FRISC: The Faculty Research Interests Science Comparator

William T. Garrard, Ph.D.
Professor of Molecular Biology
Biological Chemistry
Genetics and
Development
Immunology
Integrative Biology
Office: (214) 648-1924
FAX: (214) 648-1909
Email: william.garrard@utsouthwestern.edu
Home Page: http://www.swmed.edu/home_pages/garrardlab/

New This Month | New This Year | Abstract | Selected Publications | FRISC Statistics Results - FULL MEDLINE:

Immunoglobulin kappa light chain gene promoter and enhancer are not responsible for B-cell restricted gene rearrangement.
M Goodhardt ... F Rougeon
Nucleic Acids Res 1989 Sep; 17(18)7403-15.
Score: 0.577
Rearrangement and expression of rabbit immunoglobulin kappa light chain gene in transgenic mice.
M Goodhardt ... F Rougeon
Proc Natl Acad Sci U S A 1987 Jun; 84(12)4229-33.
Score: 0.525
High-level rearrangement and transcription of yeast artificial chromosome-based mouse Ig kappa transgenes containing distal regions of the contig.
S Li ... W T Garrard
J Immunol 2000 Jan; 164(2)812-24.
Score: 0.525
Enhancer sequences located 3' of the mouse immunoglobulin lambda locus specify high-level expression of an immunoglobulin lambda gene in B cells of transgenic mice.
S Eccles ... F Grosveld
New Biol 1990 Sep; 2(9)801-11.
Score: 0.506
High expression of cloned immunoglobulin kappa gene in transgenic mice is restricted to B lymphocytes.
U Storb ... R L Brinster
Nature 1984 Jul 19-25; 310(5974)238-41.
Score: 0.503
Variegated transcriptional activation of the immunoglobulin kappa locus in pre-b cells contributes to the allelic exclusion of light-chain expression.
Hong-Erh Liang ... Mark S Schlissel
Cell 2004 Jul; 118(1)19-29.
Score: 0.495
Allelic exclusion and control of endogenous immunoglobulin gene rearrangement in kappa transgenic mice.
K A Ritchie ... U Storb
Nature 1984 Dec 6-12; 312(5994)517-20.
Score: 0.481
Immunoglobulin kappa gene enhancers synergistically activate gene expression but independently determine chromatin structure.
V C Blasquez ... W T Garrard
J Biol Chem 1992 Nov; 267(33)23888-93.
Score: 0.478
Chromatin structural analyses of the mouse Igkappa gene locus reveal new hypersensitive sites specifying a transcriptional silencer and enhancer.
Zhi-Mei Liu ... William T Garrard
J Biol Chem 2002 Sep; 277(36)32640-9.
Score: 0.476
Regulation of the immunoglobulin gene transcription.
G Lefranc ... M P Lefranc
Biochimie 1990 Jan; 72(1)7-17.
Score: 0.470
A developmentally modulated chromatin structure at the mouse immunoglobulin kappa 3' enhancer.
M C Roque ... V C Blasquez
Mol Cell Biol 1996 Jun; 16(6)3138-55.
Score: 0.465
Nucleosomes and regulation of gene expression. Structure of the HIV-1 5'LTR.
P Widłak ... W T Garrard
Acta Biochim Pol 1998 ; 45(1)209-19.
Score: 0.462
B lineage-restricted rearrangement of a human Ig kappa transgene.
P Cavelier ... M Goodhardt
Eur J Immunol 1997 Jul; 27(7)1626-31.
Score: 0.460
Chromosomal loop anchorage sites appear to be evolutionarily conserved.
P N Cockerill ... W T Garrard
FEBS Lett 1986 Aug; 204(1)5-7.
Score: 0.455
Yeast artificial chromosome contigs reveal that distal variable-region genes reside at least 3 megabases from the joining regions in the murine immunoglobulin kappa locus.
J B George ... W T Garrard
Proc Natl Acad Sci U S A 1995 Dec; 92(26)12421-5.
Score: 0.454
DNase I hypersensitive sites flank the mouse class II major histocompatibility complex during B cell development.
S Carson
Nucleic Acids Res 1991 Sep; 19(18)5007-14.
Score: 0.452
Immunoglobulin lambda gene rearrangement can precede kappa gene rearrangement.
J Berg ... M Wabl
Dev Immunol 1990 ; 1(1)53-7.
Score: 0.451
Aberrant recombination events in B cell lines derived from a kappa-deficient human.
J Stavnezer ... B J Zegers
Nucleic Acids Res 1985 May; 13(10)3495-514.
Score: 0.450
Transposed human immunoglobulin V kappa gene regions carry clusters of conserved sequence elements.
E Lötscher ... H G Zachau
Gene 1988 Sep; 69(2)225-36.
Score: 0.448
Rabbit immunoglobulin kappa genes: structure of a germline b4 allotype J-C locus and evidence for several b4-related sequences in the rabbit genome.
L Emorine ... E E Max
Proc Natl Acad Sci U S A 1983 Sep; 80(18)5709-13.
Score: 0.440
Structure of a nuclease-sensitive region inside the immunoglobin kappa gene: evidence for a role in gene regulation.
T G Parslow ... D K Granner
Nucleic Acids Res 1983 Jul; 11(14)4775-92.
Score: 0.439
Searching for non-V kappa transcripts from the human immunoglobulin kappa locus.
A Lautner-Rieske ... H G Zachau
Gene 1995 Jul; 159(2)199-202.
Score: 0.438
B cell development in mice that lack one or both immunoglobulin kappa light chain genes.
J Chen ... D Huszar
EMBO J 1993 Mar; 12(3)821-30.
Score: 0.438
The immunoglobulin kappa locus-or-what has been learned from looking closely at one-tenth of a percent of the human genome.
H G Zachau
Gene 1993 Dec; 135(1-2)167-73.
Score: 0.438
Human immunoglobulin variable region genes--DNA sequences of two V kappa genes and a pseudogene.
D L Bentley ... T H Rabbits
Nature 1980 Dec; 288(5792)730-3.
Score: 0.437
Methylation status and DNase I sensitivity of immunoglobulin genes: changes associated with rearrangement.
E L Mather ... R P Perry
Proc Natl Acad Sci U S A 1983 Aug; 80(15)4689-93.
Score: 0.435
Stepwise activation of the mouse acetylcholine receptor delta- and gamma-subunit genes in clonal cell lines.
C M Crowder ... J P Merlie
Mol Cell Biol 1988 Dec; 8(12)5257-67.
Score: 0.434
Regulation of activation and recombination of the murine Igkappa locus.
Mark S Schlissel
Immunol Rev 2004 Aug; 200()215-23.
Score: 0.434
Regulation of the chicken lysozyme locus in transgenic mice.
C Bonifer ... A E Sippel
Crit Rev Eukaryot Gene Expr 1996 ; 6(2-3)285-97.
Score: 0.432
The immunoglobulin kappa gene families of human and mouse: a cottage industry approach.
