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FRISC: The Faculty Research Interests Science Comparator |
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Professor of Physiology
Biological Chemistry
Integrative Biology
Office: (214) 648-3308
FAX: (214) 648-4771
Email: gdemar@mednet.swmed.edu
The role of the proteasome in cellular protein degradation.
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Score: 0.634 | |
Role of the ubiquitin/proteasome system in regulated protein degradation in Saccharomyces cerevisiae.
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Score: 0.624 | |
Ubiquitin family proteins and their relationship to the proteasome: a structural perspective.
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Score: 0.615 | |
Localization to the proteasome is sufficient for degradation.
|
Score: 0.610 | |
Proteasomes.
|
Score: 0.603 | |
In vivo function of the proteasome in the ubiquitin pathway.
|
Score: 0.599 | |
Proteasome degradation: enter the substrate.
|
Score: 0.599 | |
The proteasome: a protein-destroying machine.
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Score: 0.596 | |
[The proteasome: destroy to live]
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Score: 0.584 | |
The proteasome.
|
Score: 0.583 | |
Deadly encounter: ubiquitin meets apoptosis.
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Score: 0.580 | |
Nature and role of proteasomes in maturation of fish oocytes.
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Score: 0.578 | |
ATP-dependent proteases degrade their substrates by processively unraveling them from the degradation signal.
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Score: 0.577 | |
Ubiquitin-independent proteolytic functions of the proteasome.
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Score: 0.571 | |
Protein regulation by monoubiquitin.
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Score: 0.571 | |
[Proteasomal degradation: from addressing of substrates to therapeutical perspectives]
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Score: 0.570 | |
Dis-assembly lines: the proteasome and related ATPase-assisted proteases.
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Score: 0.569 | |
Proteasome-associated proteins: regulation of a proteolytic machine.
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Score: 0.568 | |
Recombinant ATPases of the yeast 26S proteasome activate protein degradation by the 20S proteasome.
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Score: 0.568 | |
The 26S proteasome: ubiquitin-mediated proteolysis in the tunnel.
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Score: 0.565 | |
Ubiquitin-free routes into the proteasome.
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Score: 0.565 | |
A hitchhiker's guide to the proteasome.
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Score: 0.563 | |
Are expanded polyglutamine proteins a proteasome substrate?
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Score: 0.562 | |
Molecular shredders: how proteasomes fulfill their role.
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Score: 0.561 | |
A cryptic protease couples deubiquitination and degradation by the proteasome.
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Score: 0.560 | |
Targeting of substrates to the 26S proteasome.
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Score: 0.560 | |
Activity and regulation of the centrosome-associated proteasome.
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Score: 0.559 | |
Regulatory proteins of the proteasome.
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Score: 0.553 | |
Structure and functions of the 20S and 26S proteasomes.
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Score: 0.553 | |
[Proteasome and proteolysis]
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Score: 0.552 | |
The proteasome.
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Score: 0.550 | |
Proteasome-dependent, ubiquitin-independent degradation of the Rb family of tumor suppressors by the human cytomegalovirus pp71 protein.
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Score: 0.549 | |
Transferring substrates to the 26S proteasome.
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Score: 0.549 | |
20S proteasome prevents aggregation of heat-denatured proteins without PA700 regulatory subcomplex like a molecular chaperone.
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Score: 0.545 | |
Concurrent translocation of multiple polypeptide chains through the proteasomal degradation channel.
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Score: 0.545 | |
Ubiquitinylation is not an absolute requirement for degradation of c-Jun protein by the 26 S proteasome.
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Score: 0.544 | |
Proteasomes as drug targets.
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Score: 0.543 | |
The components of the proteasome system and their role in MHC class I antigen processing.
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Score: 0.543 | |
Mechanisms of protein degradation: an odyssey with ODC.
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Score: 0.542 | |
Proteasomes: a complex story.
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Score: 0.537 | |
Substrate access and processing by the 20S proteasome core particle.
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Score: 0.534 | |
Endoproteolytic activity of the proteasome.
