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The control mechanism for lagging strand polymerase recycling during bacteriophage T4 DNA replication. Jingsong Yang ... Stephen J Benkovic Mol Cell 2006 Jan; 21(2)153-64. Score: 1.039 Two distinct triggers for cycling of the lagging strand polymerase at the replication fork. X Li ... K J Marians J Biol Chem 2000 Nov; 275(44)34757-65. Score: 0.974 Coordinated leading and lagging strand DNA synthesis on a minicircular template. J Lee ... C C Richardson Mol Cell 1998 Jun; 1(7)1001-10. Score: 0.924 Cytarabine-induced destabilization of a model Okazaki fragment. W H Gmeiner ... J Liu Nucleic Acids Res 1998 May; 26(10)2359-65. Score: 0.908 Eukaryotic DNA replication. Enzymes and proteins acting at the fork. P Thömmes ... U Hübscher Eur J Biochem 1990 Dec; 194(3)699-712. Score: 0.863 Lagging strand synthesis in coordinated DNA synthesis by bacteriophage t7 replication proteins. Joonsoo Lee ... Charles C Richardson J Mol Biol 2002 Feb; 316(1)19-34. Score: 0.846 Prokaryotic DNA replication mechanisms. B M Alberts Philos Trans R Soc Lond B Biol Sci 1987 Dec; 317(1187)395-420. Score: 0.841 Crystal structure of an Okazaki fragment at 2-A resolution. M Egli ... A Rich Proc Natl Acad Sci U S A 1992 Jan; 89(2)534-8. Score: 0.815 The bacteriophage T4 DNA replication fork. Only DNA helicase is required for leading strand DNA synthesis by the DNA polymerase holoenzyme. T A Cha ... B M Alberts J Biol Chem 1989 Jul; 264(21)12220-5. Score: 0.801 DNA primase acts as a molecular brake in DNA replication. Jong-Bong Lee ... Antoine M van Oijen Nature 2006 Feb; 439(7076)621-4. Score: 0.800 Okazaki fragment processing: modulation of the strand displacement activity of DNA polymerase delta by the concerted action of replication protein A, proliferating cell nuclear antigen, and flap endonuclease-1. G Maga ... U Hübscher Proc Natl Acad Sci U S A 2001 Dec; 98(25)14298-303. Score: 0.797 Replication of the lagging strand: a concert of at least 23 polypeptides. U Hübscher ... Y S Seo Mol Cells 2001 Oct; 12(2)149-57. Score: 0.792 The rapid dissociation of the T4 DNA polymerase holoenzyme when stopped by a DNA hairpin helix. A model for polymerase release following the termination of each Okazaki fragment. K J Hacker ... B M Alberts J Biol Chem 1994 Sep; 269(39)24221-8. Score: 0.791 Coordination of leading and lagging strand DNA synthesis at the replication fork of bacteriophage T7. Z Debyser ... C C Richardson Cell 1994 Apr; 77(1)157-66. Score: 0.788 Coordinated leading- and lagging-strand synthesis at the Escherichia coli DNA replication fork. I. Multiple effectors act to modulate Okazaki fragment size. C A Wu ... K J Marians J Biol Chem 1992 Feb; 267(6)4030-44. Score: 0.750 Two DNA polymerases may be required for synthesis of the lagging DNA strand of simian virus 40. T Nethanel ... G Kaufmann J Virol 1990 Dec; 64(12)5912-8. Score: 0.724 Unequal fidelity of leading strand and lagging strand DNA replication on the Escherichia coli chromosome. I J Fijalkowska ... R M Schaaper Proc Natl Acad Sci U S A 1998 Aug; 95(17)10020-5. Score: 0.724 Bacteriophage T4 RNase H removes both RNA primers and adjacent DNA from the 5' end of lagging strand fragments. M Bhagwat ... N G Nossal J Biol Chem 2001 Jul; 276(30)28516-24. Score: 0.720 PCNA acts as a stationary loading platform for transiently interacting Okazaki fragment maturation proteins. Anje Sporbert ... M Cristina Cardoso Nucleic Acids Res 2005 ; 33(11)3521-8. Score: 0.717 Protein-protein interactions at a DNA replication fork: bacteriophage T4 as a model. N G Nossal FASEB J 1992 Feb; 6(3)871-8. Score: 0.716 Discontinuous synthesis of both strands at the growing fork during polyoma DNA replication in vitro. M Närkhammar-Meuth ... G Magnusson J Virol 1981 Jul; 39(1)11-20. Score: 0.706 Cleavage of substrates with mismatched nucleotides by Flap endonuclease-1. Implications for mammalian Okazaki fragment processing. J A Rumbaugh ... R A Bambara J Biol Chem 1999 May; 274(21)14602-8. Score: 0.703 Okazaki pieces grow opposite to the replication fork direction during simian virus 40 DNA replication. G Kaufmann ... M L DePamphilis Nucleic Acids Res 1978 Jul; 5(7)2535-45. Score: 0.703 Okazaki DNA fragments contain equal amounts of lagging-strand and leading-strand sequences. T C Wang ... S H Chen Biochem Biophys Res Commun 1994 Feb; 198(3)844-9. Score: 0.693 DNA polymerases that propagate the eukaryotic DNA