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FRISC: The Faculty Research Interests Science Comparator
Yuh Min Chook, Ph.D.
Assistant Professor of Pharmacology
Molecular
Biophysics
Email: chooky@rockvax.rockefeller.edu
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Selected Publications
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Results - FULL MEDLINE:
Nucleocytoplasmic transport of proteins and control of cellular function.
V K Parnaik
Indian J Biochem Biophys 1996 Jun; 33(3)164-7.
Score: 0.625
Nucleocytoplasmic transport.
D Görlich ... I W Mattaj
Science 1996 Mar; 271(5255)1513-8.
Score: 0.624
Mechanisms of receptor-mediated nuclear import and nuclear export.
Lucy F Pemberton ... Bryce M Paschal
Traffic 2005 Mar; 6(3)187-98.
Score: 0.591
Directed inhibition of nuclear import in cellular hypertrophy.
C Perez-Terzic ... A Terzic
J Biol Chem 2001 Jun; 276(23)20566-71.
Score: 0.589
Nucleocytoplasmic transport: the soluble phase.
I W Mattaj ... L Englmeier
Annu Rev Biochem 1998 ; 67()265-306.
Score: 0.589
Karyopherins and nuclear import.
Y M Chook ... G Blobel
Curr Opin Struct Biol 2001 Dec; 11(6)703-15.
Score: 0.589
The carboxyl terminus of RNA helicase A contains a bidirectional nuclear transport domain.
H Tang ... F Wong-Staal
Mol Cell Biol 1999 May; 19(5)3540-50.
Score: 0.587
The nuclear pore complex: mediator of translocation between nucleus and cytoplasm.
T D Allen ... M W Goldberg
J Cell Sci 2000 May; 113 ( Pt 10)()1651-9.
Score: 0.587
Nucleocytoplasmic protein traffic and its significance to cell function.
Y Yoneda
Genes Cells 2000 Oct; 5(10)777-87.
Score: 0.585
The nuclear pore complex.
L I Davis
Annu Rev Biochem 1995 ; 64()865-96.
Score: 0.583
Qualitative highly divergent nuclear export signals can regulate export by the competition for transport cofactors in vivo.
P Heger ... R H Stauber
Traffic 2001 Aug; 2(8)544-55.
Score: 0.579
Nucleocytoplasmic transport enters the atomic age.
E Conti ... E Izaurralde
Curr Opin Cell Biol 2001 Jun; 13(3)310-9.
Score: 0.573
Nuclear import and export: transport factors, mechanisms and regulation.
J Moroianu
Crit Rev Eukaryot Gene Expr 1999 ; 9(2)89-106.
Score: 0.572
Nuclear transport mechanisms.
B B Quimby ... A H Corbett
Cell Mol Life Sci 2001 Nov; 58(12-13)1766-73.
Score: 0.565
Structural basis for the assembly of a nuclear export complex.
Yoshiyuki Matsuura ... Murray Stewart
Nature 2004 Dec; 432(7019)872-7.
Score: 0.565
Nucleocytoplasmic transport: factors and mechanisms.
G Simos ... E C Hurt
FEBS Lett 1995 Aug; 369(1)107-12.
Score: 0.562
Regulation of nuclear import and export by the GTPase Ran.
Susanne M Steggerda ... Bryce M Paschal
Int Rev Cytol 2002 ; 217()41-91.
Score: 0.561
Transport of macromolecules between the nucleus and the cytoplasm.
E Izaurralde ... S Adam
RNA 1998 Apr; 4(4)351-64.
Score: 0.561
Nucleocytoplasmic transport of macromolecules.
A H Corbett ... P A Silver
Microbiol Mol Biol Rev 1997 Jun; 61(2)193-211.
Score: 0.561
Nuclear export of proteins and RNAs.
S Nakielny ... G Dreyfuss
Curr Opin Cell Biol 1997 Jun; 9(3)420-9.
Score: 0.560
Optical recording of signal-mediated protein transport through single nuclear pore complexes.
O Keminer ... R Peters
Proc Natl Acad Sci U S A 1999 Oct; 96(21)11842-7.
Score: 0.560
Macromolecular exchanges between the nucleus and cytoplasm.
C M Feldherr
J Cell Biochem Suppl 1998 ; 30-31()214-9.
Score: 0.560
Reconstitution of HIV-1 rev nuclear export: independent requirements for nuclear import and export.
D C Love ... J A Hanover
Proc Natl Acad Sci U S A 1998 Sep; 95(18)10608-13.
Score: 0.558
Nuclear import and export pathways.
J Moroianu
J Cell Biochem 1999 ; Suppl 32-33()76-83.
Score: 0.558
The K nuclear shuttling domain: a novel signal for nuclear import and nuclear export in the hnRNP K protein.
W M Michael ... G Dreyfuss
EMBO J 1997 Jun; 16(12)3587-98.
Score: 0.557
Distinct nuclear import and export pathways mediated by members of the karyopherin beta family.
J Moroianu
J Cell Biochem 1998 Aug; 70(2)231-9.
Score: 0.552
Transport between the cell nucleus and the cytoplasm.
D Görlich ... U Kutay
Annu Rev Cell Dev Biol 1999 ; 15()607-60.
Score: 0.551
In or out? Regulating nuclear transport.
J K Hood ... P A Silver
Curr Opin Cell Biol 1999 Apr; 11(2)241-7.
Score: 0.549
Importin-beta-like nuclear transport receptors.
A C Ström ... K Weis
Genome Biol 2001 ; 2(6)REVIEWS3008.
Score: 0.548
Nuclear import and export of viruses and virus genomes.
G R Whittaker ... A Helenius
Virology 1998 Jun; 246(1)1-23.
