FRISC: The Faculty Research Interests Science Comparator

Jonathan M. (Jon) Graff, M.D., Ph.D.
Assistant Professor, Center for Developmental Biology and Departments of Molecular
Biology and Internal Medicine
Genetics and
Development
Office: (214) 648-1481, (214) 648-1482, (214) 648-1612
FAX: (214) 648-1960
Building NB, Room 5.228
Email: graff02@utsw.swmed.edu
Center for Developmental Biology: http://www2.utsouthwestern.edu/devbio/

New This Month | New This Year | Abstract | Selected Publications | FRISC Statistics Results - FULL MEDLINE:

Effects of subchronic exposures to concentrated ambient particles (CAPs) in mice. III. Acute and chronic effects of CAPs on heart rate, heart-rate fluctuation, and body temperature.
Jing-Shiang Hwang ... Lung Chi Chen
Inhal Toxicol 2005 Apr; 17(4-5)199-207.

Score: 0.575
New aspects of Wnt signaling pathways in higher vertebrates.
J Huelsken ... W Birchmeier
Curr Opin Genet Dev 2001 Oct; 11(5)547-53.

Score: 0.459
Immunohistochemical expression of Smads 1-6 in the 15-day gestation mouse embryo: signaling by BMPs and TGF-betas.
K C Flanders ... A B Roberts
Dev Dyn 2001 Feb; 220(2)141-54.

Score: 0.449
Mechanism and function of signal transduction by the Wnt/beta-catenin and Wnt/Ca2+ pathways.
J R Miller ... R T Moon
Oncogene 1999 Dec; 18(55)7860-72.

Score: 0.442
Crossing Smads.
J L Wrana
Sci STKE 2000 Mar; 2000(23)RE1.

Score: 0.420
Chemosensation: molecular mechanisms in worms and mammals.
B C Prasad ... R R Reed
Trends Genet 1999 Apr; 15(4)150-3.

Score: 0.419
[Receptor and disease: genetic perspective]
K Yamamura
Rinsho Byori 2000 May; 48(5)416-22.

Score: 0.410
Tumor formation by genetic mutations in the components of the Wnt signaling pathway.
Akira Kikuchi
Cancer Sci 2003 Mar; 94(3)225-9.

Score: 0.407
Recent advances in understanding signal transduction pathways in worms and flies.
J B Duffy ... N Perrimon
Curr Opin Cell Biol 1996 Apr; 8(2)231-8.

Score: 0.407
Interactions between BMP and Wnt signaling pathways in mammalian cancers.
Hui-Chuan Huang ... Peter S Klein
Cancer Biol Ther 2004 Jul; 3(7)676-8.

Score: 0.399
The Wnt signaling pathway and its role in tumor development.
B Lustig ... J Behrens
J Cancer Res Clin Oncol 2003 Apr; 129(4)199-221.

Score: 0.398
TGF-beta signaling by Smad proteins.
K Miyazono ... C H Heldin
Adv Immunol 2000 ; 75()115-57.

Score: 0.397
Signaling of transforming growth factor-beta family members through Smad proteins.
S Itoh ... P Ten Dijke
Eur J Biochem 2000 Dec; 267(24)6954-67.

Score: 0.396
Mutations in the tumor suppressors Smad2 and Smad4 inactivate transforming growth factor beta signaling by targeting Smads to the ubiquitin-proteasome pathway.
J Xu ... L Attisano
Proc Natl Acad Sci U S A 2000 Apr; 97(9)4820-5.

Score: 0.393
Intracellular signaling of the TGF-beta superfamily by Smad proteins.
M Kawabata ... K Miyazono
Ann N Y Acad Sci 1999 ; 886()73-82.

Score: 0.393
Non-canonical Wnt signaling in Xenopus: regulation of axis formation and gastrulation.
Michael Kühl
Semin Cell Dev Biol 2002 Jun; 13(3)243-9.