replication fork. Parie Garg ... Peter M J Burgers Crit Rev Biochem Mol Biol 2005 Mar-Apr; 40(2)115-28. Score: 0.688 Replication initiation point mapping. S A Gerbi ... A K Bielinsky Methods 1997 Nov; 13(3)271-80. Score: 0.683 Coordinated leading- and lagging-strand synthesis at the Escherichia coli DNA replication fork. V. Primase action regulates the cycle of Okazaki fragment synthesis. C A Wu ... K J Marians J Biol Chem 1992 Feb; 267(6)4074-83. Score: 0.683 Evidence for preferential mismatch repair of lagging strand DNA replication errors in yeast. Youri I Pavlov ... Thomas A Kunkel Curr Biol 2003 Apr; 13(9)744-8. Score: 0.678 Replisome assembly reveals the basis for asymmetric function in leading and lagging strand replication. A Yuzhakov ... M O'Donnell Cell 1996 Sep; 86(6)877-86. Score: 0.674 Discontinuous DNA replication in mouse P-815 cells. J R Gautschi ... J M Clarkson Eur J Biochem 1975 Jan; 50(2)403-12. Score: 0.674 Sequential initiation of lagging and leading strand synthesis by two different polymerase complexes at the SV40 DNA replication origin. T Tsurimoto ... B Stillman Nature 1990 Aug; 346(6284)534-9. Score: 0.672 Effect of cytarabine on the NMR structure of a model okazaki fragment from the SV40 genome. W H Gmeiner ... T L James Biochemistry 1999 Jan; 38(4)1166-75. Score: 0.665 In vitro repair of radiation-induced strand breaks in DNA. L Mitzel-Landbeck ... U Hagen Biochim Biophys Acta 1976 May; 432(2)145-53. Score: 0.662 The application of a minicircle substrate in the study of the coordinated T4 DNA replication. Jingsong Yang ... Stephen J Benkovic J Biol Chem 2003 Dec; 278(50)49828-38. Score: 0.660 Formation of a DNA loop at the replication fork generated by bacteriophage T7 replication proteins. K Park ... J D Griffith J Biol Chem 1998 Feb; 273(9)5260-70. Score: 0.659 An explanation for lagging strand replication: polymerase hopping among DNA sliding clamps. P T Stukenberg ... M O'Donnell Cell 1994 Sep; 78(5)877-87. Score: 0.657 Completion of mammalian lagging strand DNA replication using purified proteins. J J Turchi ... R A Bambara J Biol Chem 1993 Jul; 268(20)15136-41. Score: 0.657 Preferential DNA secondary structure mutagenesis in the lagging strand of replication in E. coli. T Q Trinh ... R R Sinden Nature 1991 Aug; 352(6335)544-7. Score: 0.655 Greater susceptibility to mutations in lagging strand of DNA replication in Escherichia coli than in leading strand. X Veaute ... R P Fuchs Science 1993 Jul; 261(5121)598-600. Score: 0.653 Site-specific initiation of a DNA fragment. D Hourcade ... D Dressler Proc Natl Acad Sci U S A 1978 Apr; 75(4)1652-6. Score: 0.652 Coordinated leading- and lagging-strand synthesis at the Escherichia coli DNA replication fork. II. Frequency of primer synthesis and efficiency of primer utilization control Okazaki fragment size. E L Zechner ... K J Marians J Biol Chem 1992 Feb; 267(6)4045-53. Score: 0.651 Eukaryotic DNA polymerases in DNA replication and DNA repair. P M Burgers Chromosoma 1998 Sep; 107(4)218-27. Score: 0.650 The DNA polymerase alpha-primase complex couples DNA replication, cell-cycle progression and DNA-damage response. M Foiani ... P Plevani Trends Biochem Sci 1997 Nov; 22(11)424-7. Score: 0.648 Replication of kinetoplast DNA in Trypanosoma equiperdum. Minicircle H strand fragments which map at specific locations. K A Ryan ... P T Englund J Biol Chem 1989 Jan; 264(2)823-30. Score: 0.645 Architecture of the replication complex and DNA loops at the fork generated by the bacteriophage t4 proteins. Paul D Chastain ... Jack Griffith J Biol Chem 2003 Jun; 278(23)21276-85. Score: 0.643 Simultaneous formation of functional leading and lagging strand holoenzyme complexes on a small, defined DNA substrate. A J Berdis ... S J Benkovic Proc Natl Acad Sci U S A 1998 Sep; 95(19)11128-33. Score: 0.640 Fate of DNA replication fork encountering a single DNA lesion during oriC plasmid DNA replication in vitro. Kumiko Higuchi ... Hisaji Maki Genes Cells 2003 May; 8(5)437-49. Score: 0.640 Mechanism of DNA replication possible discontinuity of DNA chain growth. R Okazaki ... K Sugimoto Jpn J Med Sci Biol 1967 Jun; 20(3)255-60. Score: 0.637 How the cell deals with DNA nicks. Parie Garg ... Peter M J Burgers Cell Cycle 2005 Feb; 4(2)221-4. Score: 0.630 DNA replication: partners in the Okazaki two-step. S A MacNeill Curr Biol 2001 Oct; 11(20)R842-4. Score: 0.629 Dissociation of bacteriophage T4 DNA polymerase and its processivity