H G Zachau
Biol Chem 2000 Sep-Oct; 381(9-10)951-4.
Score: 0.432
Different joining region J elements of the murine kappa immunoglobulin light chain locus are used at markedly different frequencies.
D L Wood ... C Coleclough
Proc Natl Acad Sci U S A 1984 Aug; 81(15)4756-60.
Score: 0.432
The enhancer of the immunoglobulin heavy chain locus is flanked by presumptive chromosomal loop anchorage elements.
P N Cockerill ... W T Garrard
J Biol Chem 1987 Apr; 262(11)5394-7.
Score: 0.430
Functional analysis of DNase-I hypersensitive sites at the mouse porphobilinogen deaminase gene locus. Different requirements for position-independent expression from its two promoters.
C Porcher ... B Grandchamp
J Biol Chem 1995 Jul; 270(29)17368-74.
Score: 0.428
The role of immunoglobulin kappa elements in c-myc activation.
K Hörtnagel ... A Polack
Oncogene 1995 Apr; 10(7)1393-401.
Score: 0.428
Aberrant rearrangement of the kappa light-chain locus involving the heavy-chain locus and chromosome 15 in a mouse plasmacytoma.
B G VanNess ... F Ruddle
Nature 1983 Feb; 301(5899)425-7.
Score: 0.427
Chromosomal loop anchorage of the kappa immunoglobulin gene occurs next to the enhancer in a region containing topoisomerase II sites.
P N Cockerill ... W T Garrard
Cell 1986 Jan; 44(2)273-82.
Score: 0.426
A targeted deletion of a region upstream from the Jkappa cluster impairs kappa chain rearrangement in cis in mice and in the 103/bcl2 cell line.
L Cocea ... C A Reynaud
J Exp Med 1999 May; 189(9)1443-50.
Score: 0.426
Activation of immunoglobulin kappa gene rearrangement correlates with induction of germline kappa gene transcription.
M S Schlissel ... D Baltimore
Cell 1989 Sep; 58(5)1001-7.
Score: 0.425
Transcription termination and chromatin structure of the active immunoglobulin kappa gene locus.
M Xu ... W T Garrard
J Biol Chem 1986 Mar; 261(8)3838-45.
Score: 0.424
Elements regulating somatic hypermutation of an immunoglobulin kappa gene: critical role for the intron enhancer/matrix attachment region.
A G Betz ... M S Neuberger
Cell 1994 Apr; 77(2)239-48.
Score: 0.423
A nuclear factor that binds to a conserved sequence motif in transcriptional control elements of immunoglobulin genes.
H Singh ... P A Sharp
Nature 1986 Jan 9-15; 319(6049)154-8.
Score: 0.423
Sequences containing the second-intron enhancer are essential for transcription of the human apolipoprotein B gene in the livers of transgenic mice.
A R Brooks ... B Levy-Wilson
Mol Cell Biol 1994 Apr; 14(4)2243-56.
Score: 0.423
Biochemical and functional analyses of chromatin changes at the TCR-beta gene locus during CD4-CD8- to CD4+CD8+ thymocyte differentiation.
S Chattopadhyay ... J Chen
J Immunol 1998 Feb; 160(3)1256-67.
Score: 0.421
The immunoglobulin lambda light chain enhancer consists of three modules which synergize in activation of transcription.
H Asenbauer ... H G Klobeck
Eur J Immunol 1999 Feb; 29(2)713-24.
Score: 0.421
Sequences at the somatic recombination sites of immunoglobulin light-chain genes.
H Sakano ... S Tonegawa
Nature 1979 Jul; 280(5720)288-94.
Score: 0.421
A lymphocyte-specific enhancer in the mouse immunoglobulin kappa gene.
D Picard ... W Schaffner
Nature 1984 Jan 5-11; 307(5946)80-2.
Score: 0.420
The kinetics of V-J joining throughout 3.5 megabases of the mouse Ig kappa locus fit a constrained diffusion model of nuclear organization.
Shuyu Li ... William T Garrard
FEBS Lett 2003 Feb; 536(1-3)125-9.
Score: 0.420
Biallelic germline transcription at the kappa immunoglobulin locus.
Nandita Singh ... Andrew Chess
J Exp Med 2003 Mar; 197(6)743-50.
Score: 0.420
Comparison of mouse and rabbit Ei kappa enhancers indicates that different elements within the enhancer may mediate activation of transcription and recombination.
I Coquilleau ... M Goodhardt
J Immunol 2000 Jan; 164(2)795-804.
Score: 0.419
A large upstream region is not necessary for gene expression or hypersensitive site formation at the mouse beta -globin locus.
C M Farrell ... G Felsenfeld
Proc Natl Acad Sci U S A 2000 Dec; 97(26)14554-9.
Score: 0.419
A novel enhancer in the immunoglobulin lambda locus is duplicated and functionally independent of NF kappa B.
J Hagman ... U Storb
Genes Dev 1990 Jun; 4(6)978-92.
Score: 0.419
The intronic immunoglobulin kappa gene enhancer acts independently on rearrangement and on transcription.
S Kallenbach ... F Rougeon
Eur J Immunol 1993 Aug; 23(8)1917-21.
Score: 0.417
Human antibodies from transgenic mice.
N Lonberg ... D Huszar
Int Rev Immunol 1995 ; 13(1)65-93.
Score: 0.416
The developmental activation of the chicken lysozyme locus in transgenic mice requires the interaction of a subset of enhancer elements with the promoter.
M C Huber ... C Bonifer
Nucleic Acids Res 1997 Aug; 25(15)2992-3000.
Score: 0.414
Cell-type preference of immunoglobulin kappa and lambda gene promoters.
D Picard ... W Schaffner
EMBO J 1985 Nov; 4(11)2831-8.
Score: 0.413
Expression of a microinjected immunoglobulin gene in the spleen of transgenic mice.
R L Brinster ... U Storb
Nature 1983 Nov 24-30; 306(5941)332-6.
Score: 0.411
Structural analysis of mouse rDNA: coincidence between nuclease hypersensitive sites, DNA curvature and regulatory elements in the intergenic spacer.
G Längst ... I Grummt
Nucleic Acids Res 1997 Feb; 25(3)511-7.
Score: 0.410
Preferential rearrangement of the immunoglobulin kappa chain joining region J kappa 1 and J kappa 2 segments in mouse spleen DNA.
M Nishi ... T Honjo
Proc Natl Acad Sci U S A 1985 Oct; 82(19)6399-403.
Score: 0.409
Silencing of the expression of the immunoglobulin kappa gene in non-B cells.
J W Pierce ... D Baltimore
Mol Cell Biol 1991 Mar; 11(3)1431-7.
Score: 0.408
Rearrangement of genetic information may produce immunoglobulin diversity.
M Weigert ... L Hood
Nature 1978 Dec 21-28; 276(5690)785-90.
Score: 0.407
Correct in vivo splicing of the mouse immunoglobulin kappa light-chain pre-mRNA is dependent on 5' splice-site position even in the absence of transcription.