Score: 0.393
Smads are the central component in transforming growth factor-beta signaling.
R W Padgett ... C Evangelista
Pharmacol Ther 1998 Apr; 78(1)47-52.

Score: 0.392
Identification and comparative expression analyses of Daam genes in mouse and Xenopus.
Masa-aki Nakaya ... Terry P Yamaguchi
Gene Expr Patterns 2004 Nov; 5(1)97-105.

Score: 0.392
Receptor-regulated Smads in TGF-beta signaling.
Fang Liu
Front Biosci 2003 Sep; 8()s1280-303.

Score: 0.392
Genetic approaches to tyrosine kinase signaling pathways in the immune system.
Pamela L Schwartzberg
Immunol Res 2003 ; 27(2-3)481-8.

Score: 0.391
Visualization of endogenous BMP signaling during Xenopus development.
T Kurata ... N Ueno
Differentiation 2001 Feb; 67(1-2)33-40.

Score: 0.389
Similarities and differences between the Wnt and reelin pathways in the forming brain.
Orly Reiner ... Tamar Sapir
Mol Neurobiol 2005 ; 31(1-3)117-34.

Score: 0.388
Mouse models of holoprosencephaly.
Monica Hayhurst ... Susan K McConnell
Curr Opin Neurol 2003 Apr; 16(2)135-41.

Score: 0.385
From the sarcomere to the nucleus: role of genetics and signaling in structural heart disease.
R L Nicol ... E N Olson
Annu Rev Genomics Hum Genet 2000 ; 1()179-223.

Score: 0.384
Transcriptional regulation by Smads: crosstalk between the TGF-beta and Wnt pathways.
A Letamendia ... L Attisano
J Bone Joint Surg Am 2001 ; 83-A Suppl 1(Pt 1)S31-9.

Score: 0.381
Canonical and non-canonical Wnt signaling pathways in Caenorhabditis elegans: variations on a common signaling theme.
Hendrik C Korswagen
Bioessays 2002 Sep; 24(9)801-10.

Score: 0.381
Signal-transduction defects in T cells.
E Grunebaum ... C M Roifman
Clin Rev Allergy Immunol 2001 Feb; 20(1)27-42.

Score: 0.378
TGFbeta signaling pathways and human diseases.
R W Padgett
Cancer Metastasis Rev 1999 ; 18(2)247-59.

Score: 0.378
Specificity in signaling pathways: assembly into multimolecular signaling complexes.
S Tsunoda ... C S Zuker
Curr Opin Genet Dev 1998 Aug; 8(4)419-22.

Score: 0.378
TGF-beta signaling in colon cancer cells.
Fazhi Li ... Tien C Ko
World J Surg 2005 Mar; 29(3)306-11.

Score: 0.377
Crosstalk mechanisms between the mitogen-activated protein kinase pathways and Smad signaling downstream of TGF-beta: implications for carcinogenesis.
Delphine Javelaud ... Alain Mauviel
Oncogene 2005 Aug; 24(37)5742-50.

Score: 0.377
Activin signal transduction pathways.
S A Pangas ... T K Woodruff
Trends Endocrinol Metab 2000 Oct; 11(8)309-14.

Score: 0.376
A model of pattern formation based on signaling pathways.
F W Cummings
J Theor Biol 2000 Nov; 207(1)107-16.

Score: 0.374
Cross-regulation of Wnt signaling and cell adhesion.
Alexandra Schambony ... Dietmar Gradl
Differentiation 2004 Sep; 72(7)307-18.

Score: 0.374
Wnts and wing: Wnt signaling in vertebrate limb development and musculoskeletal morphogenesis.
Yingzi Yang
Birth Defects Res C Embryo Today 2003 Nov; 69(4)305-17.

Score: 0.373
Developmental roles of heparan sulfate proteoglycans in Drosophila.
Xinhua Lin ... Norbert Perrimon
Glycoconj J 2002 May-Jun; 19(4-5)363-8.