clamp after completion of Okazaki fragment synthesis. T E Carver ... S J Benkovic Biochemistry 1997 Nov; 36(47)14409-17. Score: 0.629 Characterization of the enzymatic properties of the yeast dna2 Helicase/endonuclease suggests a new model for Okazaki fragment processing. S H Bae ... Y S Seo J Biol Chem 2000 Dec; 275(48)38022-31. Score: 0.628 The interaction between helicase and primase sets the replication fork clock. K Tougu ... K J Marians J Biol Chem 1996 Aug; 271(35)21398-405. Score: 0.627 tau couples the leading- and lagging-strand polymerases at the Escherichia coli DNA replication fork. S Kim ... K J Marians J Biol Chem 1996 Aug; 271(35)21406-12. Score: 0.627 An Okazaki piece of simian virus 40 may be synthesized by ligation of shorter precursor chains. T Nethanel ... G Kaufmann J Virol 1988 Aug; 62(8)2867-73. Score: 0.626 The F plasmid may cosegregrate with either DNA strand of the Escherichia coli chromosome. P J Leibowitz ... M S Fox J Bacteriol 1978 Oct; 136(1)455-9. Score: 0.623 A preformed, topologically stable replication fork. Characterization of leading strand DNA synthesis catalyzed by T7 DNA polymerase and T7 gene 4 protein. R L Lechner ... C C Richardson J Biol Chem 1983 Sep; 258(18)11185-96. Score: 0.619 Expression of a DNA strand initiation sequence of ColE1 plasmid in a single-stranded DNA phage. N Nomura ... D S Ray Proc Natl Acad Sci U S A 1980 Nov; 77(11)6566-70. Score: 0.616 Coordinated leading and lagging strand synthesis during SV40 DNA replication in vitro requires PCNA. G Prelich ... B Stillman Cell 1988 Apr; 53(1)117-26. Score: 0.616 Assay of RNA-linked nascent DNA pieces with polynucleotide kinase. R Okazaki ... Y Kurosawa Biochem Biophys Res Commun 1975 Feb; 62(4)1018-24. Score: 0.609 Architecture of the replication fork stalled at the 3' end of yeast ribosomal genes. M Gruber ... J M Sogo Mol Cell Biol 2000 Aug; 20(15)5777-87. Score: 0.608 Mechanism of DNA chain growth XVI. Analyses of RNA-linked DNA pieces in Escherichia coli with polynucleotide kinase. T Ogawa ... R Okazaki J Mol Biol 1977 May; 112(1)121-40. Score: 0.602 DNA substrate structural requirements for the exonuclease and polymerase activities of procaryotic and phage DNA polymerases. M Cowart ... S J Benkovic Biochemistry 1989 Mar; 28(5)1975-83. Score: 0.602 The molecular structure of Okazaki fragment r(CGCA)d(AAAAAGCG):d(CGCTTTTTTGCG) in solution. S Fujii ... S Uesugi Nucleic Acids Symp Ser 1989 ; (21)67-8. Score: 0.599 The DNA polymerase III holoenzyme: an asymmetric dimeric replicative complex with leading and lagging strand polymerases. B P Glover ... C S McHenry Cell 2001 Jun; 105(7)925-34. Score: 0.598 Strand asymmetry in human mitochondrial DNA mutations. M Tanaka ... T Ozawa Genomics 1994 Jul; 22(2)327-35. Score: 0.596 Bacteriophage T7 DNA replication. Synthesis of lagging strands in a reconstituted system using purified proteins. M J Engler ... C C Richardson J Biol Chem 1983 Sep; 258(18)11197-205. Score: 0.595 Mapping replication fork direction by leading strand analysis. M I Aladjem ... G M Wahl Methods 1997 Nov; 13(3)281-92. Score: 0.594 Strand asymmetries in DNA evolution. M P Francino ... H Ochman Trends Genet 1997 Jun; 13(6)240-5. Score: 0.594 Multiple mechanisms for initiation of ColE1 DNA replication: DNA synthesis in the presence and absence of ribonuclease H. S Dasgupta ... J Tomizawa Cell 1987 Dec; 51(6)1113-22. Score: 0.594 Replication strand preference for deletions associated with DNA palindromes. D J Pinder ... D R Leach Mol Microbiol 1998 May; 28(4)719-27. Score: 0.593 Rescue of stalled replication forks by RecG: simultaneous translocation on the leading and lagging strand templates supports an active DNA unwinding model of fork reversal and Holliday junction formation. P McGlynn ... R G Lloyd Proc Natl Acad Sci U S A 2001 Jul; 98(15)8227-34. Score: 0.593 Characterization of the bacteriophage T4 gene 41 DNA helicase. R W Richardson ... N G Nossal J Biol Chem 1989 Mar; 264(8)4725-31. Score: 0.593 Biochemical characterization of the DNA substrate specificity of Werner syndrome helicase. Robert M Brosh ... Joshua A Sommers J Biol Chem 2002 Jun; 277(26)23236-45. Score: 0.591 Coordinated leading- and lagging-strand synthesis at the Escherichia coli DNA replication fork. IV. Reconstitution of an asymmetric, dimeric DNA polymerase III holoenzyme. C A Wu ... K J Marians J Biol Chem 1992 Feb; 267(6)4064-73. Score: 0.590 Metabolism of Okazaki fragments