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How do inositol phosphates regulate calcium signaling?
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Protein tyrosine kinase p59fyn is associated with the T cell receptor-CD3 complex in functional human lymphocytes.
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[Mechanisms of Ca2+ signalling in cells]
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The family of protein kinase C in transmembrane signalling for cellular regulation.
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The role of phosphatidylinositides in stimulus-secretion coupling in the exocrine pancreas.
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[Phosphoinositide metabolism and the formation of the calcium signal in cells]
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The role of phosphoinositide metabolism in signal transduction in secretory cells.
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Receptors, inositol polyphosphates and intracellular Ca2+.
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The mechanism for synergism between phospholipase C- and adenylylcyclase-linked hormones in liver. Cyclic AMP-dependent kinase augments inositol trisphosphate-mediated Ca2+ mobilization without increasing the cellular levels of inositol polyphosphates.
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Mammalian phosphoinositide-specific phospholipase C isoenzymes.
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[The plasticity of the snail cholinoreceptor neurons following exposures to the inositol 1,4,5-triphosphate- and Ca2(+)-dependent mobilization of deposited Ca2(+) and the level of phosphatidic acid]
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A novel 90-kDa tyrosine-phosphorylated protein associated with TCR complex in thymocytes.
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Inositol trisphosphate, a novel second messenger in cellular signal transduction.
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Activation of calcium entry by the tumor promoter thapsigargin in parotid acinar cells. Evidence that an intracellular calcium pool and not an inositol phosphate regulates calcium fluxes at the plasma membrane.
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Extracellular Ca2+ sensing, regulation of parathyroid cell function, and role of Ca2+ and other ions as extracellular (first) messengers.
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Calcium and T lymphocyte activation.
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Inositol trisphosphate receptor mediated spatiotemporal calcium signalling.
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Neuropeptide inhibition of voltage-gated calcium channels mediated by mobilization of intracellular calcium.
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Inositol trisphosphate and diacylglycerol as second messengers.
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Psychostimulants, L-type calcium channels, kinases, and phosphatases.
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Role of protein kinase C in transmembrane signaling.
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Specificity of inositol phosphate-stimulated Ca2+ mobilization from Swiss-mouse 3T3 cells.
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Calcium influx and its control by calcium release.
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Inositol 1,4,5-trisphosphate receptors and calcium signaling.
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Independent regulation of Ca2+ entry and release from internal stores in activated B cells.
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Extracellular ATP causes Ca2(+)-dependent and -independent insulin secretion in RINm5F cells. Phospholipase C mediates Ca2+ mobilization but not Ca2+ influx and membrane depolarization.
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Ca2+ oscillations in neutrophils triggered by immune complexes result from Ca2+ influx.
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Phospholipase C beta and membrane action of calcitriol and estradiol.
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Chemoattractant receptor promotion of Ca2+ influx across the plasma membrane of HL-60 cells. A role for cytosolic free calcium elevations and inositol 1,3,4,5-tetrakisphosphate production.
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Increased plasma membrane permeability to Ca2+ in anti-Ig-stimulated B lymphocytes is dependent on activation of phosphoinositide hydrolysis.
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Ca2+ regulation of phosphatidylinositol turnover in the plasma membrane of tobacco suspension culture cells.
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myo-inositol metabolites as cellular signals.
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LU52396, an inhibitor of the store-dependent (capacitative) Ca2+ influx.
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Location of cAMP-dependent protein kinase type I with the TCR-CD3 complex.
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Mechanism of cAMP-induced Ca2+ influx in Dictyostelium: role of phospholipase A2.
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cAMP and inositol 1,4,5-trisphosphate increase Ca2+ in HT-29 cells by activating different Ca2+ influx pathways.
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Luminal Ca2+ increases the sensitivity of Ca2+ stores to inositol 1,4,5-trisphosphate.
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Score: 0.386 |
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[The role of inositol triphosphate and diacylglycerol as intracellular second messengers]
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Score: 0.386 |
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Involvement of phospholipase D in store-operated calcium influx in vascular smooth muscle cells.
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Score: 0.385 |
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The Ca2+-releasing messenger NAADP, a new player in the nervous system.
