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Your submitted paragraph: Proto-oncogene A term coined by M.J. Bishop in 1981, to describe the cellular homologue of a viral gene implicated in neoplastic transformation (an ONCOGENE). Proto- oncogenes serve normal cellular functions, but may contribute to neoplasia when their expression is altered by point mutation, translocation, or amplification. Examples of such genes are ras, myc and abl, prefixed with c- to distinguish them from their viral counterparts (prefixed v-).

TRITE Statistics: Extraction Method: Medical Objects Eliminated words list: MedlinePlus List Similarity Method: Keyword Count Database: Medline abstracts Publication Type: All Score Calculation Method: Cosine Similarity Method Sort by: Score Show: Top 100 hits Results computed on: 6/9/2006

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