Score: 0.547
The role of nuclear import and export in influenza virus infection.
G Whittaker ... A Helenius
Trends Cell Biol 1996 Feb; 6(2)67-71.
Score: 0.543
The direction of transport through the nuclear pore can be inverted.
M V Nachury ... K Weis
Proc Natl Acad Sci U S A 1999 Aug; 96(17)9622-7.
Score: 0.539
Nuclear pores and macromolecular assemblies involved in nucleocytoplasmic transport.
M Stewart ... W D Clarkson
Curr Opin Struct Biol 1996 Apr; 6(2)162-5.
Score: 0.538
Transport into and out of the nucleus.
I G Macara
Microbiol Mol Biol Rev 2001 Dec; 65(4)570-94, table of contents.
Score: 0.537
Nuclear import and export signals in control of the p53-related protein p73.
Tomomi Inoue ... Carl G Maki
J Biol Chem 2002 Apr; 277(17)15053-60.
Score: 0.536
Molecular trafficking across the nuclear pore complex.
L Gerace
Curr Opin Cell Biol 1992 Aug; 4(4)637-45.
Score: 0.532
Nucleocytoplasmic transport: signals, mechanisms and regulation.
E A Nigg
Nature 1997 Apr; 386(6627)779-87.
Score: 0.526
Protein and RNA export from the nucleus.
Elissa P Lei ... Pamela A Silver
Dev Cell 2002 Mar; 2(3)261-72.
Score: 0.525
Molecular mechanisms that regulate transcription factor localization suggest new targets for drug development.
Sang-Hyun Lee ... Mark Hannink
Adv Drug Deliv Rev 2003 Jun; 55(6)717-31.
Score: 0.524
Two-way trafficking with Ran.
F Melchior ... L Gerace
Trends Cell Biol 1998 May; 8(5)175-9.
Score: 0.521
The karyopherin Msn5/Kap142 requires Nup82 for nuclear export and performs a function distinct from translocation in RPA protein import.
Kenneth D Belanger ... Birthe Fahrenkrog
J Biol Chem 2004 Oct; 279(42)43530-9.
Score: 0.518
Nuclear import of IkappaBalpha is accomplished by a ran-independent transport pathway.
S Sachdev ... M Hannink
Mol Cell Biol 2000 Mar; 20(5)1571-82.
Score: 0.517
Transport of RNA between nucleus and cytoplasm.
E Izaurralde ... I W Mattaj
Semin Cell Biol 1992 Aug; 3(4)279-88.
Score: 0.517
Nuclear transport and transcriptional regulation.
P Turpin ... C Dargemont
FEBS Lett 1999 Jun; 452(1-2)82-6.
Score: 0.517
Signal-mediated nuclear transport in the amoeba.
C M Feldherr ... D Akin
J Cell Sci 1999 Jun; 112 ( Pt 12)()2043-8.
Score: 0.513
Analysis of nuclear targeting activities of transport signals in the human immunodeficiency virus Rev protein.
Séverine Demart ... Ruth Brack-Werner
Exp Cell Res 2003 Dec; 291(2)484-501.
Score: 0.513
A nuclear export signal in the N-terminal regulatory domain of IkappaBalpha controls cytoplasmic localization of inactive NF-kappaB/IkappaBalpha complexes.
T T Huang ... S Miyamoto
Proc Natl Acad Sci U S A 2000 Feb; 97(3)1014-9.
Score: 0.513
The HIV-1 Rev protein.
V W Pollard ... M H Malim
Annu Rev Microbiol 1998 ; 52()491-532.
Score: 0.512
Phosphorylation of the nuclear transport machinery down-regulates nuclear protein import in vitro.
R H Kehlenbach ... L Gerace
J Biol Chem 2000 Jun; 275(23)17848-56.
Score: 0.510
In vitro analysis of nuclear transport mediated by the C-terminal shuttle domain of Tap.
I Schmitt ... L Gerace
J Biol Chem 2001 Nov; 276(45)42355-63.
Score: 0.509
A distinct nuclear import pathway used by ribosomal proteins.
M P Rout ... J D Aitchison
Cell 1997 May; 89(5)715-25.
Score: 0.504
Nucleocytoplasmic transport: cargo trafficking across the border.
Karsten Weis
Curr Opin Cell Biol 2002 Jun; 14(3)328-35.
Score: 0.504
A novel system to quantitate nuclear-cytoplasmic flux in vivo: kinetics of signal-dependent nuclear protein export.
A Efthymiadis ... D A Jans
Arch Biochem Biophys 1998 Jul; 355(2)254-61.
Score: 0.503
Nucleocytoplasmic shuttling signals: two for the price of one.
W M Michael
Trends Cell Biol 2000 Feb; 10(2)46-50.
Score: 0.503
Signal-mediated nuclear export pathways of proteins and RNAs.
U Fischer ... G Dreyfuss
Trends Cell Biol 1996 Aug; 6(8)290-3.
Score: 0.502
Import and export of the nuclear protein import receptor transportin by a mechanism independent of GTP hydrolysis.
S Nakielny ... G Dreyfuss
Curr Biol 1998 Jan; 8(2)89-95.
Score: 0.501
A role for the M9 transport signal of hnRNP A1 in mRNA nuclear export.
E Izaurralde ... U Fischer
J Cell Biol 1997 Apr; 137(1)27-35.
Score: 0.501
Toward the molecular dissection of protein import into nuclei.
N Panté ... U Aebi
Curr Opin Cell Biol 1996 Jun; 8(3)397-406.
Score: 0.500
The mechanism of inhibition of Ran-dependent nuclear transport by cellular ATP depletion.
Eric D Schwoebel ... Mary Shannon Moore
J Cell Biol 2002 Jun; 157(6)963-74.