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Score: 0.385 |
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Ethylene glycol bis(beta-aminoethyl ether)-N,N,N',N'-tetraacetic acid (EGTA) and the tyrphostin ST271 inhibit phospholipase C in human platelets by preventing Ca2+ entry.
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Activation of Ca2+ entry into acinar cells by a non-phosphorylatable inositol trisphosphate.
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Score: 0.385 |
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The inositol 1,4,5-trisphosphate receptor is essential for T-cell receptor signaling.
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Score: 0.384 |
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CD8 expression allows T cell signaling by monomeric peptide-MHC complexes.
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Score: 0.384 |
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Composition of TCR-CD3 complex in human intestinal intraepithelial lymphocytes: lack of Fc epsilon RI gamma chain.
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Score: 0.384 |
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Score: 0.384 |
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Microfilament assembly modulates phospholipase C-mediated signal transduction by the TCR/CD3 in murine T helper lymphocytes.
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Score: 0.383 |
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Sphingosine-1-phosphate-induced intracellular Ca2+ mobilization in human endothelial cells.
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ATP stimulates inositol phosphates accumulation and calcium mobilization in a primary culture of rat aortic myocytes.
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Score: 0.383 |
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ATP, thapsigargin and cAMP increase Ca2+ in rat hepatocytes by activating three different Ca2+ influx pathways.
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Score: 0.383 |
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Different pathways for Ca2+ influx and intracellular release of Ca2+ mediated by muscarinic receptors in ileal longitudinal smooth muscle.
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Score: 0.383 |
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Capacitative Ca2+ entry in enteric glia induced by thapsigargin and extracellular ATP.
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Score: 0.383 |
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The mechanism of phospholipase C-gamma1 regulation.
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Score: 0.382 |
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7,12-Dimethylbenz[a]anthracene activates protein-tyrosine kinases Fyn and Lck in the HPB-ALL human T-cell line and increases tyrosine phosphorylation of phospholipase C-gamma 1, formation of inositol 1,4,5-trisphosphate, and mobilization of intracellular calcium.
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Score: 0.382 |
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Involvement of inositol 1,4,5-trisphosphate in Ca2+ influx in thrombin stimulated human platelets.
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Score: 0.382 |
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Micro-injection of inositol 1,3,4,5-tetrakisphosphate activates sea urchin eggs by a mechanism dependent on external Ca2+.
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Score: 0.381 |
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Change of intracellular calcium of neural cells induced by extracellular ATP.
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Score: 0.380 |
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Pituitary adenylate cyclase-activating polypeptide (PACAP) 38 and PACAP27 activate common and distinct intracellular signaling pathways to stimulate growth hormone secretion from porcine somatotropes.
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Intracellular Ca2+ activates phospholipase C.
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Score: 0.378 |
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[Mechanism of activation of receptor-operated calcium entry in non-excitable cells]
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Score: 0.378 |
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Intracellular mechanisms involved in D-glucose-mediated amplification of agonist-induced Ca2+ response and EDRF formation in vascular endothelial cells.
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Score: 0.378 |
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Inhibition by Ca2+ of inositol trisphosphate-mediated Ca2+ liberation: a possible mechanism for oscillatory release of Ca2+.
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Score: 0.378 |
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Effects of Ca2+ antagonists on NA-induced intracellular Ca2+ mobilization in rat cultured neurons.
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Facilitated calcium mobilization and inositol phosphate production in the priming effect of LH-releasing hormone in the rat.
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Score: 0.377 |
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Extracellular calcium sensing and signalling.
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Score: 0.377 |
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Calcium signalling in exocrine glands.
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Score: 0.377 |
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4-Bromophenacyl bromide induces Ca2+ influx in human gingival fibroblasts.
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Inositol trisphosphate-mediated Ca2+ influx into Xenopus oocytes triggers Ca2+ liberation from intracellular stores.
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Score: 0.376 |
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Inositol 1,4,5-trisphosphate activates two types of Ca2(+)-permeable channels in human carcinoma cells.
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Score: 0.376 |
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Histamine H1 receptor-stimulated Ca2+ signaling pathway in human periodontal ligament cells.
