FRISC: The Faculty Research Interests Science Comparator

David Corey, Ph.D.
Associate Professor of Pharmacology and Biochemistry
Molecular Biophysics
Biological Chemistry
Office: (214) 648-5096
Building: Y, Room: 4.206B
Email: corey@chop.swmed.edu
Home Page: Corey Lab Home Page

New This Month | New This Year | Abstract | Selected Publications | FRISC Statistics Results - FULL MEDLINE:

Cellular delivery of peptide nucleic acids and inhibition of human telomerase.
S E Hamilton ... D R Corey
Chem Biol 1999 Jun; 6(6)343-51.

Score: 0.704
Peptide nucleic acids: expanding the scope of nucleic acid recognition.
D R Corey
Trends Biotechnol 1997 Jun; 15(6)224-9.

Score: 0.616
Synthesis, analysis, purification, and intracellular delivery of peptide nucleic acids.
D A Braasch ... D R Corey
Methods 2001 Feb; 23(2)97-107.

Score: 0.615
Inhibition of gene expression inside cells by peptide nucleic acids: effect of mRNA target sequence, mismatched bases, and PNA length.
D F Doyle ... D R Corey
Biochemistry 2001 Jan; 40(1)53-64.

Score: 0.613
Liver cell specific targeting of peptide nucleic acid oligomers.
X Zhang ... D R Corey
Bioorg Med Chem Lett 2001 May; 11(10)1269-72.

Score: 0.598
The peptide nucleic acids (PNAs): a new generation of probes for genetic and cytogenetic analyses.
Petra Paulasova ... Franck Pellestor
Ann Genet 2004 Oct-Dec; 47(4)349-58.

Score: 0.589
The peptide nucleic acids (PNAs), powerful tools for molecular genetics and cytogenetics.
Franck Pellestor ... Petra Paulasova
Eur J Hum Genet 2004 Sep; 12(9)694-700.

Score: 0.588
The peptide nucleic acids (PNAs): introduction to a new class of probes for chromosomal investigation.
Franck Pellestor ... Petra Paulasova
Chromosoma 2004 Jun; 112(8)375-80.

Score: 0.579
Enhancement of strand invasion by oligonucleotides through manipulation of backbone charge.
S V Smulevitch ... D R Corey
Nat Biotechnol 1996 Dec; 14(13)1700-4.

Score: 0.561
Peptide nucleic acids and their potential applications in biotechnology.
O Buchardt ... P E Nielsen
Trends Biotechnol 1993 Sep; 11(9)384-6.

Score: 0.552
Strand invasion by mixed base PNAs and a PNA-peptide chimera.
X Zhang ... D R Corey
Nucleic Acids Res 2000 Sep; 28(17)3332-8.

Score: 0.550
Calcium liberates PNAs from endosomes.
David R Corey
Chem Biol 2005 Aug; 12(8)864-5.

Score: 0.550
Peptide nucleic acid conjugates: synthesis, properties and applications.
Zhanna V Zhilina ... Scot W Ebbinghaus
Curr Top Med Chem 2005 ; 5(12)1119-31.

Score: 0.548
Telomerase as a possible target for anticancer therapy.
C Autexier
Chem Biol 1999 Nov; 6(11)R299-303.

Score: 0.544
Delivery of antisense peptide nucleic acids (PNAs) to the cytosol by disulphide conjugation to a lipophilic cation.
Aleksandra Filipovska ... Michael P Murphy
FEBS Lett 2004 Jan; 556(1-3)180-6.

Score: 0.540
[The peptide nucleic acids (PNAs): "high-tech" probes for genetic and molecular cytogenetic investigations]
Franck Pellestor ... Samir Hamamah
Med Sci (Paris) 2005 Aug-Sep; 21(8-9)753-8.

Score: 0.526
Are PNAs a match for the BBB?
Martina Habeck
Drug Discov Today 2003 May; 8(9)377-8.