Score: 0.500
New steps toward the nucleocytoplasmic traffic of macromolecules.
Y Yoneda
Cell Struct Funct 2000 Aug; 25(4)205-6.
Score: 0.498
Exportin 4: a mediator of a novel nuclear export pathway in higher eukaryotes.
G Lipowsky ... D Görlich
EMBO J 2000 Aug; 19(16)4362-71.
Score: 0.497
Direct observation of nucleocytoplasmic transport by microinjection of GFP-tagged proteins in living cells.
O Rosorius ... R H Stauber
Biotechniques 1999 Aug; 27(2)350-5.
Score: 0.497
Nuclear transport.
E Fabre ... E C Hurt
Curr Opin Cell Biol 1994 Jun; 6(3)335-42.
Score: 0.497
Active nuclear import and export pathways regulate E2F-5 subcellular localization.
Margarita D Apostolova ... Lina Dagnino
J Biol Chem 2002 Sep; 277(37)34471-9.
Score: 0.496
Nuclear protein import.
D Görlich
Curr Opin Cell Biol 1997 Jun; 9(3)412-9.
Score: 0.494
Exogenously injected nuclear import factor p10/NTF2 inhibits signal-mediated nuclear import and export of proteins in living cells.
T Tachibana ... Y Yoneda
FEBS Lett 1996 Nov; 397(2-3)177-82.
Score: 0.493
Histone deacetylase 4 possesses intrinsic nuclear import and export signals.
A H Wang ... X J Yang
Mol Cell Biol 2001 Sep; 21(17)5992-6005.
Score: 0.493
Nucleocytoplasmic recycling of the nuclear localization signal receptor alpha subunit in vivo is dependent on a nuclear export signal, energy, and RCC1.
I Boche ... E Fanning
J Cell Biol 1997 Oct; 139(2)313-25.
Score: 0.493
Regulating access to the genome: nucleocytoplasmic transport throughout the cell cycle.
Karsten Weis
Cell 2003 Feb; 112(4)441-51.
Score: 0.492
Conformational variability of nucleo-cytoplasmic transport factors.
Noemi Fukuhara ... Dmitri Svergun
J Biol Chem 2004 Jan; 279(3)2176-81.
Score: 0.491
Nucleocytoplasmic transport: taking an inventory.
H Fried ... U Kutay
Cell Mol Life Sci 2003 Aug; 60(8)1659-88.
Score: 0.490
Receptor-mediated substrate translocation through the nuclear pore complex without nucleotide triphosphate hydrolysis.
L Englmeier ... I W Mattaj
Curr Biol 1999 Jan; 9(1)30-41.
Score: 0.488
Identification of a nuclear export receptor for tRNA.
G J Arts ... I W Mattaj
Curr Biol 1998 Mar; 8(6)305-14.
Score: 0.487
DNA binding domains in diverse nuclear receptors function as nuclear export signals.
B E Black ... B M Paschal
Curr Biol 2001 Nov; 11(22)1749-58.
Score: 0.487
Nuclear import and export of proteins: the molecular basis for intracellular signaling.
T Sekimoto ... Y Yoneda
Cytokine Growth Factor Rev 1998 Sep-Dec; 9(3-4)205-11.
Score: 0.486
Regulation of nuclear import and export.
T D Sweitzer ... J A Hanover
Curr Top Cell Regul 2000 ; 36()77-94.
Score: 0.486
Evidence for a role of CRM1 in signal-mediated nuclear protein export.
B Ossareh-Nazari ... C Dargemont
Science 1997 Oct; 278(5335)141-4.
Score: 0.484
Protein export from the nucleus.
B Ossareh-Nazari ... C Dargemont
Traffic 2001 Oct; 2(10)684-9.
Score: 0.484
The ins and outs of RNA nucleocytoplasmic transport.
M L Zapp
Curr Opin Genet Dev 1995 Apr; 5(2)229-33.
Score: 0.483
Identification of an NTF2-related factor that binds Ran-GTP and regulates nuclear protein export.
B E Black ... B M Paschal
Mol Cell Biol 1999 Dec; 19(12)8616-24.
Score: 0.483
Mediators of nuclear protein import target karyophilic proteins to pore complexes of cytoplasmic annulate lamellae.
V C Cordes ... S Reidenbach
Exp Cell Res 1997 Dec; 237(2)419-33.
Score: 0.479
Nuclear protein transport pathways.
M Köhler ... E Hartmann
Exp Nephrol 1999 Jul-Aug; 7(4)290-4.
Score: 0.479
Dissociation of nuclear import cargo complexes by the protein Ran: a fluorescence correlation spectroscopy study.
Cécile Fradin ... Michael Elbaum
C R Biol 2005 Dec; 328(12)1073-82.
Score: 0.478
Variations in signal-mediated nuclear transport during the cell cycle in BALB/c 3T3 cells.
C M Feldherr ... D Akin
Exp Cell Res 1994 Nov; 215(1)206-10.
Score: 0.478
Insights into a CRM1-mediated RNA-nuclear export pathway in Trypanosoma cruzi.
Ileana C Cuevas ... Iván D'Orso
Mol Biochem Parasitol 2005 Jan; 139(1)15-24.
Score: 0.476
Nuclear import and export of proteins in plants: a tool for the regulation of signalling.
T Merkle
Planta 2001 Aug; 213(4)499-517.
Score: 0.476
Nuclear transport: proliferating pathways.
D S Goldfarb
Curr Biol 1997 Jan; 7(1)R13-6.
Score: 0.476
Molecular mechanisms of nuclear protein transport.
J Moroianu
Crit Rev Eukaryot Gene Expr 1997 ; 7(1-2)61-72.