Score: 0.371
Functional analysis of the TGFbeta receptor/Smad pathway through gene ablation in mice.
M J Goumans ... C Mummery
Int J Dev Biol 2000 Apr; 44(3)253-65.

Score: 0.371
Secreted cell signaling molecules in axon guidance.
Shingo Yoshikawa ... John B Thomas
Curr Opin Neurobiol 2004 Feb; 14(1)45-50.

Score: 0.370
Molecular mechanisms in gliomagenesis.
Esther Hulleman ... Kristian Helin
Adv Cancer Res 2005 ; 94()1-27.

Score: 0.370
Signal transduction of the TGF-beta superfamily by Smad proteins.
M Kawabata ... K Miyazono
J Biochem (Tokyo) 1999 Jan; 125(1)9-16.

Score: 0.369
TGF-beta signaling, Smads, and tumor suppressors.
R W Padgett ... S Krishna
Bioessays 1998 May; 20(5)382-90.

Score: 0.368
Drosophila wingless: a paradigm for the function and mechanism of Wnt signaling.
E Siegfried ... N Perrimon
Bioessays 1994 Jun; 16(6)395-404.

Score: 0.368
Can't get no SMADisfaction: Smad proteins as positive and negative regulators of TGF-beta family signals.
J L Christian ... T Nakayama
Bioessays 1999 May; 21(5)382-90.

Score: 0.368
Intracellular BMP signaling regulation in vertebrates: pathway or network?
A von Bubnoff ... K W Cho
Dev Biol 2001 Nov; 239(1)1-14.

Score: 0.365
Signal transduction pathways in human epidermis.
Lars Iversen ... Knud Kragballe
Eur J Dermatol 2005 Jan-Feb; 15(1)4-12.

Score: 0.364
Intracellular signaling by the neural cell adhesion molecule.
Gro Klitgaard Povlsen ... Elisabeth Bock
Neurochem Res 2003 Jan; 28(1)127-41.

Score: 0.364
Smads and early developmental signaling by the TGFbeta superfamily.
M Whitman
Genes Dev 1998 Aug; 12(16)2445-62.

Score: 0.364
Signal transduction by the TGF-beta superfamily.
Liliana Attisano ... Jeffrey L Wrana
Science 2002 May; 296(5573)1646-7.

Score: 0.363
Src-family kinases: rheostats of immune cell signaling.
Clifford A Lowell
Mol Immunol 2004 Jul; 41(6-7)631-43.

Score: 0.363
The BMP signaling and in vivo bone formation.
Xu Cao ... Di Chen
Gene 2005 Aug; 357(1)1-8.

Score: 0.361
Role of phosphoinositide 3-kinase signaling in mast cells: new insights from knockout mouse studies.
Taro Fukao ... Shigeo Koyasu
J Mol Med 2003 Sep; 81(9)524-35.

Score: 0.360
Microtubules and signal transduction.
G G Gundersen ... T A Cook
Curr Opin Cell Biol 1999 Feb; 11(1)81-94.

Score: 0.359
Expression of Smad proteins in human colorectal cancer.
O Korchynskyi ... S Souchelnytskyi
Int J Cancer 1999 Jul; 82(2)197-202.

Score: 0.359
Wnt/Frizzled signaling in hepatocellular carcinoma.
Han Chu Lee ... Jack R Wands
Front Biosci 2006 ; 11()1901-15.

Score: 0.359
Intercellular growth factor signaling and the development of mouse tracheal submucosal glands.
Emma L Rawlins ... Brigid L M Hogan
Dev Dyn 2005 Aug; 233(4)1378-85.

Score: 0.359
The promise and perils of Wnt signaling through beta-catenin.
Randall T Moon ... Norbert Perrimon
Science 2002 May; 296(5573)1644-6.

Score: 0.358
The role of transcription factors involved in TGFbeta superfamily signaling during development.
M Watanabe ... M Whitman
Cell Mol Biol (Noisy-le-grand) 1999 Jul; 45(5)537-43.