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Score: 0.534 | |
Proteasome and transcription: a destroyer goes into construction.
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Score: 0.534 | |
Ubiquitin-dependent protein degradation: a cellular perspective.
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Score: 0.534 | |
Structural and functional analysis of the six regulatory particle triple-A ATPase subunits from the Arabidopsis 26S proteasome.
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Score: 0.531 | |
Proteasome inhibitors: valuable new tools for cell biologists.
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Score: 0.531 | |
Mobilizing the proteolytic machine: cell biological roles of proteasome activators and inhibitors.
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Score: 0.530 | |
Mechanism and function of deubiquitinating enzymes.
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Score: 0.530 | |
Proteolysis in plants: mechanisms and functions.
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Score: 0.528 | |
Proteasome assembly: biting the hand.
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Score: 0.528 | |
Ataxin-3 interactions with rad23 and valosin-containing protein and its associations with ubiquitin chains and the proteasome are consistent with a role in ubiquitin-mediated proteolysis.
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Score: 0.528 | |
Eponemycin exerts its antitumor effect through the inhibition of proteasome function.
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Score: 0.526 | |
Purification of PA700, the 19S regulatory complex of the 26S proteasome.
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Score: 0.526 | |
Getting in and out of the proteasome.
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Score: 0.523 | |
The hPLIC proteins may provide a link between the ubiquitination machinery and the proteasome.
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Score: 0.520 | |
The ubiquitin-proteasome pathway.
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Score: 0.519 | |
New insights into the mechanisms and importance of the proteasome in intracellular protein degradation.
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Score: 0.518 | |
The regulation of proteasome degradation by multi-ubiquitin chain binding proteins.
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Score: 0.518 | |
Ubiquitin-dependent protein degradation.
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Score: 0.517 | |
Ubiquitin-mediated proteolysis: biological regulation via destruction.
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Score: 0.514 | |
REGgamma: a shortcut to destruction.
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Score: 0.513 | |
Evidence for an interaction between ubiquitin-conjugating enzymes and the 26S proteasome.
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Score: 0.512 | |
Molecular biology of the proteasome.
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Score: 0.511 | |
Involvement of the proteasome in various degradative processes in mammalian cells.
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Score: 0.511 | |
The proteasome-dependent proteolytic system.
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Score: 0.509 | |
SCF and Cullin/Ring H2-based ubiquitin ligases.
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Score: 0.508 | |
Eukaryotic 20S proteasome catalytic subunit propeptides prevent active site inactivation by N-terminal acetylation and promote particle assembly.
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Score: 0.508 | |
The ubiquitin-proteasome proteolytic pathway: destruction for the sake of construction.
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Score: 0.508 | |
Sem1, the yeast ortholog of a human BRCA2-binding protein, is a component of the proteasome regulatory particle that enhances proteasome stability.
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Score: 0.508 | |
Ubiquitin conjugation is not required for the degradation of oxidized proteins by proteasome.
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Score: 0.507 | |
Investigating the importance of proteasome-interaction for Rad23 function.
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Score: 0.505 | |
Proteasome inhibitors as therapeutic agents: current and future strategies.
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Score: 0.504 | |
Proteasome involvement in the degradation of the G(q) family of Galpha subunits.
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Score: 0.504 | |
Ubiquitin proteasome pathway: implications and advances in cancer therapy.
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Score: 0.504 | |
Biogenesis, structure and function of the yeast 20S proteasome.
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Score: 0.504 | |
Natural substrates of the proteasome and their recognition by the ubiquitin system.
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Score: 0.504 | |
Regulation of proteolysis.
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Score: 0.503 | |
Does an inhibition of the ubiquitin/26S proteasome pathway of protein degradation underlie the pathogenesis of non-familial Alzheimer's disease?
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Score: 0.503 | |
Regulatory subunit interactions of the 26S proteasome, a complex problem.
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Score: 0.503 | |
The diverse roles of ubiquitin and the 26S proteasome in the life of plants.
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Score: 0.503 | |
The proteasome: structure, function, and role in the cell.