during simian virus 40 DNA replication. S Anderson ... M L DePamphilis J Biol Chem 1979 Nov; 254(22)11495-504. Score: 0.589 Characterization of DNA polymerase induced by bacteriophage T5 with DNA containing single strand breaks. R K Fujimura ... B C Roop J Biol Chem 1976 Apr; 251(7)2168-74. Score: 0.588 Bacteriophage P2 DNA replication. Characterization of the requirement of the gene B protein in vivo. B E Funnell ... R B Inman J Mol Biol 1983 Jun; 167(2)311-34. Score: 0.588 Discontinuous DNA replication. T Ogawa ... T Okazaki Annu Rev Biochem 1980 ; 49()421-57. Score: 0.586 A peptide switch regulates DNA polymerase processivity. Francisco J López de Saro ... Mike O'Donnell Proc Natl Acad Sci U S A 2003 Dec; 100(25)14689-94. Score: 0.586 Both strands of polyoma DNA are replicated discontinuously with ribonucleotide primers in vivo. M Närkhammar-Meuth ... D T Denhardt J Virol 1981 Jul; 39(1)21-30. Score: 0.584 Specific function of DNA ligase I in simian virus 40 DNA replication by human cell-free extracts is mediated by the amino-terminal non-catalytic domain. V J Mackenney ... T Lindahl J Biol Chem 1997 Apr; 272(17)11550-6. Score: 0.582 Twin DNA pumps of a hexameric helicase provide power to simultaneously melt two duplexes. Daniel L Kaplan ... Mike O'Donnell Mol Cell 2004 Aug; 15(3)453-65. Score: 0.581 Primer terminus recognition and highly processive replication by Epstein-Barr virus DNA polymerase. T Tsurumi Biochem J 1991 Dec; 280 ( Pt 3)()703-8. Score: 0.581 Double-strand break repair in yeast requires both leading and lagging strand DNA polymerases. A M Holmes ... J E Haber Cell 1999 Feb; 96(3)415-24. Score: 0.580 Heteroduplex formation by recA protein: polarity of strand exchanges. S C West ... P Howard-Flanders Proc Natl Acad Sci U S A 1981 Oct; 78(10)6149-53. Score: 0.579 Mechanism of DNA chain growth. 3. Equal annealing of T4 nascent short DNA chains with the separated complementary strands of the phage DNA. K Sugimoto ... R Okazaki Proc Natl Acad Sci U S A 1969 Aug; 63(4)1343-50. Score: 0.579 Role of polynucleotide ligase and DNA polymerase in the repair of DNA damage. K Ebisuzaki J Mol Biol 1969 Jun; 42(2)375-8. Score: 0.579 Helix-destabilizing properties of the adenovirus DNA-binding protein. D C Zijderveld ... P C van der Vliet J Virol 1994 Feb; 68(2)1158-64. Score: 0.578 Persistence of RNA attached to nascent short DNA pieces in Bacillus subtilis cells defective in DNA polymerase I. F Tamanoi ... R Okazaki Biochem Biophys Res Commun 1977 Jul; 77(1)290-7. Score: 0.577 T7 RNA polymerase bypass of large gaps on the template strand reveals a critical role of the nontemplate strand in elongation. W Zhou ... P W Doetsch Cell 1995 Aug; 82(4)577-85. Score: 0.574 Complete enzymatic synthesis of DNA containing the SV40 origin of replication. Y Ishimi ... J Hurwitz J Biol Chem 1988 Dec; 263(36)19723-33. Score: 0.574 Structure of DNA polymerase I Klenow fragment bound to duplex DNA. L S Beese ... T A Steitz Science 1993 Apr; 260(5106)352-5. Score: 0.574 The DNA replication fork in eukaryotic cells. S Waga ... B Stillman Annu Rev Biochem 1998 ; 67()721-51. Score: 0.573 Repair of single strand breaks in transforming DNA by polynucleotide ligase. J Takagi ... Y Ikeda Biochem Biophys Res Commun 1968 May; 31(4)540-4. Score: 0.572 Imbalanced DNA synthesis induced by cytosine arabinoside and fludarabine in human leukemia cells. G M Carbone ... D J Fernandes Biochem Pharmacol 2001 Jul; 62(1)101-10. Score: 0.572 Uncoupling of leading- and lagging-strand DNA replication during lesion bypass in vivo. Vincent Pagès ... Robert P Fuchs Science 2003 May; 300(5623)1300-3. Score: 0.571 Physical map and strand polarity of specific fragments of adenovirus-associated virus DNA produced by endonuclease R-EcoRI. B J Carter ... D T Denhardt J Virol 1975 Sep; 16(3)559-68. Score: 0.571 Cleavage of model replication forks by fission yeast Mus81-Eme1 and budding yeast Mus81-Mms4. Matthew C Whitby ... Julie Dixon J Biol Chem 2003 Feb; 278(9)6928-35. Score: 0.571 Requirements for synthesis of ribonucleic acid primers during lagging strand synthesis by the DNA polymerase and gene 4 protein of bacteriophage T7. L J Romano ... C C Richardson J Biol Chem 1979 Oct; 254(20)10476-82. Score: 0.570 Anatomy of a DNA replication fork revealed by reconstitution of SV40 DNA replication in vitro. S Waga ... B Stillman Nature 1994 May; 369(6477)207-12. Score: 0.570 DNA polymerase delta: a second eukaryotic