11(2)261-6.

Score: 0.388
Characterization of a p75(NTR) apoptotic signaling pathway using a novel cellular model.
X Wang ... C Vincenz
J Biol Chem 2001 Sep; 276(36)33812-20.

Score: 0.388
TRUNDD, a new member of the TRAIL receptor family that antagonizes TRAIL signalling.
G Pan ... V M Dixit
FEBS Lett 1998 Mar; 424(1-2)41-5.

Score: 0.388
An apoptosis signaling pathway induced by the death domain of FADD selectively kills normal but not cancerous prostate epithelial cells.
M J Morgan ... A Thorburn
Cell Death Differ 2001 Jul; 8(7)696-705.

Score: 0.387
TRICK2, a new alternatively spliced receptor that transduces the cytotoxic signal from TRAIL.
G R Screaton ... J I Bell
Curr Biol 1997 Sep; 7(9)693-6.

Score: 0.387
Induction of signaling pathways by herpes simplex virus type 1 through glycoprotein H peptides.
Stefania Galdiero ... Ettore Benedetti
Biopolymers 2004 ; 76(6)494-502.

Score: 0.387
Direct binding of Fas-associated death domain (FADD) to the tumor necrosis factor-related apoptosis-inducing ligand receptor DR5 is regulated by the death effector domain of FADD.
Lance R Thomas ... Andrew Thorburn
J Biol Chem 2004 Jul; 279(31)32780-5.

Score: 0.386
How are the regulators regulated? The search for mechanisms that impose specificity on induction of cell death and NF-kappaB activation by members of the TNF/NGF receptor family.
David Wallach ... Si Qing Zhang
Arthritis Res 2002 ; 4 Suppl 3()S189-96.

Score: 0.386
The Stat family in cytokine signaling.
J N Ihle
Curr Opin Cell Biol 2001 Apr; 13(2)211-7.

Score: 0.386
Hepatitis C virus core protein binds to the cytoplasmic domain of tumor necrosis factor (TNF) receptor 1 and enhances TNF-induced apoptosis.
N Zhu ... M M Lai
J Virol 1998 May; 72(5)3691-7.

Score: 0.385
c-E10 is a caspase-recruiting domain-containing protein that interacts with components of death receptors signaling pathway and activates nuclear factor-kappaB.
A Costanzo ... P Vito
J Biol Chem 1999 Jul; 274(29)20127-32.

Score: 0.385
The Kaposi's sarcoma-associated herpes virus G protein-coupled receptor up-regulates vascular endothelial growth factor expression and secretion through mitogen-activated protein kinase and p38 pathways acting on hypoxia-inducible factor 1alpha.
A Sodhi ... J S Gutkind
Cancer Res 2000 Sep; 60(17)4873-80.

Score: 0.385
How cells die: apoptosis pathways.
K C Zimmermann ... D R Green
J Allergy Clin Immunol 2001 Oct; 108(4 Suppl)S99-103.

Score: 0.385
Death the Fas way: regulation and pathophysiology of CD95 and its ligand.
K Sharma ... Y F Shi
Pharmacol Ther 2000 Dec; 88(3)333-47.

Score: 0.385
Life and death decisions: secondary complexes and lipid rafts in TNF receptor family signal transduction.
Jagan R Muppidi ... Richard M Siegel
Immunity 2004 Oct; 21(4)461-5.

Score: 0.384
[TNF/TNFR gene and apoptosis]
Y Takeda ... F Sendo
Nippon Rinsho 1996 Jul; 54(7)1888-94.

Score: 0.384
Transformation by oncogenic RAS sensitizes human colon cells to TRAIL-induced apoptosis by up-regulating death receptor 4 and death receptor 5 through a MEK-dependent pathway.
Konstantinos G Drosopoulos ... Alexander Pintzas
J Biol Chem 2005 Jun; 280(24)22856-67.

Score: 0.384
Xenopus death receptor-M1 and -M2, new members of the tumor necrosis factor receptor superfamily, trigger apoptotic signaling by differential mechanisms.
Kei Tamura ... Michihiko Ito
J Biol Chem 2004 Feb; 279(9)7629-35.