Score: 0.475
Nuclear RNA export.
Bryan R Cullen
J Cell Sci 2003 Feb; 116(Pt 4)587-97.
Score: 0.475
The asymmetric distribution of the constituents of the Ran system is essential for transport into and out of the nucleus.
E Izaurralde ... D Görlich
EMBO J 1997 Nov; 16(21)6535-47.
Score: 0.475
Nuclear transport and nuclear pores in yeast.
U Nehrbass ... E C Hurt
Antonie Van Leeuwenhoek 1992 Aug; 62(1-2)3-14.
Score: 0.471
Signals mediating nuclear targeting and their regulation: application in drug delivery.
D A Jans ... S Huebner
Med Res Rev 1998 Jul; 18(4)189-223.
Score: 0.471
Dynamic localization of the nuclear import receptor and its interactions with transport factors.
D M Koepp ... P A Silver
J Cell Biol 1996 Jun; 133(6)1163-76.
Score: 0.471
Translocation of beta-catenin into the nucleus independent of interactions with FG-rich nucleoporins.
Eun-Kyung Suh ... Barry M Gumbiner
Exp Cell Res 2003 Nov; 290(2)447-56.
Score: 0.471
In vitro analysis of nuclear mRNA export using molecular beacons for target detection.
Ralph H Kehlenbach
Nucleic Acids Res 2003 Jun; 31(11)e64.
Score: 0.471
Nucleocytoplasmic transport and nuclear envelope integrity in the fission yeast Schizosaccharomyces pombe.
Minoru Yoshida ... Shelley Sazer
Methods 2004 Jul; 33(3)226-38.
Score: 0.471
GLE2, a Saccharomyces cerevisiae homologue of the Schizosaccharomyces pombe export factor RAE1, is required for nuclear pore complex structure and function.
R Murphy ... S R Wente
Mol Biol Cell 1996 Dec; 7(12)1921-37.
Score: 0.471
Structural plasticity in influenza virus protein NS2 (NEP).
Barbara S Lommer ... Ming Luo
J Biol Chem 2002 Mar; 277(9)7108-17.
Score: 0.470
Nuclear import and export of influenza virus nucleoprotein.
G Neumann ... Y Kawaoka
J Virol 1997 Dec; 71(12)9690-700.
Score: 0.470
Nucleocytoplasmic protein transport and recycling of Ran.
Y Yoneda ... Y Miyamoto
Cell Struct Funct 1999 Dec; 24(6)425-33.
Score: 0.470
Nuclear export of proteins: the role of nuclear retention.
M S Schmidt-Zachmann ... E A Nigg
Cell 1993 Aug; 74(3)493-504.
Score: 0.468
Viral interactions with the nuclear transport machinery: discovering and disrupting pathways.
Beatriz Ma Fontoura ... Daniel R Nussenzveig
IUBMB Life 2005 Feb; 57(2)65-72.
Score: 0.468
Cytosolic import factor- and Ran-independent nuclear transport of ribosomal protein L5.
F Rudt ... T Pieler
Eur J Cell Biol 2001 Nov; 80(11)661-8.
Score: 0.467
Nucleo-cytoplasmic transport of proteins as a target for therapeutic drugs.
Yoko Yashiroda ... Minoru Yoshida
Curr Med Chem 2003 May; 10(9)741-8.
Score: 0.467
Transportin2 functions as importin and mediates nuclear import of HuR.
Stephan Güttinger ... Ulrike Kutay
Proc Natl Acad Sci U S A 2004 Mar; 101(9)2918-23.
Score: 0.467
A nuclear transport signal in mammalian target of rapamycin is critical for its cytoplasmic signaling to S6 kinase 1.
Rebecca A Bachmann ... Jie Chen
J Biol Chem 2006 Mar; 281(11)7357-63.
Score: 0.466
Switch from capsid protein import to adenovirus assembly by cleavage of nuclear transport signals.
Harald Wodrich ... Larry Gerace
EMBO J 2003 Dec; 22(23)6245-55.
Score: 0.466
Protein import into the nucleus: an integrated view.
G R Hicks ... N V Raikhel
Annu Rev Cell Dev Biol 1995 ; 11()155-88.
Score: 0.466
RNA nucleocytoplasmic transport.
M L Zapp
Semin Cell Biol 1992 Aug; 3(4)289-97.
Score: 0.465
Constitutive transport element-mediated nuclear export.
M L Hammarskjöld
Curr Top Microbiol Immunol 2001 ; 259()77-93.
Score: 0.465
Definition of a consensus transportin-specific nucleocytoplasmic transport signal.
H P Bogerd ... B R Cullen
J Biol Chem 1999 Apr; 274(14)9771-7.
Score: 0.464
Model system to study classical nuclear export signals.
Charu Kanwal ... Carol S Lim
AAPS PharmSci 2002 ; 4(3)E18.
Score: 0.464
Nucleocytoplasmic transport: Inside out regulation.
A K Hopper
Curr Biol 1999 Nov; 9(21)R803-6.
Score: 0.464
Bidirectional transport of glucocorticoid receptors across the nuclear envelope.
A P Madan ... D B DeFranco
Proc Natl Acad Sci U S A 1993 Apr; 90(8)3588-92.
Score: 0.461
Identification of novel import and export signals of human TAP, the protein that binds to the constitutive transport element of the type D retrovirus mRNAs.
J Bear ... B K Felber
Mol Cell Biol 1999 Sep; 19(9)6306-17.
Score: 0.460
Nuclear transport: a guide to import receptors.
L Yamasaki ... R E Lanford
Trends Cell Biol 1992 May; 2(5)123-7.
Score: 0.459
A G protein involved in nucleocytoplasmic transport: the role of Ran.