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Score: 0.501 | |
Catalytic activities of the 20 S proteasome, a multicatalytic proteinase complex.
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Score: 0.501 | |
The proteasome regulates the UV-induced activation of the AP-1-like transcription factor Gcn4.
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Score: 0.500 | |
Ubiquitin, proteasomes, and the regulation of intracellular protein degradation.
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Score: 0.500 | |
Role of Rpn11 metalloprotease in deubiquitination and degradation by the 26S proteasome.
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Score: 0.499 | |
Integral UBL domain proteins: a family of proteasome interacting proteins.
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Score: 0.495 | |
Degradation of ornithine decarboxylase by the mammalian and yeast 26S proteasome complexes requires all the components of the protease.
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Score: 0.495 | |
Natural products inhibiting the ubiquitin-proteasome proteolytic pathway, a target for drug development.
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Score: 0.494 | |
Protein dislocation from the ER requires polyubiquitination and the AAA-ATPase Cdc48.
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Score: 0.493 | |
Purification of the Arabidopsis 26 S proteasome: biochemical and molecular analyses revealed the presence of multiple isoforms.
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Score: 0.493 | |
Selective upregulation of the ubiquitin-proteasome proteolytic pathway proteins, proteasome zeta chain and isopeptidase T in fetal Down syndrome.
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Score: 0.492 | |
Impact of ageing on proteasome structure and function in human lymphocytes.
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Score: 0.491 | |
The proteasome: a proteolytic nanomachine of cell regulation and waste disposal.
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Score: 0.491 | |
Degradation of oxidized proteins in K562 human hematopoietic cells by proteasome.
|
Score: 0.490 | |
Caspase activation inhibits proteasome function during apoptosis.
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Score: 0.488 | |
Catalytic components of proteasomes and the regulation of proteinase activity.
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Score: 0.488 | |
Proteasomes: structure and biology.
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Score: 0.488 | |
Regulation of transcription factors by protein degradation.
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Score: 0.487 | |
Degradation of the yeast MAT alpha 2 transcriptional regulator is mediated by the proteasome.
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Score: 0.487 | |
The first characterization of a eubacterial proteasome: the 20S complex of Rhodococcus.
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Score: 0.487 | |
The yeast SEN3 gene encodes a regulatory subunit of the 26S proteasome complex required for ubiquitin-dependent protein degradation in vivo.
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Score: 0.486 | |
Degradation of methoxysuccinyl-phe-leu-phe-7-amido-4-trifluoromethyl coumarin (FLF) in cultured myotubes and HepG2 cells is proteasome- and calpain/calcium-dependent.
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Score: 0.486 | |
Stabilization signals: a novel regulatory mechanism in the ubiquitin/proteasome system.
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Score: 0.486 | |
Mechanisms of delivery of ubiquitylated proteins to the proteasome: new target for anti-cancer therapy?
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Score: 0.486 | |
Proteasomes: protein degradation machines of the cell.
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Score: 0.484 | |
New insights into proteasome function: from archaebacteria to drug development.
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Score: 0.484 | |
Ubiquitin and control of transcription.
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Score: 0.484 | |
Proteasome inhibition: a new strategy in cancer treatment.
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Score: 0.484 | |
Proteasome: a complex protease with a new fold and a distinct mechanism.
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Score: 0.484 | |
Impairment of proteasome structure and function in aging.
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Score: 0.483 | |
Apoptosis and the proteasome.
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Score: 0.483 | |
Checkpoints in ER-associated degradation: excuse me, which way to the proteasome?
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Score: 0.483 | |
Monitoring the ubiquitin/proteasome system in conformational diseases.
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Score: 0.483 | |
Feeding the machine: mechanisms of proteasome-catalyzed degradation of ubiquitinated proteins.
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Score: 0.482 | |
Proteasome inhibition in multiple myeloma: therapeutic implication.
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Score: 0.482 | |
Genomic association of the proteasome demonstrates overlapping gene regulatory activity with transcription factor substrates.
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Score: 0.482 | |
An unstructured initiation site is required for efficient proteasome-mediated degradation.