Score: 0.515
Failed to fetch article title! Article may not be available.
Score: 0.515
The use of peptide nucleic acids for in situ identification of human chromosomes.
Franck Pellestor ... Samir Hamamah
J Histochem Cytochem 2005 Mar; 53(3)395-400.

Score: 0.513
Inhibition of human telomerase activity by peptide nucleic acids.
J C Norton ... D R Corey
Nat Biotechnol 1996 May; 14(5)615-9.

Score: 0.512
(S,S)-trans-cyclopentane-constrained peptide nucleic acids. a general backbone modification that improves binding affinity and sequence specificity.
Jonathan K Pokorski ... Daniel H Appella
J Am Chem Soc 2004 Nov; 126(46)15067-73.

Score: 0.509
Recognition of chromosomal DNA by PNAs.
Kunihiro Kaihatsu ... David R Corey
Chem Biol 2004 Jun; 11(6)749-58.

Score: 0.507
Peptide nucleic acid delivery to human mitochondria.
P F Chinnery ... R N Lightowlers
Gene Ther 1999 Dec; 6(12)1919-28.

Score: 0.504
Efficient and isoform-selective inhibition of cellular gene expression by peptide nucleic acids.
Yinghui Liu ... David R Corey
Biochemistry 2004 Feb; 43(7)1921-7.

Score: 0.494
Extending recognition by peptide nucleic acids (PNAs): binding to duplex DNA and inhibition of transcription by tail-clamp PNA-peptide conjugates.
Kunihiro Kaihatsu ... David R Corey
Biochemistry 2003 Dec; 42(47)13996-4003.

Score: 0.493
Double duplex invasion by peptide nucleic acid: a general principle for sequence-specific targeting of double-stranded DNA.
J Lohse ... P E Nielsen
Proc Natl Acad Sci U S A 1999 Oct; 96(21)11804-8.

Score: 0.490
Peptide-nucleic acids (PNAs): a tool for the development of gene expression modifiers.
R Gambari
Curr Pharm Des 2001 Nov; 7(17)1839-62.

Score: 0.486
Insights into peptide nucleic acid (PNA) structural features: the crystal structure of a D-lysine-based chiral PNA-DNA duplex.
Valeria Menchise ... Carlo Pedone
Proc Natl Acad Sci U S A 2003 Oct; 100(21)12021-6.

Score: 0.486
A theoretical analysis of specificity of nucleic acid interactions with oligonucleotides and peptide nucleic acids (PNAs).
A Lomakin ... M D Frank-Kamenetskii
J Mol Biol 1998 Feb; 276(1)57-70.

Score: 0.484
Intracellular uptake and inhibition of gene expression by PNAs and PNA-peptide conjugates.
Kunihiro Kaihatsu ... David R Corey
Biochemistry 2004 Nov; 43(45)14340-7.

Score: 0.478
Inhibition of human telomerase by 2'-O-methyl-RNA.
A E Pitts ... D R Corey
Proc Natl Acad Sci U S A 1998 Sep; 95(20)11549-54.

Score: 0.471
Telomerase inhibition by peptide nucleic acids reverses 'immortality' of transformed human cells.
M A Shammas ... R J Shmookler Reis
Oncogene 1999 Nov; 18(46)6191-200.

Score: 0.469
Peptide nucleic acid-targeted mutagenesis of a chromosomal gene in mouse cells.
A F Faruqi ... P M Glazer
Proc Natl Acad Sci U S A 1998 Feb; 95(4)1398-403.

Score: 0.466
Strand invasion by DNA-peptide conjugates and peptide nucleic acids.
T Ishihara ... D R Corey
Nucleic Acids Symp Ser 1999 ; (42)141-2.

Score: 0.461
Peptide nucleic acids (PNAs), a chemical overview.
Andrea Porcheddu ... Giampaolo Giacomelli
Curr Med Chem 2005 ; 12(22)2561-99.

Score: 0.461
The peptide nucleic acids, efficient tools for molecular diagnosis (Review).
Franck Pellestor ... Petra Paulasova
Int J Mol Med 2004 Apr; 13(4)521-5.