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Score: 0.376 |
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Inositol trisphosphate and diacylglycerol: two interacting second messengers.
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Score: 0.375 |
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Role of protein kinase C in calcium-mediated signal transduction.
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Score: 0.375 |
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Phosphoinositide metabolism and insulin secretion.
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Score: 0.375 |
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The Albert Lasker Medical Awards. Inositol trisphosphate, calcium, lithium, and cell signaling.
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Score: 0.375 |
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RACK1 binds to inositol 1,4,5-trisphosphate receptors and mediates Ca2+ release.
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Two polyphosphatidylinositide metabolites control two K+ currents in a neuronal cell.
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Score: 0.374 |
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Lead increases inositol 1,4,5-trisphosphate levels but does not interfere with calcium transients in primary rat astrocytes.
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Score: 0.374 |
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Rapid dephosphorylation of protein kinase C substrates by protein kinase A activators results from inhibition of diacylglycerol release.
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Score: 0.374 |
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Arachidonic acid plays a role in rat vomeronasal signal transduction.
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Two distinct, calcium-mediated, signal transduction pathways can trigger deflagellation in Chlamydomonas reinhardtii.
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Potentiation of depolarization-induced calcium release from skeletal muscle triads by cyclic ADP-ribose and inositol 1,4,5-trisphosphate.
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Stimulation of intracellular Ca2+ levels in human neutrophils by soluble immune complexes. Functional activation of FcgammaRIIIb during priming.
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Plasticity of cholinoreceptors of neurons of the common snail after effects on inositol-1,4,5-triphosphate- and CA(2+)-dependant mobilization of stored CA2+ and the level of phosphatidic acid.
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Ca2+ release and Ca2+ influx in Chinese hamster ovary cells expressing the cloned mouse B2 bradykinin receptor: tyrosine kinase inhibitor-sensitive and- insensitive processes.
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NPY and carbachol raise Ca2+ in SK-N-MC cells by three different mechanisms. Evidence for inositol phosphate-independent Ca2+ mobilization by NPY.
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Score: 0.373 |
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Stimulation of Ca2+ influx by endothelin-1 is subject to negative feedback by elevated intracellular Ca2+.
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Multifunctional Ca2+/calmodulin-dependent protein kinase: domain structure and regulation.
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Score: 0.372 |
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Spatiotemporal dynamics of inositol 1,4,5-trisphosphate that underlies complex Ca2+ mobilization patterns.
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The digitonin-permeabilized pancreatic islet model. Effect of myo-inositol 1,4,5-trisphosphate on Ca2+ mobilization.
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Score: 0.372 |
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Non-genomic signal transduction pathway of vitamin D in muscle.
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The roles of CD8 in cytotoxic T lymphocyte function.
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Control of Ca2+ influx in human neutrophils by inositol 1,4,5-trisphosphate (IP3) binding: differential effects of micro-injected IP3 receptor antagonists.
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Cholinergic modulation of the Ca2+ response to bradykinin in neuroblastoma cells.
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Calcium channel antagonists and renin release.
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Score: 0.371 |
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Regulation of intracellular Ca2+ and gene expression by endothelin-1.
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Mechanisms of phospholipase C-regulated calcium entry.
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Regulation of calcium influx across the plasma membrane of the human T-leukemic cell line, JURKAT: dependence on a rise in cytosolic free calcium can be dissociated from formation of inositol phosphates.
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Mobilization of intracellular calcium by glucagon and cyclic AMP analogues in isolated rat hepatocytes.
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Score: 0.370 |
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Functional properties of inositol 1,4,5-trisphosphate receptor and Ca2+ signaling.
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Release of Ca2+ from a non-mitochondrial store site in peritoneal macrophages treated with saponin by inositol 1,4,5-trisphosphate.
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Score: 0.370 |
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Inositol 1,4,5-trisphosphate is not effective in releasing calcium from skeletal sarcoplasmic reticulum microsomes.
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Score: 0.370 |
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Na+-dependent, alpha-adrenergic mobilization of intracellular (mitochondrial) Ca2+ in brown adipocytes.