D H Kedes ... J A Steitz
Genes Dev 1988 Nov; 2(11)1448-59.
Score: 0.407
Genomic position effects lead to an inefficient reorganization of nucleosomes in the 5'-regulatory region of the chicken lysozyme locus in transgenic mice.
M C Huber ... C Bonifer
Nucleic Acids Res 1996 Apr; 24(8)1443-52.
Score: 0.406
Cell-type-specific transcription of an immunoglobulin kappa light chain gene in vitro.
J Mizushima-Sugano ... R G Roeder
Proc Natl Acad Sci U S A 1986 Nov; 83(22)8511-5.
Score: 0.406
Position-independent, high-level expression of the human beta-globin gene in transgenic mice.
F Grosveld ... G Kollias
Cell 1987 Dec; 51(6)975-85.
Score: 0.405
The mouse immunoglobulin kappa locus contains about 140 variable gene segments.
T Kirschbaum ... H G Zachau
Eur J Immunol 1996 Jul; 26(7)1613-20.
Score: 0.405
Deletion of the immunoglobulin kappa chain intron enhancer abolishes kappa chain gene rearrangement in cis but not lambda chain gene rearrangement in trans.
S Takeda ... K Rajewsky
EMBO J 1993 Jun; 12(6)2329-36.
Score: 0.404
In vivo occupancy of the kappa light chain enhancers in primary pro- and pre-B cells: a model for kappa locus activation.
A L Shaffer ... M S Schlissel
Immunity 1997 Feb; 6(2)131-43.
Score: 0.404
Immunoglobulin kappa gene expression after stable integration. II. Role of the intronic MAR and enhancer in transgenic mice.
M Xu ... W T Garrard
J Biol Chem 1989 Dec; 264(35)21190-5.
Score: 0.404
Immunoglobulin gene transcription is activated by downstream sequence elements.
C Queen ... D Baltimore
Cell 1983 Jul; 33(3)741-8.
Score: 0.404
Cloning and characterization of the mouse glucokinase gene locus and identification of distal liver-specific DNase I hypersensitive sites.
C Postic ... M A Magnuson
Genomics 1995 Oct; 29(3)740-50.
Score: 0.403
Locus control region elements HS2 and HS3 in combination with chromatin boundaries confer high-level expression of a human beta-globin transgene in a centromeric region.
Sung-Hae Lee Kang ... Jörg Bungert
Genes Cells 2004 Nov; 9(11)1043-53.
Score: 0.403
Two structurally distinct kappa B sequence motifs cooperatively control LPS-induced KC gene transcription in mouse macrophages.
Y Ohmori ... T A Hamilton
J Immunol 1995 Oct; 155(7)3593-600.
Score: 0.402
Lack of somatic mutation in a kappa light chain transgene.
M J Sharpe ... C Milstein
Eur J Immunol 1990 Jun; 20(6)1379-85.
Score: 0.402
The importance of the 3'-enhancer region in immunoglobulin kappa gene expression.
K B Meyer ... M S Neuberger
Nucleic Acids Res 1990 Oct; 18(19)5609-15.
Score: 0.402
Germ-line transmission and developmental regulation of a 150-kb yeast artificial chromosome containing the human beta-globin locus in transgenic mice.
K M Gaensler ... Y W Kan
Proc Natl Acad Sci U S A 1993 Dec; 90(23)11381-5.
Score: 0.402
A yeast artificial chromosome contig spanning the mouse immunoglobulin kappa light chain locus.
I W Schupp ... T Boehm
Immunogenetics 1997 ; 45(3)180-7.
Score: 0.401
Essential role of NF-E2 in remodeling of chromatin structure and transcriptional activation of the epsilon-globin gene in vivo by 5' hypersensitive site 2 of the beta-globin locus control region.
Q H Gong ... A Dean
Mol Cell Biol 1996 Nov; 16(11)6055-64.
Score: 0.400
Clustered and interspersed gene families in the mouse immunoglobulin kappa locus.
I Zocher ... H G Zachau
Eur J Immunol 1995 Dec; 25(12)3326-31.
Score: 0.400
Locus control regions and epigenetic chromatin modifiers.
R Festenstein ... D Kioussis
Curr Opin Genet Dev 2000 Apr; 10(2)199-203.
Score: 0.400
Nuclear factors bind to regulatory regions of the mouse kappa immunoglobulin gene.
R Hromas ... B Van Ness
Nucleic Acids Res 1986 Jun; 14(12)4837-48.
Score: 0.400
Diversity in the rabbit immunoglobulin kappa chain variable regions is amplified by nucleotide deletions and insertions at the V-J junction.
O Heidmann ... F Rougeon
Cell 1983 Oct; 34(3)767-77.
Score: 0.400
Individual LCR hypersensitive sites cooperate to generate an open chromatin domain spanning the human beta-globin locus.
G Li ... J Bungert
Genes Cells 1998 Jul; 3(7)415-29.
Score: 0.400
The mouse M-lysozyme gene domain: identification of myeloid and differentiation specific DNasel hypersensitive sites and of a 3'-cis acting regulatory element.
B Möllers ... R Renkawitz
Nucleic Acids Res 1992 Apr; 20(8)1917-24.
Score: 0.400
Lipopolysaccharide-induced transcription of the kappa immunoglobulin locus occurs on both alleles and is independent of methylation status.
K J Nelson ... R P Perry
Nucleic Acids Res 1984 Feb; 12(4)1911-23.
Score: 0.399
Identification of two enhancer elements downstream of the human c-myc gene.
J Mautner ... A Polack
Nucleic Acids Res 1995 Jan; 23(1)72-80.
Score: 0.398
Negative regulation of immunoglobulin kappa light-chain gene transcription by a short sequence homologous to the murine B1 repetitive element.
K Saksela ... D Baltimore
Mol Cell Biol 1993 Jun; 13(6)3698-705.
Score: 0.398
Differential accessibility at the kappa chain locus plays a role in allelic exclusion.
Maya Goldmit ... Yehudit Bergman
EMBO J 2002 Oct; 21(19)5255-61.
Score: 0.397
Dynamic chromatin: the regulatory domain organization of eukaryotic gene loci.
C Bonifer ... A E Sippel
J Cell Biochem 1991 Oct; 47(2)99-108.
Score: 0.397
Megabase inversions in the human genome as physiological events.
G M Weichhold ... H G Zachau
Nature 1990 Sep; 347(6288)90-2.
Score: 0.397
Uncoupling gene activity from chromatin structure: promoter mutations can inactivate transcription of the yeast HSP82 gene without eliminating nucleosome-free regions.
M S Lee ... W T Garrard
Proc Natl Acad Sci U S A 1992 Oct; 89(19)9166-70.
Score: 0.396
The human immunoglobulin kappa locus. Characterization of the duplicated A regions.
A Lautner-Rieske ... H G Zachau
Eur J Immunol 1992 Apr; 22(4)1023-9.
Score: 0.396
Contribution of promoter to tissue-specific expression of the mouse immunoglobulin kappa gene.