Score: 0.458
Specific gene blockade shows that peptide nucleic acids readily enter neuronal cells in vivo.
B M Tyler ... E Richelson
FEBS Lett 1998 Jan; 421(3)280-4.

Score: 0.455
Peptide nucleic acids specifically cause antigene effects in vivo by systemic injection.
Beth M McMahon ... Elliott Richelson
Life Sci 2002 Jun; 71(3)325-37.

Score: 0.454
Antisense properties of duplex- and triplex-forming PNAs.
H Knudsen ... P E Nielsen
Nucleic Acids Res 1996 Feb; 24(3)494-500.

Score: 0.451
Peptide nucleic acids (PNA) and PNA-DNA chimeras: from high binding affinity towards biological function.
E Uhlmann
Biol Chem 1998 Aug-Sep; 379(8-9)1045-52.

Score: 0.438
Peptide nucleic acid (PNA) antisense effects in Escherichia coli.
L Good ... P E Nielsen
Curr Issues Mol Biol 1999 ; 1(1-2)111-6.

Score: 0.438
Nanocrystals modified with peptide nucleic acids (PNAs) for selective self-assembly and DNA detection.
Raj Chakrabarti ... Alexander M Klibanov
J Am Chem Soc 2003 Oct; 125(41)12531-40.

Score: 0.437
Comparison of novel delivery systems for antisense peptide nucleic acids.
Laura Chiarantini ... Luisa Tondelli
J Control Release 2005 Dec; 109(1-3)24-36.

Score: 0.436
Targeting peptide nucleic acid-protein conjugates to structural features within duplex DNA.
J C Norton ... D R Corey
Bioorg Med Chem 1995 Apr; 3(4)437-45.

Score: 0.429
An experimental and theoretical study of the gas-phase decomposition of monoprotonated peptide nucleic acids.
J W Flora ... D C Muddiman
J Am Soc Mass Spectrom 2000 Jul; 11(7)615-25.

Score: 0.429
Cyclohexanyl peptide nucleic acids (chPNAs) for preferential RNA binding: effective tuning of dihedral angle beta in PNAs for DNA/RNA discrimination.
T Govindaraju ... Krishna N Ganesh
J Org Chem 2006 Jan; 71(1)14-21.

Score: 0.427
Peptide nucleic acids (PNAs): potential antisense and anti-gene agents.
P E Nielsen ... O Buchardt
Anticancer Drug Des 1993 Feb; 8(1)53-63.

Score: 0.424
The PNAS way back then.
S Mac Lane
Proc Natl Acad Sci U S A 1997 Jun; 94(12)5983-5.

Score: 0.421
PNAs breach the blood-brain barrier?
M J During ... C G Janson
Nat Biotechnol 1999 Aug; 17(8)753-4.

Score: 0.421
The alpha-helical peptide nucleic acid concept: merger of peptide secondary structure and codified nucleic acid recognition.
Yumei Huang ... Philip Garner
J Am Chem Soc 2004 Apr; 126(14)4626-40.

Score: 0.415
Biological activity and delivery of peptide nucleic acids (PNA)-DNA chimeras for transcription factor decoy (TFD) pharmacotherapy.
Roberto Gambari
Curr Med Chem 2004 May; 11(10)1253-63.

Score: 0.414
Defining the peptide nucleic acids (PNA) length requirement for PNA binding-induced transcription and gene expression.
G Wang ... X Xu
J Mol Biol 2001 Nov; 313(5)933-40.

Score: 0.413
Recognition of chromosomal DNA in human cells by peptide nucleic acids and small duplex RNAs.
David R Corey
Ann N Y Acad Sci 2005 Nov; 1058()16-25.

Score: 0.413
Peptide nucleic acid-DNA decoy chimeras targeting NF-kappaB transcription factors: Induction of apoptosis in human primary osteoclasts.
Letizia Penolazzi ... Roberto Gambari
Int J Mol Med 2004 Aug; 14(2)145-52.