Score: 0.358
The murine gastrin promoter is synergistically activated by transforming growth factor-beta/Smad and Wnt signaling pathways.
Shi Lei ... Timothy C Wang
J Biol Chem 2004 Oct; 279(41)42492-502.

Score: 0.357
Sugars as signaling molecules.
J Sheen ... J C Jang
Curr Opin Plant Biol 1999 Oct; 2(5)410-8.

Score: 0.356
Reduced expression of neural cell adhesion molecule induces metastatic dissemination of pancreatic beta tumor cells.
A K Perl ... G Christofori
Nat Med 1999 Mar; 5(3)286-91.

Score: 0.354
TGF-beta/SMAD signaling and its involvement in tumor progression.
K Miyazono
Biol Pharm Bull 2000 Oct; 23(10)1125-30.

Score: 0.354
The Smads.
L Attisano ... S Tuen Lee-Hoeflich
Genome Biol 2001 ; 2(8)REVIEWS3010.

Score: 0.352
Hedgehog signal transduction: from flies to vertebrates.
M Murone ... F J de Sauvage
Exp Cell Res 1999 Nov; 253(1)25-33.

Score: 0.352
Pharmacologic control of intracellular signaling pathways: from research to therapy.
J Hakim
J Cardiovasc Pharmacol 1995 ; 25 Suppl 2()S106-13.

Score: 0.352
Signal transduction: multiple pathways, multiple options for therapy.
C H Heldin
Stem Cells 2001 ; 19(4)295-303.

Score: 0.352
TGFbeta and Wnt pathway cross-talk.
Liliana Attisano ... Etienne Labbé
Cancer Metastasis Rev 2004 Jan-Jun; 23(1-2)53-61.

Score: 0.351
Vulval development in Caenorhabditis elegans.
K Kornfeld
Trends Genet 1997 Feb; 13(2)55-61.

Score: 0.351
Signaling for survival and apoptosis in the immune system.
Tak W Mak ... Wen-Chen Yeh
Arthritis Res 2002 ; 4 Suppl 3()S243-52.

Score: 0.350
Similarities between the Hedgehog and Wnt signaling pathways.
Daniel Kalderon
Trends Cell Biol 2002 Nov; 12(11)523-31.

Score: 0.350
Wnt signaling and breast cancer.
Louise R Howe ... Anthony M C Brown
Cancer Biol Ther 2004 Jan; 3(1)36-41.

Score: 0.349
Wnt signaling: physiology and pathology.
Céline Prunier ... Philip H Howe
Growth Factors 2004 Sep; 22(3)141-50.

Score: 0.349
Signaling molecules derived from the cholesterol biosynthetic pathway: mechanisms of action and possible roles in human disease.
P A Edwards ... J Ericsson
Curr Opin Lipidol 1998 Oct; 9(5)433-40.

Score: 0.349
Wnt signaling in B and T lymphocytes.
Ya-Wei Qiang ... Stuart Rudikoff
Front Biosci 2004 Jan; 9()1000-10.

Score: 0.348
The Smads.
C S Hill
Int J Biochem Cell Biol 1999 Nov; 31(11)1249-54.

Score: 0.348
The role of Wnt genes in vertebrate development.
M E Dickinson ... A P McMahon
Curr Opin Genet Dev 1992 Aug; 2(4)562-6.

Score: 0.347
Wnt signaling: a complex issue.
Bart Hendriks ... Ernst Reichmann
Biol Res 2002 ; 35(2)277-86.

Score: 0.347
Remarkable versatility of Smad proteins in the nucleus of transforming growth factor-beta activated cells.
K Verschueren ... D Huylebroeck
Cytokine Growth Factor Rev 1999 Sep-Dec; 10(3-4)187-99.

Score: 0.347
Lef-1 and Tcf-3 transcription factors mediate tissue-specific Wnt signaling during Xenopus development.
Giulietta Roël ... Stefan Hoppler
Curr Biol 2002 Nov; 12(22)1941-5.