DNA replicase. K M Downey ... A G So Bioessays 1990 May; 12(5)231-6. Score: 0.570 Arrangement of the single-stranded fragments in E. coli bacteriophage BF23 DNA. K Okada ... Y Shimura Gene 1980 Mar; 8(4)345-68. Score: 0.570 On RecA protein-mediated homologous alignment of two DNA molecules. Three strands versus four strands. J E Lindsley ... M M Cox J Biol Chem 1990 Jun; 265(17)10164-71. Score: 0.569 Structure of the replication fork in ultraviolet light-irradiated human cells. M Cordeiro-Stone ... R Meneghini Biophys J 1979 Aug; 27(2)287-300. Score: 0.568 Role of the Escherichia coli RecQ DNA helicase in SOS signaling and genome stabilization at stalled replication forks. Takashi Hishida ... Hideo Shinagawa Genes Dev 2004 Aug; 18(15)1886-97. Score: 0.566 Rifampicin-resistant initiation of DNA synthesis on the isolated strands of ColE plasmid DNA. T W Böldicke ... W L Staudenbauer Nucleic Acids Res 1981 Oct; 9(20)5215-31. Score: 0.566 Reconstitution of complete SV40 DNA replication with purified replication factors. S Waga ... B Stillman J Biol Chem 1994 Apr; 269(14)10923-34. Score: 0.565 Replisome-mediated DNA replication. S J Benkovic ... F Salinas Annu Rev Biochem 2001 ; 70()181-208. Score: 0.565 Replication of the colicin E1 plasmid in extracts of Escherichia coli: uncoupling of leading strand from lagging strand synthesis. W L Staudenbauer ... E Lanka Mol Gen Genet 1979 ; 177(1)113-20. Score: 0.564 Functional analysis of the dna (Ts) mutants of Bacillus subtilis: plasmid pUB110 replication as a model system. J C Alonso ... J F Viret Mol Gen Genet 1988 Nov; 214(3)482-9. Score: 0.564 Consequences of 6-thioguanine incorporation into DNA on polymerase, ligase, and endonuclease reactions. Y H Ling ... J A Nelson Mol Pharmacol 1992 Nov; 42(5)802-7. Score: 0.564 Lagging strand DNA synthesis at the eukaryotic replication fork involves binding and stimulation of FEN-1 by proliferating cell nuclear antigen. X Li ... P M Burgers J Biol Chem 1995 Sep; 270(38)22109-12. Score: 0.564 2-Chloro-2'-deoxyadenosine monophosphate residues in DNA enhance susceptibility to 3'-->5' exonucleases. P Hentosh ... P Grippo Biochem J 1994 Sep; 302 ( Pt 2)()567-71. Score: 0.564 Replication protein A as a "fidelity clamp" for DNA polymerase alpha. G Maga ... U Hubscher J Biol Chem 2001 May; 276(21)18235-42. Score: 0.564 Assembly of simian virus 40 Okazaki pieces from DNA primers is reversibly arrested by ATP depletion. T Nethanel ... G Kaufmann J Virol 1992 Nov; 66(11)6634-40. Score: 0.563 A conserved interaction between the replicative clamp loader and DNA ligase in eukaryotes: implications for Okazaki fragment joining. David S Levin ... Alan E Tomkinson J Biol Chem 2004 Dec; 279(53)55196-201. Score: 0.563 Similar-sized daughter-strand gaps are produced in the leading and lagging strands of DNA in UV-irradiated E. coli uvrA cells. T C Wang ... S H Chen Biochem Biophys Res Commun 1992 May; 184(3)1496-503. Score: 0.563 DNA replication: one strand may be more equal. M Radman Proc Natl Acad Sci U S A 1998 Aug; 95(17)9718-9. Score: 0.562 Bacteriophage Mu DNA replication in vitro. N P Higgins ... B M Olivera J Biol Chem 1983 Apr; 258(7)4293-7. Score: 0.561 Analysis of the Okazaki fragment distributions along single long DNAs replicated by the bacteriophage T4 proteins. P D Chastain ... J D Griffith Mol Cell 2000 Oct; 6(4)803-14. Score: 0.561 The solution structure of the r(gcg)d(TATACCC):d(GGGTATACGC) Okazaki fragment contains two distinct duplex morphologies connected by a junction. M Salazar ... B R Reid J Mol Biol 1994 Aug; 241(3)440-55. Score: 0.561 The large fragment of Escherichia coli DNA polymerase I can synthesize DNA exclusively from fluorescently labeled nucleotides. S Brakmann ... P Nieckchen Chembiochem 2001 Oct; 2(10)773-7. Score: 0.559 [Coordination of leading and lagging DNA in strand replication] I J Fijałkowska ... P Jonczyk Postepy Biochem 1997 ; 43(2)98-104. Score: 0.558 Enzymatic repair of UV-irradiated DNA in vitro. L D Hamilton ... L Grossman Basic Life Sci 1975 ; 5A()235-43. Score: 0.558 Mechanism of DNA chain growth. XIII. Evidence for discontinuous replication of both strands of P2 phage DNA. Y Kurosawa ... R Okazaki J Mol Biol 1975 May; 94(2)229-41. Score: 0.558 Identification of the heavy strand of rat-liver mitochondrial DNA as the messenger strand. P Borst ... C Aaij Biochem Biophys Res Commun 1969 Feb; 34(3)358-64. Score: 0.558 Mechanism of DNA A protein-dependent