Score: 0.384
The C-terminal tails of tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) and Fas receptors have opposing functions in Fas-associated death domain (FADD) recruitment and can regulate agonist-specific mechanisms of receptor activation.
Lance R Thomas ... Andrew Thorburn
J Biol Chem 2004 Dec; 279(50)52479-86.

Score: 0.383
The KSHV G protein-coupled receptor signals via multiple pathways to induce transcription factor activation in primary effusion lymphoma cells.
Mark L Cannon ... Ethels Cesarman
Oncogene 2004 Jan; 23(2)514-23.

Score: 0.383
Molecular mechanisms of death-receptor-mediated apoptosis.
U Sartorius ... P H Krammer
Chembiochem 2001 Jan; 2(1)20-9.

Score: 0.383
Multiple signal transduction pathways activated through the T cell receptor for antigen.
J N Siegel ... L E Samelson
Semin Immunol 1991 Sep; 3(5)325-34.

Score: 0.383
Regulation of growth signalling and cell cycle by Kaposi's sarcoma-associated herpesvirus genes.
Shamindra Direkze ... Heike Laman
Int J Exp Pathol 2004 Dec; 85(6)305-19.

Score: 0.383
Tumor necrosis factor receptor and Fas signaling mechanisms.
D Wallach ... M P Boldin
Annu Rev Immunol 1999 ; 17()331-67.

Score: 0.382
TRAIL and viral infection.
Jörn Sträter ... Peter Möller
Vitam Horm 2004 ; 67()257-74.

Score: 0.382
Death receptor signals to mitochondria.
Roya Khosravi-Far ... Mauro Degli Esposti
Cancer Biol Ther 2004 Nov; 3(11)1051-7.

Score: 0.382
Tumour necrosis factor-mediated cell death pathways do not contribute to muscle fibre death in dystrophinopathies.
Dominique S Tews
Acta Neuropathol (Berl) 2005 Feb; 109(2)217-25.

Score: 0.381
TRAIL/Apo2L activates c-Jun NH2-terminal kinase (JNK) via caspase-dependent and caspase-independent pathways.
F Mühlenbeck ... H Wajant
J Biol Chem 1998 Dec; 273(49)33091-8.

Score: 0.381
Molecular determinants of kinase pathway activation by Apo2 ligand/tumor necrosis factor-related apoptosis-inducing ligand.
Eugene Varfolomeev ... Avi Ashkenazi
J Biol Chem 2005 Dec; 280(49)40599-608.

Score: 0.380
Identification and characterization of a new member of the TNF family that induces apoptosis.
S R Wiley ... C A Smith
Immunity 1995 Dec; 3(6)673-82.

Score: 0.379
The role of apoptosis signal-regulating kinase 1 in lymphotoxin-beta receptor-mediated cell death.
Mei-Chieh Chen ... Shie-Liang Hsieh
J Biol Chem 2003 May; 278(18)16073-81.

Score: 0.379
Murine TRAIL (TNF-related apoptosis inducing ligand) expression induced by T cell activation is blocked by rapamycin, cyclosporin A, and inhibitors of phosphatidylinositol 3-kinase, protein kinase C, and protein tyrosine kinases: evidence for TRAIL induction via the T cell receptor signaling pathway.
B L Musgrave ... D W Hoskin
Exp Cell Res 1999 Oct; 252(1)96-103.

Score: 0.379
Epidermal growth factor and trail interactions in epithelial-derived cells.
Spencer Bruce Gibson
Vitam Horm 2004 ; 67()207-27.

Score: 0.379
Death receptor-induced activation of initiator caspase 8 is antagonized by serine/threonine kinase PAK4.
Nerina Gnesutta ... Audrey Minden
Mol Cell Biol 2003 Nov; 23(21)7838-48.

Score: 0.378
RELT, a new member of the tumor necrosis factor receptor superfamily, is selectively expressed in hematopoietic tissues and activates transcription factor NF-kappaB.
G L Sica ... L Chen
Blood 2001 May; 97(9)2702-7.

Score: 0.378
Intracellular mechanisms of TRAIL: apoptosis through mitochondrial-dependent and -independent pathways.
A Suliman ... R K Srivastava
Oncogene 2001 Apr; 20(17)2122-33.

Score: 0.378
Targeted induction of apoptosis in cancer management: the emerging role of tumor necrosis factor-related apoptosis-inducing ligand receptor activating agents.
Eric K Rowinsky
J Clin Oncol 2005 Dec; 23(36)9394-407.