Score: 0.346
WNTs modulate cell fate and behavior during vertebrate development.
R T Moon ... M Torres
Trends Genet 1997 Apr; 13(4)157-62.

Score: 0.346
Functional conservation of the Wnt signaling pathway revealed by ectopic expression of Drosophila dishevelled in Xenopus.
U Rothbächer ... K W Cho
Dev Biol 1995 Aug; 170(2)717-21.

Score: 0.345
Secreted inducers in vertebrate eye development: more functions for old morphogens.
Pilar Esteve ... Paola Bovolenta
Curr Opin Neurobiol 2006 Feb; 16(1)13-9.

Score: 0.345
Specification of developmental fates in ascidian embryos: molecular approach to maternal determinants and signaling molecules.
Hiroki Nishida
Int Rev Cytol 2002 ; 217()227-76.

Score: 0.345
Role of TAK1 and TAB1 in BMP signaling in early Xenopus development.
H Shibuya ... N Ueno
EMBO J 1998 Feb; 17(4)1019-28.

Score: 0.345
Combinatorial gene regulation by Bmp and Wnt in zebrafish posterior mesoderm formation.
Daniel P Szeto ... David Kimelman
Development 2004 Aug; 131(15)3751-60.

Score: 0.345
Wnt/frizzled signaling during vertebrate retinal development.
Terence J Van Raay ... Monica L Vetter
Dev Neurosci 2004 ; 26(5-6)352-8.

Score: 0.345
[TGF-beta and its receptors]
Y Yuasa
Gan To Kagaku Ryoho 1997 Sep; 24(11)1460-4.

Score: 0.344
Tumor suppressor PTEN: modulator of cell signaling, growth, migration and apoptosis.
K M Yamada ... M Araki
J Cell Sci 2001 Jul; 114(Pt 13)2375-82.

Score: 0.344
Molecular signals regulating proliferation of stem and progenitor cells in mouse olfactory epithelium.
Shimako Kawauchi ... Anne L Calof
Dev Neurosci 2004 Mar-Aug; 26(2-4)166-80.

Score: 0.344
Signaling cascade coordinating growth of dorsal and ventral tissues of the vertebrate brain, with special reference to the involvement of Sonic Hedgehog signaling.
Makoto Ishibashi ... Kohei Shiota
Anat Sci Int 2005 Mar; 80(1)30-6.

Score: 0.343
Role of transforming growth factor-beta signaling in cancer.
M P de Caestecker ... A B Roberts
J Natl Cancer Inst 2000 Sep; 92(17)1388-402.

Score: 0.343
Role of TGFbeta signaling in skin carcinogenesis.
X J Wang
Microsc Res Tech 2001 Feb; 52(4)420-9.

Score: 0.342
Ras-MAP kinase signaling pathways and control of cell proliferation: relevance to cancer therapy.
Paul Shapiro
Crit Rev Clin Lab Sci 2002 Sep; 39(4-5)285-330.

Score: 0.342
Genetic engineering to study testicular tumorigenesis.
Wei Yan ... Martin M Matzuk
APMIS 2003 Jan; 111(1)174-81; discussion 182-3.

Score: 0.342
Cell signaling pathways altered by natural chemopreventive agents.
Fazlul H Sarkar ... Yiwei Li
Mutat Res 2004 Nov; 555(1-2)53-64.

Score: 0.342
Characterization of Wnt signaling components and activation of the Wnt canonical pathway in the murine retina.
Hong Liu ... Valerie A Wallace
Dev Dyn 2003 Jul; 227(3)323-34.

Score: 0.342
Ca2+-dependent signaling pathways in the heart: potential drug targets for cardiac disease.
Jeffrey Lynch ... Marek Michalak
Curr Drug Targets Cardiovasc Haematol Disord 2002 Jun; 2(1)1-11.

Score: 0.342
Cellular mechanisms of wingless/Wnt signal transduction.
H Dierick ... A Bejsovec
Curr Top Dev Biol 1999 ; 43()153-90.