T V Gopal ... A W Nienhuis
Science 1985 Sep; 229(4718)1102-4.
Score: 0.396
Differences in the nuclease sensitivity between the two alleles of the immunoglobulin kappa light chain genes in mouse liver and myeloma nuclei.
W O Weischet ... H G Zachau
Nucleic Acids Res 1982 Jun; 10(12)3627-45.
Score: 0.395
DNase I-hypersensitive sites in the chromatin of immunoglobulin kappa light chain genes.
S Y Chung ... J Wooley
Proc Natl Acad Sci U S A 1983 May; 80(9)2427-31.
Score: 0.395
Deletions of kappa chain constant region genes in mouse lambda chain-producing B cells involve intrachromosomal DNA recombinations similar to V-J joining.
M W Moore ... E Selsing
Proc Natl Acad Sci U S A 1985 Sep; 82(18)6211-5.
Score: 0.392
A targeted kappa immunoglobulin gene containing a deletion of the nuclear matrix association region exhibits spontaneous hyper-recombination in pre-B cells.
M A Hale ... W T Garrard
Mol Immunol 1998 Jul; 35(10)609-20.
Score: 0.392
Immunoglobulin gene rearrangement in B cell deficient mice generated by targeted deletion of the JH locus.
J Chen ... D Huszar
Int Immunol 1993 Jun; 5(6)647-56.
Score: 0.392
Immunoglobulin gene 'remnant' DNA--implications for antibody gene recombination.
E Selsing ... U Storb
Nucleic Acids Res 1984 May; 12(10)4229-46.
Score: 0.391
Locus control regions of mammalian beta-globin gene clusters: combining phylogenetic analyses and experimental results to gain functional insights.
R Hardison ... W Miller
Gene 1997 Dec; 205(1-2)73-94.
Score: 0.391
Somatic hypermutation of immunoglobulin kappa may depend on sequences 3' of C kappa and occurs on passenger transgenes.
M J Sharpe ... M S Neuberger
EMBO J 1991 Aug; 10(8)2139-45.
Score: 0.390
Somatic rearrangements forming active immunoglobulin mu genes in B and T lymphoid cell lines.
S Cory ... D J Kemp
Proc Natl Acad Sci U S A 1980 Aug; 77(8)4943-7.
Score: 0.390
Assembly and analysis of the mouse immunoglobulin kappa gene sequence.
Katherine M Brekke ... William T Garrard
Immunogenetics 2004 Oct; 56(7)490-505.
Score: 0.390
Distal regulatory elements from the mouse metallothionein locus stimulate gene expression in transgenic mice.
R D Palmiter ... R L Brinster
Mol Cell Biol 1993 Sep; 13(9)5266-75.
Score: 0.389
Chromatin structure and transcriptional regulation of the beta-globin locus.
Xiang Hui Fu ... Chih-Chuan Liang
Exp Cell Res 2002 Aug; 278(1)1-11.
Score: 0.388
Structure of the 5' ends of immunoglobulin genes: a novel conserved sequence.
T G Parslow ... D K Granner
Proc Natl Acad Sci U S A 1984 May; 81(9)2650-4.
Score: 0.388
Analysis of the structural integrity of YACs comprising human immunoglobulin genes in yeast and in embryonic stem cells.
M J Mendez ... D Garza
Genomics 1995 Mar; 26(2)294-307.
Score: 0.388
Enhancer-dependent expression of human kappa immunoglobulin genes introduced into mouse pre-B lymphocytes by electroporation.
H Potter ... P Leder
Proc Natl Acad Sci U S A 1984 Nov; 81(22)7161-5.
Score: 0.387
Interallelic and intergenic conversion events could induce differential evolution of the two rabbit immunoglobulin kappa light chain genes.
B Mariame ... F Rougeon
Nucleic Acids Res 1987 Aug; 15(15)6171-9.
Score: 0.387
Somatic DNA rearrangement generates functional rat immunoglobulin kappa chain genes: the J kappa gene cluster is longer in rat than in mouse.
A V Breiner ... I Schechter
Gene 1982 May; 18(2)165-74.
Score: 0.386
Creation of mice expressing human antibody light chains by introduction of a yeast artificial chromosome containing the core region of the human immunoglobulin kappa locus.
N P Davies ... M Brüggemann
Biotechnology (N Y) 1993 Aug; 11(8)911-4.
Score: 0.386
Expression, allelic exclusion and somatic mutation of mouse immunoglobulin kappa genes.
U Storb ... R Brinster
Immunol Rev 1986 Feb; 89()85-102.
Score: 0.386
Sequences of five potential recombination sites encoded close to an immunoglobulin kappa constant region gene.
E E Max ... P Leder
Proc Natl Acad Sci U S A 1979 Jul; 76(7)3450-4.
Score: 0.386
The immunoglobulin kappa locus contains a second, stronger B-cell-specific enhancer which is located downstream of the constant region.
K B Meyer ... M S Neuberger
EMBO J 1989 Jul; 8(7)1959-64.
Score: 0.386
Activation of V kappa gene rearrangement in pre-B cells follows the expression of membrane-bound immunoglobulin heavy chains.
M Reth ... F W Alt
EMBO J 1987 Nov; 6(11)3299-305.
Score: 0.385
Th2-specific chromatin remodeling and enhancer activity in the Th2 cytokine locus control region.
Patrick E Fields ... Richard A Flavell
Immunity 2004 Dec; 21(6)865-76.
Score: 0.385
Rearrangement-enhancing element upstream of the mouse immunoglobulin kappa chain J cluster.
L Ferradini ... J C Weill
Science 1996 Mar; 271(5254)1416-20.
Score: 0.385
The joining of V and J gene segments creates antibody diversity.
M Weigert ... L Hood
Nature 1980 Jan; 283(5746)497-9.
Score: 0.385
Multiple changes in chromatin structure precede the transcriptional activation of the human growth hormone locus in placental cells.
G Jiménez ... A Boronat
Mol Cell Endocrinol 1993 Oct; 96(1-2)53-60.
Score: 0.383
Changes in chromatin organization at the neutrophil elastase locus associated with myeloid cell differentiation.
E T Wong ... C B Gilks
Blood 1999 Dec; 94(11)3730-6.
Score: 0.382
The mouse immunoglobulin kappa light-chain genes are located in early- and late-replicating regions of chromosome 6.
K S Hatton ... C L Schildkraut
Mol Cell Biol 1990 Aug; 10(8)4314-23.
Score: 0.382
Dispersed human immunoglobulin kappa light-chain genes.
E Lötscher ... H G Zachau
Nature 1986 Apr 3-9; 320(6061)456-8.
Score: 0.382
Somatic mutation creates diversity in the major group of mouse immunoglobulin kappa light chains.
G Heinrich ... S Tonegawa
J Exp Med 1984 Feb; 159(2)417-35.
Score: 0.382
V(D)J recombination of immunoglobulin genes.
C Oka ... M Kawaichi
Adv Biophys 1995 ; 31()163-80.