M S Moore ... G Blobel
Trends Biochem Sci 1994 May; 19(5)211-6.
Score: 0.459
The nuclear pore complex.
E C Hurt
FEBS Lett 1993 Jun; 325(1-2)76-80.
Score: 0.459
FRAP analysis of nucleocytoplasmic dynamics of the vitamin D receptor splice variant VDRB1: preferential targeting to nuclear speckles.
Kathryn L Sunn ... David A Jans
Biochem J 2005 Jun; 388(Pt 2)509-14.
Score: 0.459
Separate nuclear import pathways converge on the nucleoporin Nup153 and can be dissected with dominant-negative inhibitors.
S Shah ... D J Forbes
Curr Biol 1998 Dec 17-31; 8(25)1376-86.
Score: 0.459
The molecular structure of agrobacterium VirE2-single stranded DNA complexes involved in nuclear import.
V Citovsky ... J S Wall
J Mol Biol 1997 Sep; 271(5)718-27.
Score: 0.459
Taking from the cytoplasm and giving to the pore: soluble transport factors in nuclear protein import.
D J Sweet ... L Gerace
Trends Cell Biol 1995 Dec; 5(12)444-7.
Score: 0.458
A novel receptor-mediated nuclear protein import pathway.
V W Pollard ... G Dreyfuss
Cell 1996 Sep; 86(6)985-94.
Score: 0.458
Shuttling components of nuclear import machinery involved in nuclear translocation of steroid receptors exit nucleus via exportin-1/CRM-1* independent pathway.
Sanjay Kumar ... Rakesh K Tyagi
Biochim Biophys Acta 2004 May; 1691(2-3)73-7.
Score: 0.458
Gradient of increasing affinity of importin beta for nucleoporins along the pathway of nuclear import.
I Ben-Efraim ... L Gerace
J Cell Biol 2001 Jan; 152(2)411-7.
Score: 0.457
Regulation of nuclear import by phosphorylation adjacent to nuclear localization signals.
Michelle T Harreman ... Anita H Corbett
J Biol Chem 2004 May; 279(20)20613-21.
Score: 0.455
The human tap nuclear RNA export factor contains a novel transportin-dependent nuclear localization signal that lacks nuclear export signal function.
R Truant ... B R Cullen
J Biol Chem 1999 Nov; 274(45)32167-71.
Score: 0.455
Investigation of nucleo-cytoplasmic transport using UV-guided microinjection.
R H Stauber ... O Rosorius
J Cell Biochem 2001 ; 80(3)388-96.
Score: 0.455
Transportin-mediated nuclear import of heterogeneous nuclear RNP proteins.
M C Siomi ... G Dreyfuss
J Cell Biol 1997 Sep; 138(6)1181-92.
Score: 0.454
Nuclear transport of steroid hormone receptors.
Leonard C Shank ... Bryce M Paschal
Crit Rev Eukaryot Gene Expr 2005 ; 15(1)49-73.
Score: 0.454
SAC3 may link nuclear protein export to cell cycle progression.
A L Jones ... A H Corbett
Proc Natl Acad Sci U S A 2000 Mar; 97(7)3224-9.
Score: 0.454
Nuclear import and export signals in control of Nrf2.
Abhinav K Jain ... Anil K Jaiswal
J Biol Chem 2005 Aug; 280(32)29158-68.
Score: 0.453
Nuclear export of the E1B 55-kDa and E4 34-kDa adenoviral oncoproteins mediated by a rev-like signal sequence.
M Dobbelstein ... T Shenk
EMBO J 1997 Jul; 16(14)4276-84.
Score: 0.452
Nup2p, a yeast nucleoporin, functions in bidirectional transport of importin alpha.
J Solsbacher ... G Schlenstedt
Mol Cell Biol 2000 Nov; 20(22)8468-79.
Score: 0.451
Coupling of nuclear RNA export and protein import in vertebrate cells.
J E Dahlberg ... E Lund
Semin Cell Dev Biol 1997 Feb; 8(1)65-70.
Score: 0.451
Regulation of p53 localization.
S H Liang ... M F Clarke
Eur J Biochem 2001 May; 268(10)2779-83.
Score: 0.450
Analysis of the activity of nuclear export signals using fluorescent BSA conjugates.
Carl M Feldherr ... Debra Akin
Biotechniques 2002 Jun; 32(6)1288, 1290, 1292, 1294, 1296.
Score: 0.450
Karyopherins and kissing cousins.
R W Wozniak ... J D Aitchison
Trends Cell Biol 1998 May; 8(5)184-8.
Score: 0.450
The ran decathlon: multiple roles of Ran.
S Sazer ... M Dasso
J Cell Sci 2000 Apr; 113 ( Pt 7)()1111-8.
Score: 0.449
Nucleocytoplasmic translocation of Stat1 is regulated by a leucine-rich export signal in the coiled-coil domain.
A Begitt ... U Vinkemeier
Proc Natl Acad Sci U S A 2000 Sep; 97(19)10418-23.
Score: 0.449
Modulation of nuclear protein import: a novel means of regulating gene expression.
S M Fujihara ... S G Nadler
Biochem Pharmacol 1998 Jul; 56(2)157-61.
Score: 0.449
Genetic analysis of macromolecular transport across the nuclear envelope.
A Corbett ... P Silver
Exp Cell Res 1996 Dec; 229(2)212-6.
Score: 0.448
Regulation of nuclear translocation of extracellular signal-regulated kinase 5 by active nuclear import and export mechanisms.
Kunio Kondoh ... Eisuke Nishida
Mol Cell Biol 2006 Mar; 26(5)1679-90.
Score: 0.447
HNS, a nuclear-cytoplasmic shuttling sequence in HuR.