pBR322 DNA replication. DNA A protein-mediated trans-strand loading of the DNA B protein at the origin of pBR322 DNA. C A Parada ... K J Marians J Biol Chem 1991 Oct; 266(28)18895-906. Score: 0.558 Minimal DNA duplex requirements for topoisomerase I-mediated cleavage in vitro. J Q Svejstrup ... O Westergaard J Biol Chem 1990 Jul; 265(21)12529-35. Score: 0.558 Efficient in vitro replication of double-stranded DNA templates by a purified T4 bacteriophage replication system. N K Sinha ... B M Alberts J Biol Chem 1980 May; 255(9)4290-3. Score: 0.558 Dissociative properties of the proteins within the bacteriophage T4 replisome. Michael A Trakselis ... Stephen J Benkovic J Biol Chem 2003 Dec; 278(50)49839-49. Score: 0.558 The gene 4 protein of bacteriophage T7. Characterization of helicase activity. S W Matson ... C C Richardson J Biol Chem 1983 Nov; 258(22)14017-24. Score: 0.556 Replication slippage involves DNA polymerase pausing and dissociation. E Viguera ... S D Ehrlich EMBO J 2001 May; 20(10)2587-95. Score: 0.556 Aphidicolin inhibits the synthesis and joining of short DNA fragments but not the union of 10-kilobase DNA replication intermediates. U Lönn ... S Lönn Proc Natl Acad Sci U S A 1983 Jul; 80(13)3996-9. Score: 0.556 RNA primer removal and gap filling on a model minicircle replication intermediate. J C Hines ... D S Ray Mol Biochem Parasitol 2001 Jun; 115(1)63-7. Score: 0.553 Studies on the transcription complex of Escherichia coli RNA polymerase. H Rohrer ... W Zillig Eur J Biochem 1977 Oct; 79(2)401-9. Score: 0.553 The crystal structure of the bifunctional primase-helicase of bacteriophage T7. Eric A Toth ... Tom Ellenberger Mol Cell 2003 Nov; 12(5)1113-23. Score: 0.552 Initiation site of deoxyribonucleotide polymerization at the replication origin of the Escherichia coli chromosome. S Hirose ... T Okazaki Mol Gen Genet 1983 ; 189(3)422-31. Score: 0.552 Replication of single-stranded plasmid pT181 DNA in vitro. P Birch ... S A Khan Proc Natl Acad Sci U S A 1992 Jan; 89(1)290-4. Score: 0.552 Leading and lagging strand DNA synthesis in vitro by a reconstituted herpes simplex virus type 1 replisome. M Falkenberg ... P Elias Proc Natl Acad Sci U S A 2000 Apr; 97(8)3896-900. Score: 0.552 The DNA polymerase alpha-primase complex: multiple functions and interactions. Marco Muzi-Falconi ... Paolo Plevani ScientificWorldJournal 2003 Mar; 3()21-33. Score: 0.550 A heterotrimeric PCNA in the hyperthermophilic archaeon Sulfolobus solfataricus. Isabelle Dionne ... Stephen D Bell Mol Cell 2003 Jan; 11(1)275-82. Score: 0.549 DNA strand asymmetry. C I Wu Nature 1991 Jul; 352(6331)114. Score: 0.549 Initiation sites for discontinuous DNA synthesis of bacteriophage T7. A Fujiyama ... T Okazaki Proc Natl Acad Sci U S A 1981 Feb; 78(2)903-7. Score: 0.548 Fidelity of replication of the leading and the lagging DNA strands opposite N-methyl-N-nitrosourea-induced DNA damage in human cells. T Basic-Zaninovic ... E Dogliotti Nucleic Acids Res 1992 Dec; 20(24)6543-8. Score: 0.546 The replication of DNA II. The number of polynucleotide strands in the conserved unit of DNA. L F CAVALIERI ... B H ROSENBERG Biophys J 1961 Mar; 1()323-36. Score: 0.546 Discontinuous DNA synthesis by purified mammalian proteins. M Goulian ... B M Bigsby J Biol Chem 1990 Oct; 265(30)18461-71. Score: 0.545 The Escherichia coli dnaB replication protein is a DNA helicase. J H LeBowitz ... R McMacken J Biol Chem 1986 Apr; 261(10)4738-48. Score: 0.545 Evidence that both growing DNA chains at a replication fork are synthesized discontinuously. R Sternglanz ... J J Donegan Biochemistry 1976 May; 15(9)1838-43. Score: 0.542 E. coli recA protein possesses a strand separating activity on short duplex DNAs. M Bianchi ... G Magni EMBO J 1985 Nov; 4(11)3025-30. Score: 0.542 Differential replication of a single, UV-induced lesion in the leading or lagging strand by a human cell extract: fork uncoupling or gap formation. D L Svoboda ... J M Vos Proc Natl Acad Sci U S A 1995 Dec; 92(26)11975-9. Score: 0.542 Molecular biology of carcinogenesis. 