Score: 0.382
The human immunoglobulin kappa locus. Characterization of the duplicated O regions.
W Pargent ... H G Zachau
Eur J Immunol 1991 Aug; 21(8)1821-7.
Score: 0.382
Chromatin structure of the murine c-myc locus: implications for the regulation of normal and chromosomally translocated genes.
P D Fahrlander ... K B Marcu
EMBO J 1985 Dec; 4(12)3195-202.
Score: 0.381
The 5' part of the mouse immunoglobulin kappa locus.
F Röschenthaler ... H G Zachau
Eur J Immunol 1999 Jul; 29(7)2065-71.
Score: 0.381
Correct transcription of an immunoglobulin kappa gene requires an upstream fragment containing conserved sequence elements.
F G Falkner ... H G Zachau
Nature 1984 Jul 5-11; 310(5972)71-4.
Score: 0.381
The J kappa proximal region of the human K locus contains three uncommon V kappa genes which are arranged in opposite transcriptional polarities.
W Lorenz ... H G Zachau
Mol Immunol 1988 May; 25(5)479-84.
Score: 0.381
Chromatin structure and functional analysis of the mouse HNF3alpha gene.
A G Lodmell ... K S Zaret
Gene 1998 Jul; 214(1-2)167-76.
Score: 0.381
Human lymphoma differentiation concepts correlate with in vitro action of immunoglobulin gene-specific transcription factors.
A E Kossakowska ... D P Bazett-Jones
Leukemia 1988 May; 2(5)290-5.
Score: 0.381
Tissue-specific DNase I hypersensitive sites in a foreign globin gene in transgenic mice.
G Radice ... F Costantini
Nucleic Acids Res 1986 Dec; 14(24)9765-80.
Score: 0.381
Structural polymorphism of V kappa 21 E and V kappa 21 D gene products in laboratory mice.
D Primi ... P A Cazenave
Eur J Immunol 1986 Mar; 16(3)292-6.
Score: 0.381
A targeted mutation at the T-cell receptor alpha/delta locus impairs T-cell development and reveals the presence of the nearby antiapoptosis gene Dad1.
N A Hong ... A Winoto
Mol Cell Biol 1997 Apr; 17(4)2151-7.
Score: 0.381
Electroporation of embryonic stem cells for generating transgenic mice and studying in vitro differentiation.
J S Mudgett ... T J Livelli
Methods Mol Biol 1995 ; 48()167-84.
Score: 0.380
Recruitment of transcription complexes to the beta-globin locus control region and transcription of hypersensitive site 3 prior to erythroid differentiation of murine embryonic stem cells.
Padraic P Levings ... Jörg Bungert
FEBS J 2006 Feb; 273(4)746-55.
Score: 0.380
Isotype exclusion and transgene down-regulation in immunoglobulin-lambda transgenic mice.
M S Neuberger ... M A Surani
Nature 1989 Mar; 338(6213)350-2.
Score: 0.379
A deletion of the human beta-globin locus activation region causes a major alteration in chromatin structure and replication across the entire beta-globin locus.
W C Forrester ... M Groudine
Genes Dev 1990 Oct; 4(10)1637-49.
Score: 0.379
Rearrangement of immunoglobulin kappa gene in a variant-type Burkitt lymphoma cell line, KOBK101, carrying a translocation between chromosomes 2 and 8.
M Fujino ... S Nakazawa
Jpn J Cancer Res 1986 Jan; 77(1)24-7.
Score: 0.378
Nuclease hypersensitive regions with adjacent positioned nucleosomes mark the gene boundaries of the PHO5/PHO3 locus in yeast.
A Almer ... W Hörz
EMBO J 1986 Oct; 5(10)2681-7.
Score: 0.378
The use of DNase I hypersensitivity site mapping to identify regulatory regions of the human cholinergic gene locus.
H Tanaka ... L B Hersh
J Neurochem 1998 May; 70(5)1799-808.
Score: 0.378
The Drosophila RBP-J kappa gene encodes the binding protein for the immunoglobulin J kappa recombination signal sequence.
T Furukawa ... T Honjo
J Biol Chem 1991 Dec; 266(34)23334-40.
Score: 0.378
Hormone-induced modifications of the chromatin structure surrounding upstream regulatory regions conserved between the mouse and rabbit whey acidic protein genes.
Benjamin Millot ... Eve Devinoy
Biochem J 2003 May; 372(Pt 1)41-52.
Score: 0.378
Light chain isotype regulation in the horse. Characterization of Ig kappa genes.
J E Ford ... D M Gibson
J Immunol 1994 Aug; 153(3)1099-111.
Score: 0.378
Development of B cells in scid mice with immunoglobulin transgenes: implications for the control of V(D)J recombination.
Y Chang ... M J Bosma
Immunity 1995 Jun; 2(6)607-16.
Score: 0.377
A conserved sequence in the immunoglobulin J kappa-C kappa intron: possible enhancer element.
L Emorine ... E E Max
Nature 1983 Aug 4-10; 304(5925)447-9.
Score: 0.377
Cloned human and mouse kappa immunoglobulin constant and J region genes conserve homology in functional segments.
P A Hieter ... P Leder
Cell 1980 Nov; 22(1 Pt 1)197-207.
Score: 0.377
Chromosomal position of rearranging gene segments influences allelic exclusion in transgenic mice.
T E Costa ... M C Nussenzweig
Proc Natl Acad Sci U S A 1992 Mar; 89(6)2205-8.
Score: 0.377
Role of the intronic elements in the endogenous immunoglobulin heavy chain locus. Either the matrix attachment regions or the core enhancer is sufficient to maintain expression.
E J Wiersma ... M J Shulman
J Biol Chem 1999 Feb; 274(8)4858-62.
Score: 0.377
Corepression of RelA and c-rel inhibits immunoglobulin kappa gene transcription and rearrangement in precursor B lymphocytes.
D C Scherer ... E M Oltz
Immunity 1996 Dec; 5(6)563-74.
Score: 0.377
Prerequisites for tissue specific and position independent expression of a gene locus in transgenic mice.
C Bonifer ... A E Sippel
J Mol Med 1996 Nov; 74(11)663-71.
Score: 0.376
Fine mapping of an immunoglobulin gene activator.
C Queen ... J Stafford
Mol Cell Biol 1984 Jun; 4(6)1042-9.
Score: 0.376
A novel type of aberrant recombination in immunoglobulin genes and its implications for V-J joining mechanism.
J Höchtl ... H G Zachau
Nature 1983 Mar 17-23; 302(5905)260-3.
Score: 0.376
Regulatory elements in the immunoglobulin kappa locus induce c-myc activation and the promoter shift in Burkitt's lymphoma cells.
A Polack ... K Hörtnagel
EMBO J 1993 Oct; 12(10)3913-20.
Score: 0.376
Cloning of the Ly-6A (Sca-1) gene locus and identification of a 3' distal fragment responsible for high-level gamma-interferon-induced expression in vitro.
X Ma ... E Dzierzak
Br J Haematol 2001 Sep; 114(3)724-30.