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Score: 0.478 | |
[Proteasomes. Complex proteases lead to a new understanding of cellular regulation through proteolysis]
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Score: 0.478 | |
Recognition of the polyubiquitin proteolytic signal.
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Score: 0.478 | |
The ubiquitin-proteasome pathway of intracellular proteolysis.
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Score: 0.477 | |
Physical association of ubiquitin ligases and the 26S proteasome.
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Score: 0.476 | |
Orchestra for assembly and fate of polyubiquitin chains.
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Score: 0.476 | |
Chaperone activities of the 26S and 20S proteasome.
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Score: 0.476 | |
Degradation of hypochlorite-damaged glucose-6-phosphate dehydrogenase by the 20S proteasome.
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Score: 0.476 | |
Role and function of the 26S proteasome in proliferation and apoptosis.
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Score: 0.475 | |
The proteasome and MHC class I antigen processing.
|
Score: 0.475 | |
Deubiquitination by proteasome is coordinated with substrate translocation for proteolysis in vivo.
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Score: 0.475 | |
Cooperation of molecular chaperones with the ubiquitin/proteasome system.
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Score: 0.475 | |
O-GlcNAc modification is an endogenous inhibitor of the proteasome.
|
Score: 0.475 | |
The proteasome: not just degrading anymore.
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Score: 0.474 | |
Cdc48-Ufd2-Rad23: the road less ubiquitinated?
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Score: 0.474 | |
Proteasome inhibitors as anti-cancer agents.
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Score: 0.474 | |
Ubiquitin-dependent signaling: the role of ubiquitination in the response of cells to their environment.
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Score: 0.474 | |
The proteasome in brain aging.
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Score: 0.473 | |
The proteasome.
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Score: 0.473 | |
[Intracellular proteolysis: signals of selective protein degradation]
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Score: 0.473 | |
Ubiquitin-proteasome-mediated local protein degradation and synaptic plasticity.
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Score: 0.472 | |
In vivo disassembly of free polyubiquitin chains by yeast Ubp14 modulates rates of protein degradation by the proteasome.
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Score: 0.472 | |
Analysis of Drosophila 26 S proteasome using RNA interference.
|
Score: 0.471 | |
The proteasome: a new target for novel drug therapies.
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Score: 0.471 | |
Highbrow proteasome in high-throughput technology.
|
Score: 0.470 | |
Subcellular localization, stoichiometry, and protein levels of 26 S proteasome subunits in yeast.
|
Score: 0.467 | |
Properties of 26S proteasome purified from rat skeletal muscles: comparison with those of 26S proteasome from the rat brain.
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Score: 0.466 | |
Assessment of proteasome activity in cell lysates and tissue homogenates using peptide substrates.
|
Score: 0.466 | |
Structural features of the 26 S proteasome complex.
|
Score: 0.466 | |
Mapping and structural dissection of human 20 S proteasome using proteomic approaches.
|
Score: 0.465 | |
The ultimate nanoscale mincer: assembly, structure and active sites of the 20S proteasome core.
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Score: 0.465 | |
Linkage between the proteasome pathway and neurodegenerative diseases and aging.
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Score: 0.465 | |
Targeting the ubiquitin-proteasome pathway in breast cancer.
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Score: 0.465 | |
Ubiquitin-mediated degradation of cellular proteins: why destruction is essential for construction, and how it got from the test tube to the patient's bed.
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Score: 0.464 | |
Degradation of ornithine decarboxylase by the 26S proteasome.
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Score: 0.464 | |
Proteasomal defense of oxidative protein modifications.
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Score: 0.463 | |
Keepers at the final gates: regulatory complexes and gating of the proteasome channel.
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Score: 0.463 | |
The regulatory particle of the Saccharomyces cerevisiae proteasome.
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Score: 0.463 | |
Proteasome inhibition in glyoxal-treated fibroblasts and resistance of glycated glucose-6-phosphate dehydrogenase to 20 S proteasome degradation in vitro.
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Score: 0.463 | |
The ubiquitin 26S proteasome proteolytic pathway.