X C Fan ... J A Steitz
Proc Natl Acad Sci U S A 1998 Dec; 95(26)15293-8.
Score: 0.446
A photoregulated ligand for the nuclear import receptor karyopherin alpha.
S B Park ... R F Standaert
Bioorg Med Chem 2001 Dec; 9(12)3215-23.
Score: 0.445
A novel class of RanGTP binding proteins.
D Görlich ... E Izaurralde
J Cell Biol 1997 Jul; 138(1)65-80.
Score: 0.445
Characterization of the nuclear import and export functions of Ikappa B(epsilon).
Sang-Hyun Lee ... Mark Hannink
J Biol Chem 2002 Jun; 277(26)23358-66.
Score: 0.444
Molecular rearrangements within the nuclear pore complexes: a new way to regulate nucleocytoplasmic transport.
Valérie Doye
Dev Cell 2004 Jan; 6(1)1-3.
Score: 0.443
The karyopherin Kap142p/Msn5p mediates nuclear import and nuclear export of different cargo proteins.
K Yoshida ... G Blobel
J Cell Biol 2001 Feb; 152(4)729-40.
Score: 0.443
Borna disease virus nucleoprotein requires both nuclear localization and export activities for viral nucleocytoplasmic shuttling.
T Kobayashi ... K Ikuta
J Virol 2001 Apr; 75(7)3404-12.
Score: 0.442
Identification and functional characterization of a novel nuclear localization signal present in the yeast Nab2 poly(A)+ RNA binding protein.
R Truant ... B R Cullen
Mol Cell Biol 1998 Mar; 18(3)1449-58.
Score: 0.441
The 70-kD heat shock cognate protein (hsc70) facilitates the nuclear export of the import receptors.
Shingo Kose ... Naoko Imamoto
J Cell Biol 2005 Oct; 171(1)19-25.
Score: 0.440
The nuclear pore: at the crossroads.
J A Hanover
FASEB J 1992 Mar; 6(6)2288-95.
Score: 0.440
Review: transport of tRNA out of the nucleus-direct channeling to the ribosome?
H Grosshans ... E Hurt
J Struct Biol 2000 Apr; 129(2-3)288-94.
Score: 0.438
A Crm1p-independent nuclear export path for the mRNA-associated protein, Npl3p/Mtr13p.
Y Liu ... A M Tartakoff
Proc Natl Acad Sci U S A 1999 Jun; 96(12)6739-44.
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ERF nuclear shuttling, a continuous monitor of Erk activity that links it to cell cycle progression.
Lionel Le Gallic ... George Mavrothalassitis
Mol Cell Biol 2004 Feb; 24(3)1206-18.
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Nuclear protein import in permeabilized mammalian cells requires soluble cytoplasmic factors.
S A Adam ... L Gerace
J Cell Biol 1990 Sep; 111(3)807-16.
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beta-Catenin shows an overlapping sequence requirement but distinct molecular interactions for its bidirectional passage through nuclear pores.
Makiko Koike ... Naoko Imamoto
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Nuclear export: DNA-binding domains find a surprising partner.
D B DeFranco
Curr Biol 2001 Dec; 11(24)R1036-7.
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Interactions between HIV Rev and nuclear import and export factors: the Rev nuclear localisation signal mediates specific binding to human importin-beta.
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Nuclear export of mRNA: from the site of transcription to the cytoplasm.
Judith A Erkmann ... Ulrike Kutay
Exp Cell Res 2004 May; 296(1)12-20.
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The C-terminal domain of TAP interacts with the nuclear pore complex and promotes export of specific CTE-bearing RNA substrates.
A Bachi ... E Izaurralde
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The yeast nucleoporin Nup53p specifically interacts with Nic96p and is directly involved in nuclear protein import.
B Fahrenkrog ... U Aebi
Mol Biol Cell 2000 Nov; 11(11)3885-96.
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Nuclear localization signal peptides induce molecular delivery along microtubules.
Hanna Salman ... Michael Elbaum
Biophys J 2005 Sep; 89(3)2134-45.
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Protein export from the mitochondrial matrix.
R O Poyton ... G H Clarkson
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CRM1 is an export receptor for leucine-rich nuclear export signals.
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Cell 1997 Sep; 90(6)1051-60.
Score: 0.433
Signal sequences that target nuclear import and nuclear export of pre-mRNA-binding proteins.
W M Michael ... G Dreyfuss
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New ways to skin a kap: mechanisms for controlling nuclear transport.
C Patrick Lusk ... Richard W Wozniak
Biochem Cell Biol 2004 Dec; 82(6)618-25.
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Regulation of BRCA1, BRCA2 and BARD1 intracellular trafficking.
Beric R Henderson
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The POU protein Oct-6 is a nucleocytoplasmic shuttling protein.
Constanze Baranek ... Michael Wegner
Nucleic Acids Res 2005 ; 33(19)6277-86.
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Nuclear import and export functions in the different isoforms of the AUF1/heterogeneous nuclear ribonucleoprotein protein family.
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J Biol Chem 2003 Jun; 278(23)20700-7.
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A novel transferable nuclear export signal mediates CRM1-independent nucleocytoplasmic shuttling of the human cytomegalovirus transactivator protein pUL69.
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EMBO J 2001 Dec; 20(24)7271-83.
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The tumor suppressor p53 is subject to both nuclear import and export, and both are fast, energy-dependent and lectin-inhibited.
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Oncogene 1997 Mar; 14(12)1407-17.
Score: 0.430
The Drosophila nucleoporin DNup88 localizes DNup214 and CRM1 on the nuclear envelope and attenuates NES-mediated nuclear export.
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J Cell Biol 2003 Nov; 163(4)701-6.