Score: 0.376
A potentially functional V kappa gene at a distance of 1.5 Mb from the immunoglobulin kappa locus.
C Huber ... H G Zachau
Genomics 1994 Jul; 22(1)213-5.
Score: 0.375
Activation of the weakly regulated PHO8 promoter in S. cerevisiae: chromatin transition and binding sites for the positive regulatory protein PHO4.
S Barbarić ... W Hörz
Nucleic Acids Res 1992 Mar; 20(5)1031-8.
Score: 0.375
How immunoglobulin V kappa genes rearrange.
M A Shapiro ... M Weigert
J Immunol 1987 Dec; 139(11)3834-9.
Score: 0.375
Double recombination of a single immunoglobulin kappa-chain allele: implications for the mechanism of rearrangement.
R M Feddersen ... B G Van Ness
Proc Natl Acad Sci U S A 1985 Jul; 82(14)4793-7.
Score: 0.374
NRF2, a member of the NFE2 family of transcription factors, is not essential for murine erythropoiesis, growth, and development.
K Chan ... Y W Kan
Proc Natl Acad Sci U S A 1996 Nov; 93(24)13943-8.
Score: 0.373
B lymphocytes may escape tolerance by revising their antigen receptors.
M Z Radic ... M Weigert
J Exp Med 1993 Apr; 177(4)1165-73.
Score: 0.373
Transgenic mice: a tool for the study of tissue-specific gene expression.
J Jami
Nouv Rev Fr Hematol 1988 ; 30(1-2)7-11.
Score: 0.373
Structure and expression of the mouse prealbumin gene.
S Wakasugi ... K Shimada
J Biochem (Tokyo) 1986 Jul; 100(1)49-58.
Score: 0.373
Dissection of the locus control function located on the chicken lysozyme gene domain in transgenic mice.
C Bonifer ... A E Sippel
Nucleic Acids Res 1994 Oct; 22(20)4202-10.
Score: 0.372
Corrective recombination of mouse immunoglobulin kappa alleles in Abelson murine leukemia virus-transformed pre-B cells.
R M Feddersen ... B G Van Ness
Mol Cell Biol 1990 Feb; 10(2)569-76.
Score: 0.372
Identification of a second inducible DNA-protein interaction in the kappa immunoglobulin enhancer.
K Nelms ... B Van Ness
Nucleic Acids Res 1990 Feb; 18(4)1037-43.
Score: 0.372
High-frequency loss of specific immunoglobulin production in hybridoma cell lines bearing a chromosomal immunoglobulin kappa gene modified by homologous recombination.
P Ng ... M D Baker
Somat Cell Mol Genet 1994 Mar; 20(2)107-19.
Score: 0.372
Pax-5 is essential for kappa sterile transcription during Ig kappa chain gene rearrangement.
Hiromu Sato ... Akira Kudo
J Immunol 2004 Apr; 172(8)4858-65.
Score: 0.372
A murine T cell receptor gene complex: isolation, structure and rearrangement.
M M Davis ... S M Hedrick
Immunol Rev 1984 Oct; 81()235-58.
Score: 0.371
The human V kappa locus. Characterization of extended immunoglobulin gene regions by cosmid cloning.
H D Pohlenz ... H G Zachau
J Mol Biol 1987 Jan; 193(2)241-53.
Score: 0.371
Transcription of mouse kappa chain genes: implications for allelic exclusion.
R P Perry ... M Weigert
Proc Natl Acad Sci U S A 1980 Apr; 77(4)1937-41.
Score: 0.371
The human immunoglobulin kappa locus: pseudogenes, unique and repetitive sequences.
K Schäble ... H G Zachau
Biol Chem Hoppe Seyler 1994 Mar; 375(3)189-99.
Score: 0.371
The chromatin structure of the human epsilon globin gene: nuclease hypersensitive sites correlate with multiple initiation sites of transcription.
J Zhu ... J Paul
Nucleic Acids Res 1984 Dec; 12(23)9191-204.
Score: 0.370
Modern evolution of a single-copy gene: the immunoglobulin C kappa locus in wild mice.
E Jouvin-Marche ... S Rudikoff
Mol Biol Evol 1988 Sep; 5(5)500-11.
Score: 0.370
Embryonic stem cell culture and gene targeting in transgenic mice.
H Baribault ... R Kemler
Mol Biol Med 1989 Dec; 6(6)481-92.
Score: 0.370
Role of positive and negative cis-regulatory elements in the transcriptional activation of the lysozyme locus in developing macrophages of transgenic mice.
U Jägle ... C Bonifer
J Biol Chem 1997 Feb; 272(9)5871-9.
Score: 0.370
Quantification of DNaseI-sensitivity by real-time PCR: quantitative analysis of DNaseI-hypersensitivity of the mouse beta-globin LCR.
M McArthur ... G Stamatoyannopoulos
J Mol Biol 2001 Oct; 313(1)27-34.
Score: 0.369
Positive elements in the laminin gamma 1 gene synergize to activate high level transcription during cellular differentiation.
H S Chang ... S L Phillips
Nucleic Acids Res 1996 Apr; 24(7)1360-8.
Score: 0.369
Regulation of the myeloid-cell-expressed human gp91-phox gene as studied by transfer of yeast artificial chromosome clones into embryonic stem cells: suppression of a variegated cellular pattern of expression requires a full complement of distant cis elements.
L L Lien ... S H Orkin
Mol Cell Biol 1997 Apr; 17(4)2279-90.
Score: 0.369
B-lymphocyte targeting of gene expression in transgenic mice with the immunoglobulin heavy-chain enhancer.
P Gerlinger ... B Wasylyk
Nucleic Acids Res 1986 Aug; 14(16)6565-77.
Score: 0.369
Mutation pattern of immunoglobulin transgenes is compatible with a model of somatic hypermutation in which targeting of the mutator is linked to the direction of DNA replication.
B Rogerson ... U Storb
EMBO J 1991 Dec; 10(13)4331-41.
Score: 0.369
Transcriptional activation and DNase I hypersensitive sites are associated with selective expression of the gastrin-releasing peptide gene.
S Markowitz ... J Battey
J Clin Invest 1988 Sep; 82(3)808-15.
Score: 0.368
Site-independent expression of the chicken beta A-globin gene in transgenic mice.
M Reitman ... G Felsenfeld
Nature 1990 Dec 20-27; 348(6303)749-52.
Score: 0.368
The human beta globin locus introduced by YAC transfer exhibits a specific and reproducible pattern of developmental regulation in transgenic mice.
S Porcu ... K M Gaensler
Blood 1997 Dec; 90(11)4602-9.
Score: 0.368
Variegated expression of CD8 alpha resulting from in situ deletion of regulatory sequences.
Anna Garefalaki ... Dimitris Kioussis
Immunity 2002 May; 16(5)635-47.
Score: 0.368
Identification and mapping of nuclear matrix-attachment regions in a one megabase locus of human chromosome 19q13.12: long-range correlation of S/MARs and gene positions.