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Score: 0.462 | |
The Doa4 deubiquitinating enzyme is required for ubiquitin homeostasis in yeast.
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Score: 0.462 | |
The ubiquitin-mediated proteolytic pathway: enzymology and mechanisms of recognition of the proteolytic substrates.
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Score: 0.461 | |
[A new therapy with bortezomib, an oncologic medicinal product of the year 2004]
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Score: 0.461 | |
Purification, crystallization, and X-ray analysis of the yeast 20S proteasome.
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Score: 0.461 | |
Proteasome inhibitors and antigen presentation.
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Score: 0.461 | |
Proteasomes of the yeast S. cerevisiae: genes, structure and functions.
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Score: 0.461 | |
Rings, chains and ladders: ubiquitin goes to work in the neuron.
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Score: 0.461 | |
Ornithine decarboxylase is degraded by the 26S proteasome without ubiquitination.
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Score: 0.461 | |
Discrimination between ubiquitin-dependent and ubiquitin-independent proteolytic pathways by the 26S proteasome subunit 5a.
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Score: 0.459 | |
Insulin-induced insulin receptor substrate-1 degradation is mediated by the proteasome degradation pathway.
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Score: 0.459 | |
The ubiquitin-proteasome pathway and its role in cancer.
|
Score: 0.458 | |
Cooperation of a ubiquitin domain protein and an E3 ubiquitin ligase during chaperone/proteasome coupling.
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Score: 0.456 | |
Proteins interacting with the 26S proteasome.
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Score: 0.456 | |
cDNA cloning of p42, a shared subunit of two proteasome regulatory proteins, reveals a novel member of the AAA protein family.
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Score: 0.455 | |
ATP-Dependent inactivation and sequestration of ornithine decarboxylase by the 26S proteasome are prerequisites for degradation.
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Score: 0.455 | |
The 26S proteasome: subunits and functions.
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Score: 0.455 | |
Conformational remodeling of proteasomal substrates by PA700, the 19 S regulatory complex of the 26 S proteasome.
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Score: 0.455 | |
[Update on . . . the proteasome inhibitor PS341]
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Score: 0.454 | |
Identification, purification, and characterization of a protein activator (PA28) of the 20 S proteasome (macropain).
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Score: 0.454 | |
Antigen presentation by MHC class I and its regulation by interferon gamma.
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Score: 0.454 | |
Structural studies of the interaction between ubiquitin family proteins and proteasome subunit S5a.
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Score: 0.453 | |
LMP2 knock-out mice have reduced proteasome activities and increased levels of oxidatively damaged proteins.
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Score: 0.453 | |
Regulating the 26S proteasome.
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Score: 0.453 | |
Ubiquitylation of BAG-1 suggests a novel regulatory mechanism during the sorting of chaperone substrates to the proteasome.
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Score: 0.453 | |
Involvement of the 20S proteasome in the degradation of ornithine decarboxylase.
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Score: 0.451 | |
Assaying degradation and deubiquitination of a ubiquitinated substrate by purified 26S proteasomes.
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Score: 0.451 | |
The proteasome in cancer biology and treatment.
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Score: 0.451 | |
ATP-dependent proteases in prokaryotic and eukaryotic cells.
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Score: 0.451 | |
Editing of ubiquitin conjugates by an isopeptidase in the 26S proteasome.
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Score: 0.450 | |
Recent advances in the identification and development of 20S proteasome inhibitors.
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Score: 0.450 | |
Studies on the yeast proteasome uncover its basic structural features and multiple in vivo functions.
|
Score: 0.449 | |
Rad23 and Rpn10 serve as alternative ubiquitin receptors for the proteasome.
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Score: 0.449 | |
Go outside and see the proteasome. Protein degradation.
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Score: 0.449 | |
Autocatalytic subunit processing couples active site formation in the 20S proteasome to completion of assembly.