Score: 0.407
Inhibition of telomerase activity by a cell-penetrating peptide nucleic acid construct in human melanoma cells.
R Villa ... N Zaffaroni
FEBS Lett 2000 May; 473(2)241-8.

Score: 0.405
Crystallization and preliminary X-ray analysis of a PNA-DNA complex.
J S Kastrup ... H Rasmussen
FEBS Lett 1995 Apr; 363(1-2)115-7.

Score: 0.403
Bridging PNAs can bind preferentially to a deleted mitochondrial DNA template but replication by mitochondrial DNA polymerase gamma in vitro is not impaired.
Alistair McGregor ... Robert N Lightowlers
Biochim Biophys Acta 2003 Oct; 1629(1-3)73-83.

Score: 0.402
Inhibition of translation and bacterial growth by peptide nucleic acid targeted to ribosomal RNA.
L Good ... P E Nielsen
Proc Natl Acad Sci U S A 1998 Mar; 95(5)2073-6.

Score: 0.402
Intracellular inhibition of hepatitis C virus (HCV) internal ribosomal entry site (IRES)-dependent translation by peptide nucleic acids (PNAs) and locked nucleic acids (LNAs).
Christopher J Nulf ... David Corey
Nucleic Acids Res 2004 ; 32(13)3792-8.

Score: 0.402
Synthetic developments towards PNA-peptide conjugates.
Martijn C de Koning ... Mark Overhand
Curr Opin Chem Biol 2003 Dec; 7(6)734-40.

Score: 0.401
Gene sensors based on peptide nucleic acid (PNA) probes: relationship between sensor sensitivity and probe/target duplex stability.
Hiroshi Aoki ... Hiroaki Tao
Analyst 2005 Nov; 130(11)1478-82.

Score: 0.399
Synthesis and properties of peptide nucleic acids containing a psoralen unit.
A Okamoto ... I Saito
Org Lett 2001 Mar; 3(6)925-7.

Score: 0.397
Specific versus nonspecific binding of cationic PNAs to duplex DNA.
Ayome Abibi ... Maxim D Frank-Kamenetskii
Biophys J 2004 May; 86(5)3070-8.

Score: 0.396
End invasion of peptide nucleic acids (PNAs) with mixed-base composition into linear DNA duplexes.
Irina V Smolina ... Maxim D Frank-Kamenetskii
Nucleic Acids Res 2005 ; 33(17)e146.

Score: 0.396
Combined triplex/duplex invasion of double-stranded DNA by "tail-clamp" peptide nucleic acid.
Thomas Bentin ... Peter E Nielsen
Biochemistry 2003 Dec; 42(47)13987-95.

Score: 0.394
Enhanced recognition of cystic fibrosis W1282X DNA point mutation by chiral peptide nucleic acid probes by a surface plasmon resonance biosensor.
Roberto Corradini ... Roberto Gambari
J Mol Recognit 2004 Jan-Feb; 17(1)76-84.

Score: 0.393
Peptide nucleic acids targeted to the amyloid precursor protein.
Beth M McMahon ... Elliott Richelson
J Mol Neurosci 2003 ; 20(3)261-5.

Score: 0.392
PNAS reviewing procedures.
I B Dawid ... F R Zwanzig
Science 1989 Mar; 243(4897)1419.

Score: 0.390
PNAS to joint PubMed Central--on condition.
E Marshall
Science 1999 Oct; 286(5440)655-6.

Score: 0.390
Prediction of retention times of peptide nucleic acids during reversed-phase high-performance liquid chromatography.
R Hoffmann ... L Otvos
J Chromatogr A 1998 Jul; 814(1-2)111-9.

Score: 0.389
Short pyrimidine stretches containing mixed base PNAs are versatile tools to induce translation elongation arrest and truncated protein synthesis.
Catherine Sénamaud-Beaufort ... Tula Ester Saison-Behmoaras
Oligonucleotides 2003 ; 13(6)465-78.

Score: 0.386
Duesberg's PNAS paper.
P Duesberg
Science 1989 Mar; 243(4895)1125.