Igor P Chernov ... E D Sverdlov
J Cell Biochem 2002 ; 84(3)590-600.
Score: 0.368
The Ig(kappa) enhancer influences the ratio of Ig(kappa) versus Ig(lambda) B lymphocytes.
J R Gorman ... F W Alt
Immunity 1996 Sep; 5(3)241-52.
Score: 0.368
Active T-cell receptor genes have intron deoxyribonuclease hypersensitive sites.
E Bier ... A M Maxam
Science 1985 Aug; 229(4713)528-34.
Score: 0.368
Octamer independent activation of transcription from the kappa immunoglobulin germline promoter.
A Prabhu ... B Van Ness
Nucleic Acids Res 1996 Dec; 24(23)4805-11.
Score: 0.368
Complexity of the immunoglobulin light chain V kappa 1 gene family in the New Zealand black mouse.
N C Bailey ... C A Bona
Int Immunol 1991 Aug; 3(8)751-60.
Score: 0.367
Replication initiation patterns in the beta-globin loci of totipotent and differentiated murine cells: evidence for multiple initiation regions.
Mirit I Aladjem ... Geoffrey M Wahl
Mol Cell Biol 2002 Jan; 22(2)442-52.
Score: 0.367
Hypersensitive site 2 specifies a unique function within the human beta-globin locus control region to stimulate globin gene transcription.
J Bungert ... J D Engel
Mol Cell Biol 1999 Apr; 19(4)3062-72.
Score: 0.367
Generation of a mouse strain that produces immunoglobulin kappa chains with human constant regions.
Y R Zou ... K Rajewsky
Science 1993 Nov; 262(5137)1271-4.
Score: 0.367
Transcriptional regulation in endoderm development: characterization of an enhancer controlling Hnf3g expression by transgenesis and targeted mutagenesis.
H Hiemisch ... K H Kaestner
EMBO J 1997 Jul; 16(13)3995-4006.
Score: 0.367
Differences in the kappa opioid receptor mRNA content in distinct brain regions of two inbred mice strains.
A Winkler ... R Spanagel
Neuroreport 1998 May; 9(7)1459-64.
Score: 0.367
The Ly-6E.1 (Sca-1) gene requires a 3' chromatin-dependent region for high-level gamma-interferon-induced hematopoietic cell expression.
A Sinclair ... E Dzierzak
Blood 1996 Apr; 87(7)2750-61.
Score: 0.367
[Transgenic mouse and gene targeting]
J Miyazaki ... F Tashiro
Nippon Rinsho 1992 Sep; 50(9)2261-9.
Score: 0.367
Normal TCRbeta transcription and recombination in the absence of the Jbeta2-Cbeta2 intronic cis element.
C E Whitehurst ... J Chen
Mol Immunol 2001 Jan; 38(1)55-63.
Score: 0.367
cis regulation of the keratin 18 gene in transgenic mice.
N S Neznanov ... R G Oshima
Mol Cell Biol 1993 Mar; 13(3)1815-23.
Score: 0.367
The nucleotide sequence of a 5.5-kilobase DNA segment containing the mouse kappa immunoglobulin J and C region genes.
E E Max ... P Leder
J Biol Chem 1981 May; 256(10)5116-20.
Score: 0.367
Both locus control region and proximal regulatory elements direct the developmental regulation of beta-globin gene cluster.
X j Ji ... C c Liang
J Cell Biochem 2000 Jan; 76(3)376-85.
Score: 0.366
Evolution of human immunoglobulin kappa J region genes.
P A Hieter ... P Leder
J Biol Chem 1982 Feb; 257(3)1516-22.
Score: 0.366
Stimulation of kappa light-chain gene rearrangement by the immunoglobulin mu heavy chain in a pre-B-cell line.
A M Shapiro ... A L DeFranco
Mol Cell Biol 1993 Sep; 13(9)5679-90.
Score: 0.366
Structure of a mouse erythroid 5-aminolevulinate synthase gene and mapping of erythroid-specific DNAse I hypersensitive sites.
D S Schoenhaut ... P J Curtis
Nucleic Acids Res 1989 Sep; 17(17)7013-28.
Score: 0.366
Chromosomal assignment of the mouse kappa light chain genes.
D Swan ... F H Ruddle
Proc Natl Acad Sci U S A 1979 Jun; 76(6)2735-9.
Score: 0.365
Homologous recombination between transferred and chromosomal immunoglobulin kappa genes.
M D Baker ... M J Shulman
Mol Cell Biol 1988 Oct; 8(10)4041-7.
Score: 0.365
Constitutive expression of the Id1 gene impairs mouse B cell development.
X H Sun
Cell 1994 Dec; 79(5)893-900.
Score: 0.365
Accurate 5' splice-site selection in mouse kappa immunoglobulin light chain premessenger RNAs is not cell-type-specific.
D H Kedes ... J A Steitz
Proc Natl Acad Sci U S A 1987 Nov; 84(22)7928-32.
Score: 0.365
Structure and expression of a human subgroup II immunoglobulin kappa gene.
L Weir ... P Leder
Nucleic Acids Res 1986 May; 14(9)3957-70.
Score: 0.365
Identification of an octamer-binding site in the mouse kappa light-chain immunoglobulin enhancer.
R A Currie ... R G Roeder
Mol Cell Biol 1989 Oct; 9(10)4239-47.
Score: 0.365
Murine V kappa gene expression does not follow the VH paradigm.
A Kaushik ... G Kelsoe
J Exp Med 1989 May; 169(5)1859-64.
Score: 0.365
Conserved regulatory elements in the type I DNA topoisomerase gene promoters of mouse and man.
B Baumgärtner ... R Knippers
Biochim Biophys Acta 1994 May; 1218(1)123-7.
Score: 0.365
DNase I hypersensitive sites in the chromatin of human mu immunoglobulin heavy-chain genes.
F C Mills ... H J Gould
Nature 1983 Dec 22-1984 Jan 4; 306(5945)809-12.
Score: 0.365
Identification of two evolutionarily conserved and functional regulatory elements in intron 2 of the human BRCA1 gene.
Stacey L Wardrop ... Melissa A Brown
Genomics 2005 Sep; 86(3)316-28.
Score: 0.364
The inactivation of the XP-C gene does not affect somatic hypermutation or class switch recombination of immunoglobulin genes.
H M Shen ... U Storb
Mol Immunol 1997 May; 34(7)527-33.
Score: 0.364
Gelatinase B/lacZ transgenic mice, a model for mapping gelatinase B expression during developmental and injury-related tissue remodeling.
R Mohan ... M E Fini
J Biol Chem 1998 Oct; 273(40)25903-14.
Score: 0.364
Expression of an idiotype (Id-460) during in vivo anti-dinitrophenyl antibody responses. I. Mapping of genes for Id-460 expression to the variable region of immunoglobulin heavy-chain locus and to the variable region of immunoglobulin kappa-light-chain locus.