3. Relations between the two strands of DNA, the normal cell mRNA and the mRNA from virus-transformed cells, proving the existence of a genetic strand (gDNA) and an informational strand (iDNA) in duplex DNA. Y Valladares ... T Pintado Med Exp Int J Exp Med 1968 ; 18(4)283-98. Score: 0.542 Enzyme action at 3' termini of ionizing radiation-induced DNA strand breaks. W D Henner ... W A Haseltine J Biol Chem 1983 Dec; 258(24)15198-205. Score: 0.542 DNA synthesis in a mitochondrial lysate of Xenopus laevis oocytes. H strand replication in vitro. D Dunon-Bluteau ... G Brun J Mol Biol 1987 Sep; 197(2)175-85. Score: 0.541 In vitro expansion of GGC:GCC repeats: identification of the preferred strand of expansion. J Ji ... L A Loeb Nucleic Acids Res 1996 Jul; 24(14)2835-40. Score: 0.540 Influence of poly(ADP-ribose) polymerase on the enzymatic synthesis of SV40 DNA. T Eki ... J Hurwitz J Biol Chem 1991 Feb; 266(5)3087-100. Score: 0.540 Enzymatic multiplication of a chemically synthesized DNA fragment. K Olson ... C Harvey Nucleic Acids Res 1975 Jan; 2(1)43-60. Score: 0.540 Synthesis of the mammalian telomere lagging strand in vitro. P M Reveal ... J J Turchi J Biol Chem 1997 May; 272(18)11678-81. Score: 0.539 A DNA fragment from the origin of single-strand to double-strand DNA replication of bacteriophage fd. H Schaller ... K Geider Proc Natl Acad Sci U S A 1976 Jan; 73(1)49-53. Score: 0.537 Cycling of Escherichia coli DNA polymerase III from one sliding clamp to another: model for lagging strand. J Turner ... M O'Donnell Methods Enzymol 1995 ; 262()442-9. Score: 0.537 Maximal limits of the Escherichia coli replication factor Y effector site sequences in pBR322 DNA. K J Marians ... S L Zipursky J Biol Chem 1982 May; 257(10)5656-62. Score: 0.537 Accurate in vitro translesion synthesis by Escherichia coli DNA polymerase I (large fragment) on a site-specific, aminofluorene-modified oligonucleotide. M L Michaels ... L J Romano Carcinogenesis 1991 Sep; 12(9)1641-6. Score: 0.537 Telomerase and DNA end replication: no longer a lagging strand problem? J Lingner ... T R Cech Science 1995 Sep; 269(5230)1533-4. Score: 0.536 Lagging strand replication proteins in genome stability and DNA repair. Marie L Rossi ... Robert A Bambara Chem Rev 2006 Feb; 106(2)453-73. Score: 0.536 Characterization of strand displacement synthesis catalyzed by bacteriophage T7 DNA polymerase. R L Lechner ... C C Richardson J Biol Chem 1983 Sep; 258(18)11174-84. 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Score: 0.533 [RNA fragments rich in G and A nucleotides obligatory for in vitro DNA replication of phages phi-X 174 and lambda] M M Beljanski C R Acad Sci Hebd Seances Acad Sci D 1975 Mar; 280(9)1189-92. Score: 0.533 Discontinuous replication of replicative form DNA from bacteriophage phiX174. Y Machida ... R Okazaki Proc Natl Acad Sci U S A 1977 Jul; 74(7)2776-9. Score: 0.533 Differential DNA secondary structure-mediated deletion mutation in the leading and lagging strands. W A Rosche ... R R Sinden J Bacteriol 1995 Aug; 177(15)4385-91. Score: 0.532 Structure of chimeric duplex junctions: solution conformation of the retroviral Okazaki-like fragment r(ccca)d(AATGA).d(TCATTTGGG) from Moloney murine leukemia virus. M Salazar ... B R Reid Biochemistry 1996 Jun; 35(25)8126-35. Score: 0.532 Rearrangements between differently replicating DNA strands in asymmetric bacterial genomes. Dorota Mackiewicz ... Stanisław Cebrat Acta Microbiol Pol 2003 ; 52(3)245-60. 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Kenneth J Marians J Biol Chem 2002 Apr; 277(16)14321-8. Score: 0.520 Initiation mechanisms in replication of filamentous phage DNA. K Horiuchi Genes Cells 1997 Jul; 2(7)425-32. Score: 0.519 Differential replication of a single N-2-acetylaminofluorene lesion in the leading or lagging strand DNA in a human cell extract. X Veaute ... A Sarasin J Biol Chem 1997 Jun; 272(24)15351-7. Score: 0.519 The mechanism of action of an accessory protein for DNA polymerase alpha/primase. M Goulian ... C J Heard J Biol Chem 1990 Aug; 265(22)13231-9. Score: 0.519 Properties of a DNA ligase mutant of Escherichia coli: introduction of strand breaks in DNA. C Pauling ... S P Wilczynski J Gen Microbiol 1976 Jun; 94(2)297-304. Score: 0.519 UV lesions located on the leading strand inhibit DNA replication but do not inhibit SV40 T-antigen helicase activity. X Veaute ... A Sarasin Mutat Res 2000 Feb; 459(1)19-28. Score: 0.519 Isolation of circular viral and complementary strand DNA from bacteriophage f1 duplex replicative-form DNA. M L Bayne ... L B Dumas Anal Biochem 1978 Dec; 91(2)432-40. Score: 0.518 Mechanism of DNA chain growth. IV. Direction of synthesis of T4 short DNA chains as revealed by exonucleolytic degradation. T Okazaki ... R Okazaki Proc Natl Acad Sci U S A 1969 Dec; 64(4)1242-8. Score: 0.518 