Score: 0.341
Roles of Wnt proteins in neural development and maintenance.
A Patapoutian ... L F Reichardt
Curr Opin Neurobiol 2000 Jun; 10(3)392-9.

Score: 0.341
Activation of Wnt/beta-catenin/Tcf signaling in mouse skin carcinogenesis.
Neehar Bhatia ... Vladimir S Spiegelman
Mol Carcinog 2005 Apr; 42(4)213-21.

Score: 0.341
Modulation of endogenous Smad expression in normal skin fibroblasts by transforming growth factor-beta.
Y Mori ... J Varga
Exp Cell Res 2000 Aug; 258(2)374-83.

Score: 0.340
The Fas signaling connection between autoimmunity and embryonic lethality.
H C Hsu ... J D Mountz
J Clin Immunol 2001 Jan; 21(1)1-14.

Score: 0.340
The functions of insulin signaling: size isn't everything, even in Drosophila.
Deborah C I Goberdhan ... Clive Wilson
Differentiation 2003 Sep; 71(7)375-97.

Score: 0.339
Wnts, signaling and sulfates.
S S Blair
Sci STKE 2001 Sep; 2001(101)PE32.

Score: 0.339
Vital elements of the Wnt-Frizzled signaling pathway in the nervous system.
Faqi Li ... Kenneth Maiese
Curr Neurovasc Res 2005 Oct; 2(4)331-40.

Score: 0.338
Mechanisms of Wnt signaling in development.
A Wodarz ... R Nusse
Annu Rev Cell Dev Biol 1998 ; 14()59-88.

Score: 0.338
The TGF-beta family: signaling pathways, developmental roles, and tumor suppressor activities.
Aaron N Johnson ... Stuart J Newfeld
ScientificWorldJournal 2002 Apr; 2()892-925.

Score: 0.338
Signaling through the B cell antigen receptor in developing B cells.
T M Yankee ... E A Clark
Rev Immunogenet 2000 ; 2(2)185-203.

Score: 0.338
TGF-beta induces proangiogenic and antiangiogenic factors via parallel but distinct Smad pathways.
Takahiko Nakagawa ... Richard J Johnson
Kidney Int 2004 Aug; 66(2)605-13.

Score: 0.338
Stress signaling in Drosophila.
B E Stronach ... N Perrimon
Oncogene 1999 Nov; 18(45)6172-82.

Score: 0.338
Wnt signaling in disease and in development.
Roel Nusse
Cell Res 2005 Jan; 15(1)28-32.

Score: 0.337
Divergence and convergence of TGF-beta/BMP signaling.
K Miyazono ... H Inoue
J Cell Physiol 2001 Jun; 187(3)265-76.

Score: 0.337
A SMAD ubiquitin ligase targets the BMP pathway and affects embryonic pattern formation.
H Zhu ... G H Thomsen
Nature 1999 Aug; 400(6745)687-93.

Score: 0.336
Molecular cloning of Fyn-associated molecules in the mouse central nervous system.
N Kai ... T Yagi
J Neurosci Res 1997 Jun; 48(5)407-24.

Score: 0.336
TGF-beta and the Smad signal transduction pathway.
Arun Mehra ... Jeffrey L Wrana
Biochem Cell Biol 2002 ; 80(5)605-22.

Score: 0.336
Application of signal transduction inhibition as a therapeutic strategy for central nervous system tumors.
I F Pollack ... M Erff
Pediatr Neurosurg 1998 Nov; 29(5)228-44.

Score: 0.336
An LDL-receptor-related protein mediates Wnt signalling in mice.
K I Pinson ... W C Skarnes
Nature 2000 Sep; 407(6803)535-8.

Score: 0.335
The signaling pathways in tissue morphogenesis: a lesson from mice with eye-open at birth phenotype.
Ying Xia ... Winston W-Y Kao
Biochem Pharmacol 2004 Sep; 68(6)997-1001.