Score: 0.386
PD-loop: a complex of duplex DNA with an oligonucleotide.
N O Bukanov ... M D Frank-Kamenetskii
Proc Natl Acad Sci U S A 1998 May; 95(10)5516-20.

Score: 0.386
Modular nucleic acid surrogates. Solid phase synthesis of alpha-helical peptide nucleic acids (alpha PNAs).
P Garner ... X Zhang
Org Lett 1999 Aug; 1(3)403-5.

Score: 0.385
Peptide nucleic acid characterization by MALDI-TOF mass spectrometry.
J M Butler ... J Girard
Anal Chem 1996 Sep; 68(18)3283-7.

Score: 0.383
Identification and characterization of high affinity antisense PNAs for the human unr (upstream of N-ras) mRNA which is uniquely overexpressed in MCF-7 breast cancer cells.
Huafeng Fang ... John-Stephen Taylor
Nucleic Acids Res 2005 ; 33(21)6700-11.

Score: 0.374
Protein/oligonucleotide conjugates as a cell specific PNA carrier.
K Obara ... A Maruyama
Nucleic Acids Res Suppl 2001 ; (1)217-8.

Score: 0.374
Recognition and strand displacement of DNA oligonucleotides by peptide nucleic acids (PNAs). High-performance ion-exchange chromatographic analysis.
E Lesignoli ... R Marchelli
J Chromatogr A 2001 Jul; 922(1-2)177-85.

Score: 0.373
Information transfer from DNA to peptide nucleic acids by template-directed syntheses.
J G Schmidt ... L E Orgel
Nucleic Acids Res 1997 Dec; 25(23)4792-6.

Score: 0.373
Information transfer from peptide nucleic acids to RNA by template-directed syntheses.
J G Schmidt ... L E Orgel
Nucleic Acids Res 1997 Dec; 25(23)4797-802.

Score: 0.372
PNA-nitrogen mustard conjugates are effective suppressors of HER-2/neu and biological tools for recognition of PNA/DNA interactions.
Zhanna V Zhilina ... Scot W Ebbinghaus
Bioconjug Chem 2006 Jan-Feb; 17(1)214-22.

Score: 0.372
Intraperitoneal injection of antisense peptide nucleic acids targeted to the mu receptor decreases response to morphine and receptor protein levels in rat brain.
B M McMahon ... E Richelson
Brain Res 2001 Jun; 904(2)345-9.

Score: 0.368
PNA-related oligonucleotide mimics and their evaluation for nucleic acid hybridization studies and analysis.
V Efimov ... O Chakhmakhcheva
Nucleosides Nucleotides Nucleic Acids 2001 Apr-Jul; 20(4-7)419-28.

Score: 0.367
PNA microarrays for hybridisation of unlabelled DNA samples.
Ole Brandt ... Anette Jacob
Nucleic Acids Res 2003 Oct; 31(19)e119.

Score: 0.366
Liberalization of PNAS copyright policy: noncommercial use freely allowed.
Nicholas R Cozzarelli ... Diane M Sullenberger
Proc Natl Acad Sci U S A 2004 Aug; 101(34)12399.

Score: 0.365
AIDS paper raises red flag at PNAS.
W Booth
Science 1989 Feb; 243(4892)733.

Score: 0.364
Sequence-specific targeting of duplex DNA by peptide nucleic acids via triplex strand invasion.
V V Demidov ... M D Frank-Kamenetskii
Methods 2001 Feb; 23(2)108-22.

Score: 0.363
Sequence-specific inhibition of duck hepatitis B virus reverse transcription by peptide nucleic acids (PNA).
Magdalena Robaczewska ... Lucyna Cova
J Hepatol 2005 Feb; 42(2)180-7.

Score: 0.362
Evaluation of basic amphipathic peptides for cellular delivery of antisense peptide nucleic acids.
Martin A Maier ... Eric E Swayze
J Med Chem 2006 Apr; 49(8)2534-42.