Score: 0.378
Transducing signals of life and death.
J Yuan
Curr Opin Cell Biol 1997 Apr; 9(2)247-51.

Score: 0.378
Initiation of angiogenic Kaposi's sarcoma lesions.
Gary S Hayward
Cancer Cell 2003 Jan; 3(1)1-3.

Score: 0.377
TRAIL receptor-selective mutants signal to apoptosis via TRAIL-R1 in primary lymphoid malignancies.
Marion MacFarlane ... Gerald M Cohen
Cancer Res 2005 Dec; 65(24)11265-70.

Score: 0.377
Tumor necrosis factor receptor-associated factors (TRAFs).
J R Bradley ... J S Pober
Oncogene 2001 Oct; 20(44)6482-91.

Score: 0.377
TRAF4 functions as an intermediate of GITR-induced NF-kappaB activation.
E M Esparza ... R H Arch
Cell Mol Life Sci 2004 Dec; 61(24)3087-92.

Score: 0.377
Fas-associated death domain protein (FADD) and caspase-8 mediate up-regulation of c-Fos by Fas ligand and tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) via a FLICE inhibitory protein (FLIP)-regulated pathway.
D Siegmund ... H Wajant
J Biol Chem 2001 Aug; 276(35)32585-90.

Score: 0.376
Death of HT29 adenocarcinoma cells induced by TNF family receptor activation is caspase-independent and displays features of both apoptosis and necrosis.
C A Wilson ... J L Browning
Cell Death Differ 2002 Dec; 9(12)1321-33.

Score: 0.375
Additive effects of PDGF receptor beta signaling pathways in vascular smooth muscle cell development.
Michelle D Tallquist ... Philippe Soriano
PLoS Biol 2003 Nov; 1(2)E52.

Score: 0.375
Cell surface Death Receptor signaling in normal and cancer cells.
Nesrin Ozören ... Wafik S El-Deiry
Semin Cancer Biol 2003 Apr; 13(2)135-47.

Score: 0.375
Fas and tumor necrosis factor receptor-mediated cell death: similarities and distinctions.
M V Clement ... I Stamenkovic
J Exp Med 1994 Aug; 180(2)557-67.

Score: 0.374
TRAIL and its receptors in the colonic epithelium: a putative role in the defense of viral infections.
Jörn Sträter ... Peter Möller
Gastroenterology 2002 Mar; 122(3)659-66.

Score: 0.374
Modulation of the NF-kappa B pathway by virally encoded death effector domains-containing proteins.
P M Chaudhary ... L Hood
Oncogene 1999 Oct; 18(42)5738-46.

Score: 0.374
Immortalization of primary endothelial cells by the K1 protein of Kaposi's sarcoma-associated herpesvirus.
Ling Wang ... Blossom Damania
Cancer Res 2006 Apr; 66(7)3658-66.

Score: 0.374
Reovirus-induced apoptosis requires both death receptor- and mitochondrial-mediated caspase-dependent pathways of cell death.
D J Kominsky ... K L Tyler
Cell Death Differ 2002 Sep; 9(9)926-33.

Score: 0.374
Transducers of life and death: TNF receptor superfamily and associated proteins.
S J Baker ... E P Reddy
Oncogene 1996 Jan; 12(1)1-9.

Score: 0.374
Control of TRAIL-induced apoptosis by a family of signaling and decoy receptors.
J P Sheridan ... A Ashkenazi
Science 1997 Aug; 277(5327)818-21.

Score: 0.373
Death receptors and apoptosis. Deadly signaling and evasive tactics.
C Vincenz
Cardiol Clin 2001 Feb; 19(1)31-43.

Score: 0.373
Translocation of TRAF proteins regulates apoptotic threshold of cells.
R H Arch ... C B Thompson
Biochem Biophys Res Commun 2000 Jun; 272(3)936-45.

Score: 0.373
Bax and other pro-apoptotic Bcl-2 family "killer-proteins" and their victim the mitochondrion.
B Antonsson
Cell Tissue Res 2001 Dec; 306(3)347-61.

Score: 0.373
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The Jak-STAT pathway: specific signal transduction from the cell membrane to the nucleus.
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