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Evidence for inositol tetrakisphosphate-activated Ca2+ influx pathway refilling inositol trisphosphate-sensitive Ca2+ stores in hamster eggs.
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Inositol trisphosphate-dependent and -independent Ca2+ mobilization pathways at the vacuolar membrane of Candida albicans.
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Adenophostin A can stimulate Ca2+ influx without depleting the inositol 1,4,5-trisphosphate-sensitive Ca2+ stores in the Xenopus oocyte.
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Ca2+ and calmodulin-sensitive inositol trisphosphate kinase from bovine parathyroid.
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Hepatocyte growth factor induces calcium mobilization and inositol phosphate production in rat hepatocytes.
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Plasmalemmal dihydropyridine receptors modify the function of subplasmalemmal inositol 1,4,5-trisphosphate receptors: a hypothesis.
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Inositol 1,4,5-trisphosphate-induced Ca2+ release from permeabilized mastocytoma cells.
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Calcium transients: mobilization of intracellular Ca2+.
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Leukotriene D4 and E4 induce transmembrane signaling in human epithelial cells. Single cell analysis reveals diverse pathways at the G-protein level for the influx and the intracellular mobilization of Ca2+.
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Stimulatory effect of ursodeoxycholate on pancreatic exocrine secretion in an in vitro study.
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Ca2+/calmodulin kinase is activated by the phosphatidylinositol signaling pathway and becomes Ca2(+)-independent in PC12 cells.
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Ganglioside (GM1) distinguishes the effects of CD4 on signal transduction through the TCR/CD3 complex in human lymphocytes.
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Differential routes of Ca2+ influx in Swiss 3T3 fibroblasts in response to receptor stimulation.
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Receptor coupled events in bradykinin action: rapid production of inositol phosphates and regulation of cytosolic free Ca2+ in a neural cell line.
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[Calcium and the liver]
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Distinct roles for CD4 and CD8 as co-receptors in antigen receptor signalling.
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Inositol 1,4,5-trisphosphate and its co-players in the concert of Ca2+ signalling--new faces in the line up.
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Zymosan-induced release of inositol phosphates at resting cytosolic Ca2+ concentrations in macrophages.
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[Effects of SIN-1 on the activation of phospholipase C and calcium mobilization induced by thrombin in blood platelets]
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Apoptosis of antigen-specific T lymphocytes upon the engagement of CD8 by soluble HLA class I molecules is Fas ligand/Fas mediated: evidence for the involvement of p56lck, calcium calmodulin kinase II, and Calcium-independent protein kinase C signaling pathways and for NF-kappaB and NF-AT nuclear translocation.
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The whoosh and trickle of calcium signalling.
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Involvement of intracellular Ca2+ release mechanism in adenosine-induced cardiac Ca2+ current inhibition.
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Effects of bradykinin on Ca2+ mobilization and prostaglandin E2 release in human periodontal ligament cells.
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Inositol 1,4,5-trisphosphate releases Ca2+ from vacuolar membrane vesicles of Saccharomyces cerevisiae.
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Adrenomedullin stimulates two signal transduction pathways, cAMP accumulation and Ca2+ mobilization, in bovine aortic endothelial cells.
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Intracellular magnesium and inositol 1,4,5-trisphosphate receptor: molecular mechanisms of interaction, physiology and pharmacology.
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Intracellular Ca2+ requirements for zymosan-stimulated phosphoinositide hydrolysis in mouse peritoneal macrophages.
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Inositol phospholipids-specific phospholipase C: interaction of the gamma 1 isoform with tyrosine kinase.
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Role of the inositol phosphatase SHIP in B cell receptor-induced Ca2+ oscillatory response.
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Role of inositol (1,4,5)trisphosphate in epidermal growth factor-induced Ca2+ signaling in A431 cells.
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Co-localization of Fyn with CD3 complex, CD45 or CD28 depends on different mechanisms.
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Receptor-activated Ca2+ influx: how many mechanisms for how many channels?
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Localization and regulation of Ca2+ entry and exit pathways in exocrine gland cells.
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Testosterone induces an intracellular calcium increase by a nongenomic mechanism in cultured rat cardiac myocytes.