Score: 0.362
Purine nucleoside analogues for the treatment of hematological malignancies: pharmacology and clinical applications.
T Robak ... P Smolewski
Curr Cancer Drug Targets 2005 Sep; 5(6)421-44.

Score: 0.361
Combination of a new generation of PNAs with a peptide-based carrier enables efficient targeting of cell cycle progression.
M C Morris ... G Divita
Gene Ther 2004 May; 11(9)757-64.

Score: 0.360
Liposomes as carriers for DNA-PNA hybrids.
C Nastruzzi ... C Mischiati
J Control Release 2000 Aug; 68(2)237-49.

Score: 0.360
Site-specific gene modification by PNAs conjugated to psoralen.
Ki-Hyun Kim ... Peter M Glazer
Biochemistry 2006 Jan; 45(1)314-23.

Score: 0.359
Bactericidal antisense effects of peptide-PNA conjugates.
L Good ... P E Nielsen
Nat Biotechnol 2001 Apr; 19(4)360-4.

Score: 0.358
Sequence-specific DNA strand cleavage by 111In-labeled peptide nucleic acids.
Yujian He ... Ronald D Neumann
Eur J Nucl Med Mol Imaging 2004 Jun; 31(6)837-45.

Score: 0.357
Peptide nucleic acids arrest the growth of gastric cancer cells SGC7901.
Kuan Wang ... Song-Bin Fu
Chin Med J (Engl) 2004 Apr; 117(4)566-70.

Score: 0.357
Negative selectivity and the evolution of protease cascades: the specificity of plasmin for peptide and protein substrates.
L S Hervio ... E L Madison
Chem Biol 2000 Jun; 7(6)443-53.

Score: 0.355
An assessment of the antisense properties of RNase H-competent and steric-blocking oligomers.
M A Bonham ... J E Bisi
Nucleic Acids Res 1995 Apr; 23(7)1197-203.

Score: 0.355
Single base pair mutation analysis by PNA directed PCR clamping.
H Orum ... C Stanley
Nucleic Acids Res 1993 Nov; 21(23)5332-6.

Score: 0.355
Synthesis and characterization of a peptide nucleic acid conjugated to a D-peptide analog of insulin-like growth factor 1 for increased cellular uptake.
S Basu ... E Wickstrom
Bioconjug Chem 1997 Jul-Aug; 8(4)481-8.

Score: 0.354
Peptide nucleic acid (PNA) amphiphiles: synthesis, self-assembly, and duplex stability.
James P Vernille ... James W Schneider
Bioconjug Chem 2004 Nov-Dec; 15(6)1314-21.

Score: 0.352
Anti-Ki-67 peptide nucleic acid affects the proliferation and apoptosis of human renal carcinoma cells in vitro.
Jun-Nian Zheng ... Jing-Yi Cao
Life Sci 2005 Mar; 76(16)1873-81.

Score: 0.350
Peptide nucleic acid (PNA) binding-mediated gene regulation.
Gan Wang ... Xiaoxin S Xu
Cell Res 2004 Apr; 14(2)111-6.

Score: 0.350
HPV18 E6 and E7 genes affect cell cycle, pRB and p53 of cervical tumor cells and represent prominent candidates for intervention by use peptide nucleic acids (PNAs).
Klaus Braun ... Jürgen Debus
Cancer Lett 2004 Jun; 209(1)37-49.

Score: 0.348
Antibiotic-free bacterial strain selection using antisense peptide nucleic acid.
Rikard Dryselius ... Liam Good
Biotechniques 2003 Nov; 35(5)1060-4.

Score: 0.348
High-performance liquid chromatography separation methods for the analysis of peptide nucleic acids.
Y Wei ... J E Girard
J Chromatogr A 1999 Dec; 864(1)49-57.

Score: 0.347
Cooperative strand invasion of supercoiled plasmid DNA by mixed linear PNA and PNA-peptide chimeras.
Karin E Lundin ... C I Edvard Smith
Biomol Eng 2004 Apr; 21(2)51-9.