Recombination by strand assimilation and strand crossover. M Chipchase J Theor Biol 1976 Apr; 57(2)249-79. Score: 0.518 Stoichiometry and DNA unwinding by the bacteriophage T4 41:59 helicase. K D Raney ... S J Benkovic J Biol Chem 1996 Jun; 271(24)14074-81. Score: 0.516 Mammalian DNA helicase. U Hübscher ... H P Stalder Nucleic Acids Res 1985 Aug; 13(15)5471-83. Score: 0.515 The acidic carboxyl terminus of the bacteriophage T7 gene 4 helicase/primase interacts with T7 DNA polymerase. S M Notarnicola ... C C Richardson J Biol Chem 1997 Jul; 272(29)18425-33. Score: 0.514 Unwinding of the nascent lagging strand by Rep and PriA enables the direct restart of stalled replication forks. Ryan C Heller ... Kenneth J Marians J Biol Chem 2005 Oct; 280(40)34143-51. Score: 0.514 Determination of the 3' terminal nucleotide of DNA fragments. K Olson ... C Harvey Nucleic Acids Res 1975 Mar; 2(3)319-25. Score: 0.512 Strand specificity of DNA unwinding by RecBCD enzyme. G Braedt ... G R Smith Proc Natl Acad Sci U S A 1989 Feb; 86(3)871-5. Score: 0.511 Formation of nascent heteroduplex structures by RecA protein and DNA. A M Wu ... C M Radding Cell 1982 Aug; 30(1)37-44. Score: 0.511 Simian virus 40 DNA replication: characterization of gaps in the termination region. M C Chen ... N P Salzman J Virol 1976 Feb; 17(2)614-21. Score: 0.510 Structure of a replication intermediate in the synthesis of Rous sarcoma virus DNA in vivo. R Swanstrom ... H E Varmus J Virol 1982 Apr; 42(1)337-41. Score: 0.510 Change in priming sites for discontinuous DNA synthesis between the monomeric and concatemeric stages of phage T7 replication. K Sugimoto ... T Okazaki Mol Gen Genet 1988 Mar; 211(3)400-6. Score: 0.510 Synthesis of non-natural DNA using DNA polymerase. Y Ebara ... S Ueji Nucleic Acids Symp Ser 2000 ; (44)143-4. Score: 0.510 An extracellular nuclease of Bacillus subtilis: some novel properties as a DNA exonuclease. R Okazaki ... K Sakabe Biochem Biophys Res Commun 1966 Mar; 22(6)611-9. Score: 0.510 One left-handed strand in DNA-oligonucleotide complexes? F Gago ... W G Richards FEBS Lett 1989 Jan; 242(2)270-4. Score: 0.509 Polynucleotide ligase and phiX174 single strand synthesis. R W Schekman ... D S Ray Nat New Biol 1971 Jun; 231(23)170-3. Score: 0.509 An RNA transcribed from DNA at the origin of phage fd single strand to replicative form conversion. K Geider ... H Schaller Proc Natl Acad Sci U S A 1978 Feb; 75(2)645-9. 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T S Hsieh J Biol Chem 1989 Aug; 264(23)13510-8. Score: 0.503 Mammalian DNA polymerase alpha holoenzymes with possible functions at the leading and lagging strand of the replication fork. H P Ottiger ... U Hübscher Proc Natl Acad Sci U S A 1984 Jul; 81(13)3993-7. Score: 0.503 DNA strand transfer catalyzed by the 5'-3' exonuclease domain of Escherichia coli DNA polymerase I. W Zhang ... D H Evans Nucleic Acids Res 1995 Nov; 23(22)4620-7. Score: 0.502 Replication fork reactivation downstream of a blocked nascent leading strand. Ryan C Heller ... Kenneth J Marians Nature 2006 Feb; 439(7076)557-62. Score: 0.502 A complex of the bacteriophage T7 primase-helicase and DNA polymerase directs primer utilization. M Kato ... T Ellenberger J Biol Chem 2001 Jun; 276(24)21809-20. Score: 0.501 Do DNA polymerases delta and alpha act coordinately as leading and lagging strand replicases? F Focher ... U Hübscher FEBS Lett 1988 Feb; 229(1)6-10. 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Score: 0.499 Inequality in mutation rates of the two strands of DNA. C I Wu ... N Maeda Nature 1987 May 14-20; 327(6118)169-70. Score: 0.499 Replication factors required for SV40 DNA replication in vitro. II. Switching of DNA polymerase alpha and delta during initiation of leading and lagging strand synthesis. T Tsurimoto ... B Stillman J Biol Chem 1991 Jan; 266(3)1961-8. Score: 0.498 An analysis of DNA replication in synchronized CHO cells treated with benzo[a]pyrene diol epoxide. D T Yamanishi ... A E Cress Biochim Biophys Acta 1987 Oct; 910(1)34-42. Score: 0.498 The fidelity of the human leading and lagging strand DNA replication apparatus with 8-oxodeoxyguanosine triphosphate. D T Minnick ... T A Kunkel Nucleic Acids Res 1994 Dec; 22(25)5658-64. Score: 0.498 DNA replication and transcription direct a DNA strand bias in the process of targeted gene repair in mammalian cells. Erin E Brachman ... Eric B Kmiec J Cell Sci 2004 Aug; 117(Pt 17)3867-74. Score: 0.498