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Glucagon-like peptide-1 receptor expression in Xenopus oocytes stimulates inositol trisphosphate-dependent intracellular Ca2+ mobilization.
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Endothelin-3 stimulates inositol 1,4,5-trisphosphate production and Ca2+ influx to produce biphasic dopamine release from rat striatal slices.
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Activation of P2z purinoceptors diminishes the muscarinic cholinergic-induced release of inositol 1,4,5-trisphosphate and stored calcium in rat parotid acini. ATP as a co-transmitter in the stimulus-secretion coupling.
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Calmidazolium and arachidonate activate a calcium entry pathway that is distinct from store-operated calcium influx in HeLa cells.
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Hypo-osmotic shock of tobacco cells stimulates Ca2+ fluxes deriving first from external and then internal Ca2+ stores.
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Score: 0.362 |
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Ca2+ and intracellular signalling in plant cells: a role in phytochrome transduction.
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Score: 0.362 |
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Voltage-dependent Ca2+ channels in the plasma membrane and the vacuolar membrane of Arabidopsis thaliana.
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[The role of cytoskeleton structures in regulation of Ca2+ responses in macrophages]
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Score: 0.362 |
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Spontaneous calcium release from inositol trisphosphate-sensitive calcium stores.
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Score: 0.362 |
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Phosphorylation of protein kinase C by casein kinase-1.
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Score: 0.362 |
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Synergistic functions of protein phosphorylation and calcium mobilization in platelet activation.
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Score: 0.362 |
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Regulation of gene expression in hippocampal neurons by distinct calcium signaling pathways.
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Score: 0.362 |
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Modulation of Ca2+ mobilization by protein kinase C in the submandibular duct cell line A253.
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Score: 0.361 |
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Mechanisms of IL-8-induced Ca2+ signaling in human neutrophil granulocytes.
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Score: 0.361 |
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Recombinant human G protein-coupled lysophosphatidic acid receptors mediate intracellular calcium mobilization.
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Score: 0.361 |
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T cell signal transduction and the role of CD7 in costimulation.
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Score: 0.361 |
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Relations between intracellular Ca2+ stores and store-operated Ca2+ entry in primary cultured human glioblastoma cells.
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Score: 0.361 |
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Blockade of NMDA receptor-mediated mobilization of intracellular Ca2+ prevents neurotoxicity.
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Score: 0.361 |
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Interdependence of calcium signaling and protein tyrosine phosphorylation in human endothelial cells.
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Score: 0.361 |
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Luminal Ca2+ increases the affinity of inositol 1,4,5-trisphosphate for its receptor.
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Score: 0.361 |
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Studies on the enzymatic pathways of calcium ionophore-induced phospholipid degradation and arachidonic acid mobilization in peritoneal macrophages.
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Score: 0.361 |
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Activation of vanilloid receptor 1 by resiniferatoxin mobilizes calcium from inositol 1,4,5-trisphosphate-sensitive stores.
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Score: 0.361 |
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Kinin signal transduction: role of phosphoinositides and eicosanoids.
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Score: 0.361 |
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Involvement of calcium and arachidonate metabolism in acetylated-low-density-lipoprotein-stimulated tumor-necrosis-factor-alpha production by rat peritoneal macrophages.
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Score: 0.361 |
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Phospholipidic second messengers and calcium.
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Score: 0.361 |
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Reassessment of the Ca2+ sensing property of a type I metabotropic glutamate receptor by simultaneous measurement of inositol 1,4,5-trisphosphate and Ca2+ in single cells.
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Score: 0.360 |
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Inositol lipid breakdown as a step in alpha-adrenergic stimulus-response coupling.
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Score: 0.360 |
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Bradykinin-induced changes in phosphoinositides, inositol phosphate production and intracellular free calcium in cultured bovine aortic endothelial cells.
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Score: 0.360 |
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Tyrosine kinase-regulated and inositol phosphate-independent Ca2+ elevation and mobilization in T cells.
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Score: 0.359 |
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Partial T cell signaling: altered phospho-zeta and lack of zap70 recruitment in APL-induced T cell anergy.
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