Score: 0.335
Small molecules and future regenerative medicine.
Sheng Ding ... Peter G Schultz
Curr Top Med Chem 2005 ; 5(4)383-95.

Score: 0.335
Thrombopoietin signal transduction: studies from cell lines and primary cells.
J G Drachman ... K Kaushansky
Methods 1999 Mar; 17(3)238-49.

Score: 0.335
Axis determination by inhibition of Wnt signaling in Xenopus.
K Itoh ... S Y Sokol
Genes Dev 1999 Sep; 13(17)2328-36.

Score: 0.335
B cell receptor signaling and autoimmunity.
P Hasler ... M Zouali
FASEB J 2001 Oct; 15(12)2085-98.

Score: 0.335
Analysis of Fz10 expression in mouse embryos.
Amy P Nunnally ... Brian A Parr
Dev Genes Evol 2004 Mar; 214(3)144-8.

Score: 0.334
[Effect of BMP signaling in cartilage and bone formation]
Noriyuki Tsumaki
Clin Calcium 2006 Apr; 16(4)138-42.

Score: 0.333
TGF-beta signaling from receptors to the nucleus.
A B Roberts
Microbes Infect 1999 Dec; 1(15)1265-73.

Score: 0.333
Growth regulatory factors and carcinogenesis: the roles played by transforming growth factor beta, its receptors and signaling pathways.
D L Kelly ... A Rizzino
Anticancer Res 1999 Nov-Dec; 19(6A)4791-807.

Score: 0.332
Notch signaling in mammary development and oncogenesis.
Robert Callahan ... Sean E Egan
J Mammary Gland Biol Neoplasia 2004 Apr; 9(2)145-63.

Score: 0.332
Dishevelled: at the crossroads of divergent intracellular signaling pathways.
M Boutros ... M Mlodzik
Mech Dev 1999 May; 83(1-2)27-37.

Score: 0.332
A genome-wide study of gene activity reveals developmental signaling pathways in the preimplantation mouse embryo.
Q Tian Wang ... Magdalena Zernicka-Goetz
Dev Cell 2004 Jan; 6(1)133-44.

Score: 0.332
Role of the BMK1/ERK5 signaling pathway: lessons from knockout mice.
Masaaki Hayashi ... Jiing-Dwan Lee
J Mol Med 2004 Dec; 82(12)800-8.

Score: 0.331
[Functional study on TGF-beta/Smads signaling pathway in human ovarian cancer cells]
Yun-Yan Zhang ... Song-Bin Fu
Yi Chuan Xue Bao 2004 Aug; 31(8)759-65.

Score: 0.331
Heart development: learning from mistakes.
David G McFadden ... Eric N Olson
Curr Opin Genet Dev 2002 Jun; 12(3)328-35.

Score: 0.331
Integrins and inside-out signal transduction: converging signals from PKC and PIP3.
W Kolanus ... B Seed
Curr Opin Cell Biol 1997 Oct; 9(5)725-31.

Score: 0.331
Roles of cell-extrinsic growth factors in vertebrate eye pattern formation and retinogenesis.
Xian-Jie Yang
Semin Cell Dev Biol 2004 Feb; 15(1)91-103.

Score: 0.330
A genomewide survey of developmentally relevant genes in Ciona intestinalis. VI. Genes for Wnt, TGFbeta, Hedgehog and JAK/STAT signaling pathways.
Kyosuke Hino ... Nori Satoh
Dev Genes Evol 2003 Jun; 213(5-6)264-72.

Score: 0.330
Signaling axis in schwann cell proliferation and differentiation.
Toru Ogata ... Sakae Tanaka
Mol Neurobiol 2006 Feb; 33(1)51-62.

Score: 0.330
Regulation of convergent extension in Xenopus by Wnt5a and Frizzled-8 is independent of the canonical Wnt pathway.
J B Wallingford ... R M Harland
Int J Dev Biol 2001 ; 45(1)225-7.