Score: 0.347
Conjugates of PNA with naphthalene diimide derivatives having a broad range of DNA affinities.
Andriy A Mokhir ... Roland Kraemer
Bioconjug Chem 2003 Sep-Oct; 14(5)877-83.

Score: 0.346
Antisense peptide nucleic acids conjugated to somatostatin analogs and targeted at the n-myc oncogene display enhanced cytotoxity to human neuroblastoma IMR32 cells expressing somatostatin receptors.
Lichun Sun ... David H Coy
Peptides 2002 Sep; 23(9)1557-65.

Score: 0.345
PNAS policy on publication of sensitive material in the life sciences.
Nicholas R Cozzarelli
Proc Natl Acad Sci U S A 2003 Feb; 100(4)1463.

Score: 0.344
Identification of determinants for inhibitor binding within the RNA active site of human telomerase using PNA scanning.
S E Hamilton ... D R Corey
Biochemistry 1997 Sep; 36(39)11873-80.

Score: 0.344
Sequence-specific protection of duplex DNA against restriction and methylation enzymes by pseudocomplementary PNAs.
K I Izvolsky ... M D Frank-Kamenetskii
Biochemistry 2000 Sep; 39(35)10908-13.

Score: 0.341
Using peptide nucleic acids as gene-expression modifiers to reduce beta-amyloid levels.
Beth M McMahon ... Elliott Richelson
J Mol Neurosci 2002 Aug-Oct; 19(1-2)71-6.

Score: 0.341
Peptide-mediated cellular delivery of antisense oligonucleotides and their analogues.
Michael J Gait
Cell Mol Life Sci 2003 May; 60(5)844-53.

Score: 0.339
Peptide nucleic acids as antibacterial agents via the antisense principle.
P E Nielsen
Expert Opin Investig Drugs 2001 Feb; 10(2)331-41.

Score: 0.339
Targeting and regulation of the HER-2/neu oncogene promoter with bis-peptide nucleic acids.
Amy J Ziemba ... Scot W Ebbinghaus
Oligonucleotides 2005 ; 15(1)36-50.

Score: 0.339
Detection of genetically modified soybean using peptide nucleic acids (PNAs) and microarray technology.
Andrea Germini ... Gianluca De Bellis
J Agric Food Chem 2004 Jul; 52(14)4535-40.

Score: 0.338
Peptide nucleic acids as therapeutic agents.
P E Nielsen
Curr Opin Struct Biol 1999 Jun; 9(3)353-7.

Score: 0.337
Sequence specificity of alternating hydroyprolyl/phosphono peptide nucleic acids against zebrafish embryo mRNAs.
E Wickstrom ... S A Farber
J Drug Target 2004 Jul; 12(6)363-72.

Score: 0.336
Characterization of antisense binding properties of peptide nucleic acids by capillary gel electrophoresis.
D J Rose
Anal Chem 1993 Dec; 65(24)3545-9.

Score: 0.335
Phosphono peptide nucleic acids with a constrained hydroxyproline-based backbone.
Vladimir A Efimov ... Oksana G Chakhmakhcheva
Nucleosides Nucleotides Nucleic Acids 2003 May-Aug; 22(5-8)593-9.

Score: 0.334
Peptide nucleic acid (PNA) binding-mediated induction of human gamma-globin gene expression.
G Wang ... I Shokolenko
Nucleic Acids Res 1999 Jul; 27(13)2806-13.

Score: 0.333
Spermine conjugated peptide nucleic acids (spPNA): UV and fluorescence studies of PNA-DNA hybrids with improved stability.
B P Gangamani ... K N Ganesh
Biochem Biophys Res Commun 1997 Nov; 240(3)778-82.

Score: 0.332
RNA hairpin invasion and ribosome elongation arrest by mixed base PNA oligomer.
Nathalie Dias ... Tula Ester Saison-Behmoaras
J Mol Biol 2002 Jul; 320(3)489-501.

Score: 0.329
Hybridization of complementary and homologous peptide nucleic acid oligomers to a guanine quadruplex-forming RNA.
Violeta L Marin ... Bruce A Armitage
Biochemistry 2006 Feb; 45(6)1745-54.