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Requirement of guanosine triphosphate-bound ran for signal-mediated nuclear protein export.
S A Richards ... I G Macara
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Friedrich Miescher Prize awardee lecture review. A conserved family of nuclear export receptors mediates the exit of messenger RNA to the cytoplasm.
E Izaurralde
Cell Mol Life Sci 2001 Jul; 58(8)1105-12.
Score: 0.429
Kap120 functions as a nuclear import receptor for ribosome assembly factor Rpf1 in yeast.
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Mol Cell Biol 2006 Apr; 26(8)3170-80.
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The nucleoporin nup153 plays a critical role in multiple types of nuclear export.
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Mol Biol Cell 1999 Mar; 10(3)649-64.
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Nucleocytoplasmic shuttling of phospholipase C-delta1: a link to Ca2+.
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J Cell Biochem 2006 Feb; 97(2)233-43.
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Bidirectional on/off switch for controlled targeting of proteins to subcellular compartments.
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J Control Release 2004 Aug; 98(3)379-93.
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Evidence for specific nucleocytoplasmic transport pathways used by leucine-rich nuclear export signals.
C Elfgang ... D Bevec
Proc Natl Acad Sci U S A 1999 May; 96(11)6229-34.
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Importin 13: a novel mediator of nuclear import and export.
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EMBO J 2001 Jul; 20(14)3685-94.
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Nuclear import of Cdk/cyclin complexes: identification of distinct mechanisms for import of Cdk2/cyclin E and Cdc2/cyclin B1.
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J Cell Biol 1999 Jan; 144(2)213-24.
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Nuclear RNA export in yeast.
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The molecular mechanism of translocation through the nuclear pore complex is highly conserved.
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J Cell Sci 2002 Jul; 115(Pt 14)2997-3005.
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Eur J Cell Biol 2002 Oct; 81(10)549-56.
Score: 0.426
Nup50/Npap60 function in nuclear protein import complex disassembly and importin recycling.
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Communication between the cell membrane and the nucleus: role of protein compartmentalization.
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J Cell Biochem Suppl 1998 ; 30-31()250-63.
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Cofactor requirements for nuclear export of Rev response element (RRE)- and constitutive transport element (CTE)-containing retroviral RNAs. An unexpected role for actin.
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J Cell Biol 2001 Mar; 152(5)895-910.
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A lack of SUMO conjugation affects cNLS-dependent nuclear protein import in yeast.
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J Biol Chem 2002 Dec; 277(51)49554-61.
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Multiple vesiculoviral matrix proteins inhibit both nuclear export and import.
J M Petersen ... J E Dahlberg
Proc Natl Acad Sci U S A 2001 Jul; 98(15)8590-5.
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Requirements for the nuclear export of the small ribosomal subunit.
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J Cell Sci 2002 Jul; 115(Pt 14)2985-95.
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Identification of a signal for rapid export of proteins from the nucleus.
W Wen ... S S Taylor
Cell 1995 Aug; 82(3)463-73.
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Nuclear import of the stem-loop binding protein and localization during the cell cycle.
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Cell 2003 Dec; 115(7)813-23.
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Score: 0.423
A nuclear export signal prevents Saccharomyces cerevisiae Hsp70 Ssb1p from stimulating nuclear localization signal-directed nuclear transport.
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J Biol Chem 1999 Jun; 274(23)16501-7.
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Pathways for the nuclear transport of proteins and RNAs.
D Goldfarb ... N Michaud
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Yeast genetics to dissect the nuclear pore complex and nucleocytoplasmic trafficking.
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Annu Rev Genet 1997 ; 31()277-313.
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Nuclear export is evolutionarily conserved in CVC paired-like homeobox proteins and influences protein stability, transcriptional activation, and extracellular secretion.
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Mol Cell Biol 2005 Apr; 25(7)2573-82.
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Structure and function of the nuclear pore complex: new perspectives.
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Connections between the processing and nuclear export of mRNA: evidence for an export license?
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Proc Natl Acad Sci U S A 2000 Jan; 97(1)4-6.
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Regulation of protein transport to the nucleus: central role of phosphorylation.
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Physiol Rev 1996 Jul; 76(3)651-85.
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Nuclear export of Far1p in response to pheromones requires the export receptor Msn5p/Ste21p.
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Quantitative models of nuclear transport.
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Curr Opin Cell Biol 2005 Feb; 17(1)27-34.
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Adenoviral E1B-55kDa protein inhibits yeast mRNA export and perturbs nuclear structure.
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The yeast Apq12 protein affects nucleocytoplasmic mRNA transport.
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Ran GTPase: a master regulator of nuclear structure and function during the eukaryotic cell division cycle?
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Trends Cell Biol 2001 Sep; 11(9)366-71.
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Cellular requirements for CRM1 import and export.
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J Biochem (Tokyo) 2003 Nov; 134(5)759-64.
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Exportin 1 (Crm1p) is an essential nuclear export factor.
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Cell 1997 Sep; 90(6)1041-50.
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Nucleocytoplasmic transport: driving and directing transport.
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Curr Biol 1998 May; 8(11)R368-72.
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The dynamics of karyopherin-mediated nuclear transport.
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Biochem Cell Biol 2001 ; 79(5)603-12.
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Structural basis for nuclear import complex dissociation by RanGTP.
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Nature 2005 Jun; 435(7042)693-6.
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The influenza virus NEP (NS2 protein) mediates the nuclear export of viral ribonucleoproteins.
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EMBO J 1998 Jan; 17(1)288-96.
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Signal transduction. Marked for nuclear export?
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The ins and outs of STAT1 nuclear transport.
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Exportin 6: a novel nuclear export receptor that is specific for profilin.actin complexes.