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Score: 0.449 | |
Role of 26S proteasome and HRD genes in the degradation of 3-hydroxy-3-methylglutaryl-CoA reductase, an integral endoplasmic reticulum membrane protein.
|
Score: 0.449 | |
A proteolytic system that compensates for loss of proteasome function.
|
Score: 0.449 | |
The Png1-Rad23 complex regulates glycoprotein turnover.
|
Score: 0.448 | |
Regulation of apoptosis by the ubiquitin and proteasome pathway.
|
Score: 0.448 | |
The ubiquitin-mediated proteolytic pathway: mode of action and clinical implications.
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Score: 0.448 | |
Felix Hoppe-Seyler Lecture 2000. The ubiquitin system and the N-end rule pathway.
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Score: 0.447 | |
Purification and properties of the 26S proteasome from the rat brain: evidence for its degradation of myelin basic protein in a ubiquitin-dependent manner.
|
Score: 0.447 | |
ATPase and ubiquitin-binding proteins of the yeast proteasome.
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Score: 0.447 | |
Delivery of ubiquitinated substrates to protein-unfolding machines.
|
Score: 0.445 | |
TRAF2: a double-edged sword?
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Score: 0.445 | |
Sem1p is a novel subunit of the 26 S proteasome from Saccharomyces cerevisiae.
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Score: 0.445 | |
Metabolism of the polyubiquitin degradation signal: structure, mechanism, and role of isopeptidase T.
|
Score: 0.444 | |
The 19S regulatory complex of the proteasome functions independently of proteolysis in nucleotide excision repair.
|
Score: 0.444 | |
The ubiquitin system.
|
Score: 0.444 | |
Sequestosome 1/p62 is a polyubiquitin chain binding protein involved in ubiquitin proteasome degradation.
|
Score: 0.444 | |
The proteasome: a novel therapeutic target in haematopoietic malignancy.
|
Score: 0.443 | |
Quaternary structure of the ATPase complex of human 26S proteasomes determined by chemical cross-linking.
|
Score: 0.443 | |
Selective degradation of oxidized calmodulin by the 20 S proteasome.
|
Score: 0.442 | |
Sarcomeric myosin heavy chain is degraded by the proteasome.
|
Score: 0.442 | |
Inhibition of the 26 S proteasome by polyubiquitin chains synthesized to have defined lengths.
|
Score: 0.442 | |
Redox modulation of cellular metabolism through targeted degradation of signaling proteins by the proteasome.
|
Score: 0.442 | |
The ubiquitin-mediated proteolytic pathway: mechanisms of action and cellular physiology.
|
Score: 0.441 | |
Caretaker or undertaker? The role of the proteasome in aging.
|
Score: 0.441 | |
The proteasome: a central regulator of inflammation and macrophage function.
|
Score: 0.441 | |
Retro hydrazino-azapeptoids as peptidomimetics of proteasome inhibitors.
|
Score: 0.440 | |
Lactacystin, an inhibitor of the proteasome, blocks the degradation of a mutant precursor of glycosylphosphatidylinositol-linked protein in a pre-Golgi compartment.
|
Score: 0.439 | |
The ubiquitin-mediated proteolytic pathway: mechanisms of recognition of the proteolytic substrate and involvement in the degradation of native cellular proteins.
|
Score: 0.439 | |
Ubiquitin-dependent proteolysis: its role in human diseases and the design of therapeutic strategies.
|
Score: 0.438 | |
SCF ubiquitin protein ligases and phosphorylation-dependent proteolysis.
|
Score: 0.438 | |
Identification and characterization of a Drosophila proteasome regulatory network.
|
Score: 0.438 | |
Inefficient degradation of truncated polyglutamine proteins by the proteasome.
|
Score: 0.438 | |
The 26S proteasome degrades mouse and yeast ornithine decarboxylase in yeast cells.
|
Score: 0.438 | |
Regulation of apoptosis: the ubiquitous way.
|
Score: 0.438 | |
Control of gene expression by proteolysis.
|
Score: 0.438 | |
Proteasome inhibitors: from research tools to drug candidates.
|
Score: 0.437 | |
ATP hydrolysis-dependent disassembly of the 26S proteasome is part of the catalytic cycle.