Score: 0.329
Inhibiting transcription of chromosomal DNA with antigene peptide nucleic acids.
Bethany A Janowski ... David R Corey
Nat Chem Biol 2005 Sep; 1(4)210-5.

Score: 0.329
Directed gene modification via triple helix formation.
L Gorman ... P M Glazer
Curr Mol Med 2001 Jul; 1(3)391-9.

Score: 0.328
Strand-invasion of duplex DNA by peptide nucleic acid oligomers.
N J Peffer ... L E Babiss
Proc Natl Acad Sci U S A 1993 Nov; 90(22)10648-52.

Score: 0.327
Scientific publication. HHS Asks PNAS to pull bioterrorism paper.
Jon Cohen
Science 2005 Jun; 308(5727)1395.

Score: 0.326
New agents in chronic lymphocytic leukemia.
Tadeusz Robak
Curr Treat Options Oncol 2006 May; 7(3)200-12.

Score: 0.326
Computational procedures to explain the different biological activity of DNA/DNA, DNA/PNA and PNA/PNA hybrid molecules mimicking NF-kappaB binding sites.
M Saviano ... R Gambari
J Biomol Struct Dyn 2000 Dec; 18(3)353-62.

Score: 0.323
Antisense PNA effects in Escherichia coli are limited by the outer-membrane LPS layer.
L Good ... C Wahlestedt
Microbiology 2000 Oct; 146 ( Pt 10)()2665-70.

Score: 0.321
Synthesis and DNA binding properties of dioxime-peptide nucleic acids.
Andriy Mokhir ... Oleg A Varzatskii
Bioorg Med Chem Lett 2004 Jun; 14(11)2927-30.

Score: 0.321
Plant biology. NO-making enzyme no more: Cell, PNAS papers retracted.
John Travis
Science 2004 Nov; 306(5698)960.

Score: 0.319
Electron microscopy mapping of oligopurine tracts in duplex DNA by peptide nucleic acid targeting.
V V Demidov ... P E Nielsen
Nucleic Acids Res 1994 Dec; 22(24)5218-22.

Score: 0.319
Sequence-specific purification of nucleic acids by PNA-controlled hybrid selection.
H Orum ... T Koch
Biotechniques 1995 Sep; 19(3)472-80.

Score: 0.318
Therapy of chronic lymphocytic leukaemia with purine nucleoside analogues: facts and controversies.
Tadeusz Robak
Drugs Aging 2005 ; 22(12)983-1012.

Score: 0.317
Inhibition of gene expression by peptide nucleic acids in cultured cells.
Susanna Cogoi ... Luigi E Xodo
Nucleosides Nucleotides Nucleic Acids 2003 May-Aug; 22(5-8)1615-8.

Score: 0.317
Selective inhibition of inducible cyclo-oxygenase-2 expression by antisense peptide nucleic acids in intact murine macrophages.
Sonia Scarfì ... Gianluca Damonte
Biotechnol Appl Biochem 2003 Aug; 38(Pt 1)61-9.

Score: 0.315
Inhibition of Staphylococcus aureus gene expression and growth using antisense peptide nucleic acids.
Natalia Nekhotiaeva ... Liam Good
Mol Ther 2004 Oct; 10(4)652-9.

Score: 0.315
Aminoethylprolyl peptide nucleic acids (aepPNA): chiral PNA analogues that form highly stable DNA:aepPNA2 triplexes.
M D'Costa ... K N Ganesh
Org Lett 1999 Nov; 1(10)1513-6.

Score: 0.315
Peptide nucleic acid probe detection of mutations in Mycobacterium tuberculosis genes associated with drug resistance.
L E Bockstahler ... S L Morris
Biotechniques 2002 Mar; 32(3)508-10, 512, 514.

Score: 0.314
Improved nucleic acid triggered probe activation through the use of a 5-thiomethyluracil peptide nucleic acid building block.
Jianfeng Cai ... John Stephen Taylor
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