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EMBO J 2003 Nov; 22(21)5928-40.
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Biogenesis of the signal recognition particle (SRP) involves import of SRP proteins into the nucleolus, assembly with the SRP-RNA, and Xpo1p-mediated export.
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J Cell Biol 2001 May; 153(4)745-62.
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Promotion of importin alpha-mediated nuclear import by the phosphorylation-dependent binding of cargo protein to 14-3-3.
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J Cell Biol 2005 May; 169(3)415-24.
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A Ran-independent pathway for export of spliced mRNA.
K N Clouse ... R Reed
Nat Cell Biol 2001 Jan; 3(1)97-9.
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CRM1- and Ran-independent nuclear export of beta-catenin.
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Curr Biol 2001 Jan; 11(1)18-27.
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Nucleocytoplasmic shuttling by protein nuclear import factors.
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Eur J Cell Biol 1998 Dec; 77(4)269-75.
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Nuclear mRNA export: insights from virology.
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Trends Biochem Sci 2003 Aug; 28(8)419-24.
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The mechanism of ran import into the nucleus by nuclear transport factor 2.
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J Biol Chem 2000 Sep; 275(37)28575-82.
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Structural plasticity of the cardiac nuclear pore complex in response to regulators of nuclear import.
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CDK phosphorylation of a novel NLS-NES module distributed between two subunits of the Mcm2-7 complex prevents chromosomal rereplication.
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Mol Biol Cell 2005 Oct; 16(10)5026-39.
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Nuclear pore localization and nucleocytoplasmic transport of eIF-5A: evidence for direct interaction with the export receptor CRM1.
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J Cell Sci 1999 Jul; 112 ( Pt 14)()2369-80.
Score: 0.411
The HECT ubiquitin ligase Rsp5p is required for proper nuclear export of mRNA in Saccharomyces cerevisiae.
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Influence of cargo size on Ran and energy requirements for nuclear protein import.
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J Cell Biol 2002 Oct; 159(1)55-67.
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Dynamics of leptomycin B-sensitive nucleocytoplasmic flux of parathyroid hormone-related protein.
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Traffic 2001 Nov; 2(11)812-9.
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Identification of nuclear import and export signals within the structure of the zinc finger protein TIS11.
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Biochem Biophys Res Commun 2002 May; 293(4)1242-7.
Score: 0.410
RNA export mediated by tap involves NXT1-dependent interactions with the nuclear pore complex.
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J Biol Chem 2001 Nov; 276(48)44953-62.
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Nup50, a nucleoplasmically oriented nucleoporin with a role in nuclear protein export.
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Mol Cell Biol 2000 Aug; 20(15)5619-30.
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Nuclear transport of H1 histones meets the criteria of a nuclear localization signal-mediated process.
M Kurz ... W Albig
J Cell Biochem 1997 Mar; 64(4)573-8.
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PHAX, a mediator of U snRNA nuclear export whose activity is regulated by phosphorylation.
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Cell 2000 Apr; 101(2)187-98.
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Dominant-negative mutants of importin-beta block multiple pathways of import and export through the nuclear pore complex.
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EMBO J 1997 Mar; 16(6)1153-63.
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Nuclear targeting and cell cycle regulatory function of human BARD1.
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Mechanisms of progesterone receptor export from nuclei: role of nuclear localization signal, nuclear export signal, and ran guanosine triphosphate.
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Mol Endocrinol 1998 Nov; 12(11)1684-95.
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The molecular mechanisms of messenger RNA nuclear export.
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Isoform-specific differences in rapid nucleocytoplasmic shuttling cause distinct subcellular distributions of 14-3-3 sigma and 14-3-3 zeta.
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J Cell Sci 2004 Mar; 117(Pt 8)1411-20.
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Subcellular localization of CrmA: identification of a novel leucine-rich nuclear export signal conserved in anti-apoptotic serpins.
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Biochem J 2003 Jul; 373(Pt 1)251-9.
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The Saccharomyces cerevisiae cyclin Clb2p is targeted to multiple subcellular locations by cis- and trans-acting determinants.
J K Hood ... P A Silver
J Cell Sci 2001 Feb; 114(Pt 3)589-97.
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The bipartite nuclear localization sequence of Rpn2 is required for nuclear import of proteasomal base complexes via karyopherin alphabeta and proteasome functions.
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J Biol Chem 2004 Sep; 279(36)37751-62.
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Nuclear import and the evolution of a multifunctional RNA-binding protein.
J S Rosenblum ... G Blobel
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Exportin 7 defines a novel general nuclear export pathway.
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Truncated form of importin alpha identified in breast cancer cell inhibits nuclear import of p53.
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J Biol Chem 2000 Jul; 275(30)23139-45.
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The nucleoporin Nup153 is required for nuclear pore basket formation, nuclear pore complex anchoring and import of a subset of nuclear proteins.
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The nuclear pore complex: structure, function, and dynamics.
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A nuclear export signal in Kap95p is required for both recycling the import factor and interaction with the nucleoporin GLFG repeat regions of Nup116p and Nup100p.
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A novel in vivo assay reveals inhibition of ribosomal nuclear export in ran-cycle and nucleoporin mutants.
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Exportin-5-mediated nuclear export of eukaryotic elongation factor 1A and tRNA.
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Inhibition of nuclear protein import by a monoclonal antibody against a novel class of nuclear pore proteins.
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Exp Cell Res 2005 Feb; 303(1)89-100.
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Nuclear import of mPER3 in Xenopus oocytes and HeLa cells requires complex formation with mPER1.
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Nuclear import of protein kinase C occurs by a mechanism distinct from the mechanism used by proteins with a classical nuclear localization signal.
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Nuclear export of mRNA.
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