|
Score: 0.437 | |
Urban renewal in the nucleus: is protein turnover by proteasomes absolutely required for nuclear receptor-regulated transcription?
|
Score: 0.437 | |
The de-ubiquitinating enzyme Unp interacts with the retinoblastoma protein.
|
Score: 0.437 | |
Proteasomes in apoptosis: villains or guardians?
|
Score: 0.436 | |
Rpn4 is a physiological substrate of the Ubr2 ubiquitin ligase.
|
Score: 0.436 | |
Multiple associated proteins regulate proteasome structure and function.
|
Score: 0.436 | |
Molecular structure of 20S and 26S proteasomes.
|
Score: 0.436 | |
Purification and characterization of a protein inhibitor of the 20S proteasome (macropain).
|
Score: 0.436 | |
Emerging roles of ubiquitin in transcription regulation.
|
Score: 0.435 | |
Molecular regulation of muscle cachexia: it may be more than the proteasome.
|
Score: 0.435 | |
The HEAT repeat protein Blm10 regulates the yeast proteasome by capping the core particle.
|
Score: 0.435 | |
The proteasome, a new target for cancer therapy.
|
Score: 0.435 | |
Saccharomyces cerevisiae Ub-conjugating enzyme Ubc4 binds the proteasome in the presence of translationally damaged proteins.
|
Score: 0.435 | |
Proteasome structures affected by ionizing radiation.
|
Score: 0.434 | |
Translocation-arrested apolipoprotein B evades proteasome degradation via a sterol-sensitive block in ubiquitin conjugation.
|
Score: 0.434 | |
Molecular pathways that modify tumor radiation response.
|
Score: 0.434 | |
Ubiquitination and deubiquitination: targeting of proteins for degradation by the proteasome.
|
Score: 0.434 | |
Adenylate cyclase regulation via proteasome-mediated modulation of Galphas levels.
|
Score: 0.434 | |
Ubiquitin, E6-AP, and their role in p53 inactivation.
|
Score: 0.434 | |
Protein degradation by the proteasome and its implications in aging.
|
Score: 0.434 | |
Homologues of 26S proteasome subunits are regulators of transcription and translation.
|
Score: 0.433 | |
Purification and characterization of the 26S proteasome complex catalyzing ATP-dependent breakdown of ubiquitin-ligated proteins from rat liver.
|
Score: 0.433 | |
Degradation of Id proteins by the ubiquitin-proteasome pathway.
|
Score: 0.433 | |
Are there multiple proteolytic pathways contributing to c-Fos, c-Jun and p53 protein degradation in vivo?
|
Score: 0.433 | |
Post-translationally modified S12, absent in transformed breast epithelial cells, is not associated with the 26S proteasome and is induced by proteasome inhibitor.
|
Score: 0.432 | |
Monitoring of ubiquitin-dependent proteolysis with green fluorescent protein substrates.
|
Score: 0.432 | |
Amyloid beta-protein inhibits ubiquitin-dependent protein degradation in vitro.
|
Score: 0.432 | |
Recognition of misfolding proteins by PA700, the regulatory subcomplex of the 26 S proteasome.
|
Score: 0.432 | |
Molecular organization of the 20S proteasome gene family from Arabidopsis thaliana.
|
Score: 0.432 | |
Selective degradation of oxidatively modified protein substrates by the proteasome.
|
Score: 0.432 | |
Clastosome: a subtype of nuclear body enriched in 19S and 20S proteasomes, ubiquitin, and protein substrates of proteasome.
|
Score: 0.431 | |
Proteases and protein degradation in Escherichia coli.
|
Score: 0.431 | |
Inhibitors of the eukaryotic 20S proteasome core particle: a structural approach.
|
Score: 0.431 | |
The 26S proteasome: a molecular machine designed for controlled proteolysis.
|
Score: 0.431 | |
The ubiquitin-proteasome pathway is required for the function of the viral VP16 transcriptional activation domain.
|
Score: 0.431 | |
Role of the proteasome in membrane extraction of a short-lived ER-transmembrane protein.
|
Score: 0.431 | |
The proteasome and protein degradation in yeast.
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