Score: 0.330
Heart valve development: endothelial cell signaling and differentiation.
Ehrin J Armstrong ... Joyce Bischoff
Circ Res 2004 Sep; 95(5)459-70.

Score: 0.329
Elucidating cell signaling mechanisms using antisense technology.
E Koller ... B P Monia
Trends Pharmacol Sci 2000 Apr; 21(4)142-8.

Score: 0.329
Wnt signaling and dorso-ventral axis specification in vertebrates.
S Y Sokol
Curr Opin Genet Dev 1999 Aug; 9(4)405-10.

Score: 0.329
Signal transduction by cell adhesion receptors and the cytoskeleton: functions of integrins, cadherins, selectins, and immunoglobulin-superfamily members.
R L Juliano
Annu Rev Pharmacol Toxicol 2002 ; 42()283-323.

Score: 0.329
When Wnts antagonize Wnts.
Gilbert Weidinger ... Randall T Moon
J Cell Biol 2003 Sep; 162(5)753-5.

Score: 0.329
JAK/STAT signaling regulates tissue outgrowth and male germline stem cell fate in Drosophila.
Shree Ram Singh ... Steven X Hou
Cell Res 2005 Jan; 15(1)1-5.

Score: 0.329
Connecting COX-2 and Wnt in cancer.
F Gregory Buchanan ... Raymond N DuBois
Cancer Cell 2006 Jan; 9(1)6-8.

Score: 0.329
Negative regulation of TGF-beta signaling in development.
Ye Guang Chen ... An Ming Meng
Cell Res 2004 Dec; 14(6)441-9.

Score: 0.328
Fritz: a secreted frizzled-related protein that inhibits Wnt activity.
T Mayr ... W Risau
Mech Dev 1997 Apr; 63(1)109-25.

Score: 0.328
Principles of MAP kinase signaling specificity in Saccharomyces cerevisiae.
Monica A Schwartz ... Hiten D Madhani
Annu Rev Genet 2004 ; 38()725-48.

Score: 0.328
[Animal ontogenetic cell signaling pathways by the example of Notch cascade of Drosophila melanogaster]
N Ia Vaĭsman
Zh Obshch Biol 2004 Jul-Aug; 65(4)322-33.

Score: 0.328
The Smads: transcriptional regulation and mouse models.
M Datto ... X F Wang
Cytokine Growth Factor Rev 2000 Mar-Jun; 11(1-2)37-48.

Score: 0.328
Mammary ductal and alveolar development: lesson learned from genetically manipulated mice.
M E Dunbar ... J J Wysolmerski
Microsc Res Tech 2001 Jan; 52(2)163-70.

Score: 0.328
Drosophila Wnt/Fz pathways.
Ramanuj DasGupta ... Norbert Perrimon
Sci STKE 2005 May; 2005(283)cm5.

Score: 0.328
Early posterior/ventral fate specification in the vertebrate embryo.
I Muñoz-Sanjuán ... A H-Brivanlou
Dev Biol 2001 Sep; 237(1)1-17.

Score: 0.327
Function of cytokines within the TGF-beta superfamily as determined from transgenic and gene knockout studies in mice.
Ashok B Kulkarni ... John J Letterio
Curr Mol Med 2002 May; 2(3)303-27.

Score: 0.327
[Transforming growth factor-betas: smad signaling and roles in physiopathology]
D Javelaud ... A Mauviel
Pathol Biol (Paris) 2004 Feb; 52(1)50-4.

Score: 0.327
Oncogenic signal transduction and therapeutic strategy for hepatocellular carcinoma.
Shinji Tanaka ... Keizo Sugimachi
Surgery 2002 Jan; 131(1 Suppl)S142-7.

Score: 0.327
Mathematical models of protein kinase signal transduction.
Reinhart Heinrich ... Tom A Rapoport
Mol Cell 2002 May; 9(5)957-70.

Score: 0.327
Signaling pathways in adrenocortical cancer.
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