E A Dzierzak ... P D Gottlieb
J Exp Med 1980 Sep; 152(3)720-9.
Score: 0.364
A recombination silencer that specifies heterochromatin positioning and ikaros association in the immunoglobulin kappa locus.
Zhe Liu ... William T Garrard
Immunity 2006 Apr; 24(4)405-15.
Score: 0.364
Matrix attachment regions enhance transcription of a downstream transgene and the accessibility of its promoter region to micrococcal nuclease.
Yuji Fukuda ... Satoshi Nishikawa
Plant Mol Biol 2003 Mar; 51(5)665-75.
Score: 0.363
A role for nuclear NF-kappaB in B-cell-specific demethylation of the Igkappa locus.
A Kirillov ... Y Bergman
Nat Genet 1996 Aug; 13(4)435-41.
Score: 0.363
Dynamic reorganization of chromatin structure and selective DNA demethylation prior to stable enhancer complex formation during differentiation of primary hematopoietic cells in vitro.
Hiromi Tagoh ... Constanze Bonifer
Blood 2004 Apr; 103(8)2950-5.
Score: 0.363
Direct evidence for intrastrand DNA inversion of kappa immunoglobulin gene segments in two murine plasmacytomas.
R Feddersen ... B Van Ness
Nucleic Acids Res 1989 Dec; 17(23)9797-809.
Score: 0.363
A hypersensitive site in hsp70 chromatin requires adjacent not internal DNA sequence.
N A Costlow ... J T Lis
Nature 1985 Jan 10-18; 313(5998)147-9.
Score: 0.363
Tissue-specific deoxyribonuclease I-hypersensitive sites in the vicinity of the immunoglobulin C lambda cluster of man.
H Asenbauer ... H G Klobeck
Eur J Immunol 1996 Jan; 26(1)142-50.
Score: 0.362
Handicapped retroviral vectors efficiently transduce foreign genes into hematopoietic stem cells.
R G Hawley ... B Mintz
Proc Natl Acad Sci U S A 1987 Apr; 84(8)2406-10.
Score: 0.362
The cis-acting elements known to regulate c-myc expression ex vivo are not sufficient for correct transcription in vivo.
A Lavenu ... D Morello
Oncogene 1994 Feb; 9(2)527-36.
Score: 0.362
Beyond the locus control region: new light on beta-globin locus regulation.
X G Li ... C C Liang
Int J Biochem Cell Biol 2001 Sep; 33(9)914-23.
Score: 0.362
Dissection of the mouse N-ras gene upstream regulatory sequences and identification of the promoter and a negative regulatory element.
R Paciucci ... A Pellicer
Mol Cell Biol 1991 Mar; 11(3)1334-43.
Score: 0.362
Diversity of immunoglobulin kappa light chain gene rearrangements and evidence for somatic mutation in V kappa IV family gene segments in X-linked agammaglobulinemia.
E Timmers ... R K Schuurman
Eur J Immunol 1993 Mar; 23(3)619-24.
Score: 0.362
Beta-globin gene switching and DNase I sensitivity of the endogenous beta-globin locus in mice do not require the locus control region.
M A Bender ... M Groudine
Mol Cell 2000 Feb; 5(2)387-93.
Score: 0.361
Cloning and functional characterization of the murine caspase-3 gene promoter.
Laurent Sabbagh ... Rafick-Pierre Sékaly
DNA Cell Biol 2006 Feb; 25(2)104-15.
Score: 0.361
Structure of rearranged and germ-line rabbit V kappa genes indicated that the CDR3 is encoded by the V kappa gene.
H Ayadi ... P N Marche
Eur J Immunol 1990 Feb; 20(2)259-64.
Score: 0.361
Evolution of the immunoglobulin kappa light chain locus in the rabbit: evidence for differential gene conversion events.
M A Akimenko ... F Rougeon
Proc Natl Acad Sci U S A 1986 Jul; 83(14)5180-3.
Score: 0.361
Specific expression of a foreign beta-globin gene in erythroid cells of transgenic mice.
K Chada ... F Costantini
Nature 1985 Mar 28-Apr 3; 314(6009)377-80.
Score: 0.360
Targeted remodeling of human beta-globin promoter chromatin structure produces increased expression and decreased silencing.
N Iler ... C H Lowrey
Blood Cells Mol Dis 1999 Feb; 25(1)47-60.
Score: 0.360
Looping and interaction between hypersensitive sites in the active beta-globin locus.
Bas Tolhuis ... Wouter de Laat
Mol Cell 2002 Dec; 10(6)1453-65.
Score: 0.360
Effect of deletion of 5'HS3 or 5'HS2 of the human beta-globin locus control region on the developmental regulation of globin gene expression in beta-globin locus yeast artificial chromosome transgenic mice.
K R Peterson ... G Stamatoyannopoulos
Proc Natl Acad Sci U S A 1996 Jun; 93(13)6605-9.
Score: 0.360
A human immunoglobulin lambda locus is similarly well expressed in mice and humans.
A V Popov ... M Brüggemann
J Exp Med 1999 May; 189(10)1611-20.
Score: 0.360
The human immunoglobulin kappa locus consists of two copies that are organized in opposite polarity.
G M Weichhold ... H G Zachau
Genomics 1993 May; 16(2)503-11.
Score: 0.360
Three new immunoglobulin kappa variable (Igk-V) gene segments in the mouse.
D A Ramsden ... G E Wu
Immunogenetics 1995 ; 41(5)334.
Score: 0.360
The V kappa genes of the L regions and the repertoire of V kappa gene sequences in the human germ line.
C Huber ... H G Zachau
Eur J Immunol 1993 Nov; 23(11)2868-75.
Score: 0.359
Multiple control elements are required for expression of the human CD34 gene.
H S Radomska ... D G Tenen
Gene 1998 Nov; 222(2)305-18.
Score: 0.359
Protein:DNA interactions at chromosomal loop attachment sites.
V C Blasquez ... W T Garrard
Genome 1989 ; 31(2)503-9.
Score: 0.359
A dominant control region from the human beta-globin locus conferring integration site-independent gene expression.
D Talbot ... D R Greaves
Nature 1989 Mar; 338(6213)352-5.
Score: 0.359
Targeted insertion of a variable region gene into the immunoglobulin heavy chain locus.
S Taki ... K Rajewsky
Science 1993 Nov; 262(5137)1268-71.
Score: 0.359
Hypersensitive site 7 of the TH2 locus control region is essential for expressing TH2 cytokine genes and for long-range intrachromosomal interactions.
Gap Ryol Lee ... Richard A Flavell
Nat Immunol 2005 Jan; 6(1)42-8.
Score: 0.359
Retrovirus-induced lethal mutation in collagen I gene of mice is associated with an altered chromatin structure.
M Breindl ... R Jaenisch
Cell 1984 Aug; 38(1)9-16.
Score: 0.358
Evolutionary relationships and polymorphisms among V kappa 10 genes from inbred and wild-derived inbred mice.
Sean P Fitzsimmons ... Marjorie A Shapiro
Immunogeneti